Gene Information

Name : glnA (YPO0024)
Accession : YP_002345120.1
Strain : Yersinia pestis CO92
Genome accession: NC_003143
Putative virulence/resistance : Virulence
Product : glutamine synthetase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0174
EC number : 6.3.1.2
Position : 33131 - 34540 bp
Length : 1410 bp
Strand : -
Note : forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltra

DNA sequence :
ATGTCCGCTGAACATGTTTTGACGATGCTGAATGAGCACGAAGTGAAATTTGTTGATTTACGTTTCACTGATACCAAAGG
GAAAGAGCAGCACATCACGATCCCTGCTCATCAAGTCAACGCTGACTTCTTCGAAGAAGGCAAAATGTTTGATGGCTCCT
CGATTGGTGGCTGGAAAGGCATTAACGAATCCGACATGGTACTGATGCCAGACGCCAGCACTGCCGTTATGGACCCGTTC
TTCGCAGATTCAACACTGATTATCCGTTGTGACATTCTTGAGCCAGGCACCATGCAGGGCTATGACCGCGATCCACGTTC
TATCTCCAAACGTGCTGAAGACTTCCTGAAATCTTCAGGTATCGCTGATACCGTGTTGTTCGGGCCAGAACCAGAATTCT
TCCTGTTTGACGATATCCGTTTTGGTAGCAGCATCAATGGGTCACACGTATCCATCGATGACGTCGAAGGCGCATGGAAC
TCCAGCACCAAATACGAAGGCGGCAACAAAGGCCACCGTCCTGCAGTAAAAGGCGGTTACTTCCCTGTTCCTCCGGTCGA
CTCTGCACAAGACCTCCGTTCTGCCATGTGTCTGACGATGGAAGAGATGGGCTTGGTGGTAGAAGCACACCACCACGAAG
TGGCTACCGCGGGTCAAAACGAAGTGGCTACCCGCTTCAATACCATGACCAAGAAAGCAGATGAGATCCAGATTTACAAA
TACGTCGTACACAACGTGGCGCACGCATTTGGTAAAACAGCGACCTTTATGCCAAAACCGATGTTCGGCGATAACGGCTC
AGGTATGCACTGCCATATGTCTTTGTCCAAGAACGGTAATAACCTGTTCGCTGGCGACAAATACGGCGGCCTGTCTGAAA
TCGCCCTGTTCTACATCGGCGGTATCATCAAACATGCGAAAGCCATTAATGCCTTGGCTAACCCGACCACCAACTCCTAC
AAGCGTCTGGTCCCAGGTTATGAAGCACCGGTCATGCTGGCATATTCAGCCCGTAACCGTTCAGCTTCTATCCGTATTCC
TGTTGTTGCCAGCCCGAAAGCTCGCCGTATTGAAGCGCGTTTCCCCGATCCTGCGGCTAACCCGTACCTGTGCTTCGCCG
CGCTGTTGATGGCTGGCCTTGATGGCATCATCAACAAAATTCACCCAGGTGATGCGATGGACAAAAACCTGTATGACTTG
CCGCCGGAAGAAGAAGCTGAGATTCCAAAAGTTGCCGGTTCACTGGACGAAGCCATGGCCGCATTGAACGAAGATCGCGA
GTTCCTGACTCGTGGTGGCGTGTTCACCGATGATGCTATCGATGCGTATATCGAGCTACGTAGAGAAGAAATGGATCGCG
TGCGTATGACTCCGCATCCTGTTGAGTTCGAACTGTATTACAGCGTTTAA

Protein sequence :
MSAEHVLTMLNEHEVKFVDLRFTDTKGKEQHITIPAHQVNADFFEEGKMFDGSSIGGWKGINESDMVLMPDASTAVMDPF
FADSTLIIRCDILEPGTMQGYDRDPRSISKRAEDFLKSSGIADTVLFGPEPEFFLFDDIRFGSSINGSHVSIDDVEGAWN
SSTKYEGGNKGHRPAVKGGYFPVPPVDSAQDLRSAMCLTMEEMGLVVEAHHHEVATAGQNEVATRFNTMTKKADEIQIYK
YVVHNVAHAFGKTATFMPKPMFGDNGSGMHCHMSLSKNGNNLFAGDKYGGLSEIALFYIGGIIKHAKAINALANPTTNSY
KRLVPGYEAPVMLAYSARNRSASIRIPVVASPKARRIEARFPDPAANPYLCFAALLMAGLDGIINKIHPGDAMDKNLYDL
PPEEEAEIPKVAGSLDEAMAALNEDREFLTRGGVFTDDAIDAYIELRREEMDRVRMTPHPVEFELYYSV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
glnA YP_003728749.1 glutamine synthetase Not tested cag PAI Protein 3e-99 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
glnA YP_002345120.1 glutamine synthetase VFG1399 Protein 4e-115 51