Gene Information

Name : nrdE (YPO2649)
Accession : YP_002347601.1
Strain : Yersinia pestis CO92
Genome accession: NC_003143
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 2976950 - 2979031 bp
Length : 2082 bp
Strand : -
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
ATGCTGAACCTTTATGATGCTGATGGGCGTATCCAGTTTGATAAAGACCGGCTGGCCGCACGGCAATACTTTTTGCAGCA
CGTTAATCAAAACACGGTGTTCTTCCATAATCTACAGGAAAAAATTGATTACCTGATTGAGGAGGGATATTACGAAAAAG
AGGTTCTGGATCAATACGATTTTAGCTTTATCAAAAGTCTATTCCAGCAAGCCTATAGCAAAAAATTTCGTTTCCCCACT
TTTCTCGGGGCGTTTAAATATTACACCAGCTACACCCTAAAAACCTTTGATGGCAAACGTTACCTGGAACGCTATGAAGA
TCGCGTTTGCATGGTCGCACTGACACTGGCTACAGGTAACCAGACACTGGCGCGGGAACTGGTAGAAGAAATTATCTCTG
GCCGCTTCCAACCCGCCACACCAACCTTCCTCAATTGTGGCAAAAAACAACGTGGTGAACTGGTCTCCTGCTTCCTGTTG
CGTATCGAAGACAATATGGAATCCATTGGCCGCTCGATTAACTCGGCACTGCAACTCTCTAAACGTGGCGGAGGCGTGGC
GTTCCTCCTCAGCAATATCCGTGAGGTGGGTGCTCCCATCAAACGGATTGAAAATCAGTCTTCGGGTGTTATCCCGATAA
TGAAAATGTTGGAGGACGCGTTCTCCTATGCCAATCAGTTGGGTGCCCGTCAGGGGGCGGGGGCGGTCTATCTCCATGCC
CATCATCCAGATATTTTGCGTTTTCTGGATACCAAGCGGGAAAATGCCGATGAAAAAGTACGGATTAAGACCTTATCGTT
GGGGGTGGTGATACCGGATATCACTTTTGAACTGGCGAAGAATAATGAAGAAATGTACCTGTTTTCACCTTATGACATTG
AACAGGTTTACGGCGTGCCCATGTCTGAAATCAGCATCAGCGAAAAATACCGCGAAATGGTGGATAACAAACGCATCCGC
AAAAGCAAAATTAAAGCCCGCGAGTTCTTCCAAATTCTGGCTGAGATCCAATTTGAATCTGGCTACCCTTATATGATGTT
TGAAGATACGGTTAATCGCGCTAATCCGATTAAAGGCCGGATTAATATGAGTAATTTGTGTTCGGAAATTTTGCAGGTCA
ACGCCCCCACTGAATACCACGAAGACCTCAGCTATCGCCGTATCGGGAAAGATATCTCCTGTAATCTTGGCTCGCTGAAT
ATCGCGCAGGTGATGGATTCACCCGATTTTGGTAAATCCATTGAGATCGCCATTCGTGGGCTCACTGCCGTATCTGAAAT
GAGCAATATTCGCTCAGTGCCATCCATTGAAAAAGGCAATCAAGAATCACATGCCATTGGCCTTGGGCAGATGAACCTGC
ACGGTTATCTGGCGCGGGAGCGTCTTTTTTACGGCTCGGAAGAGGCGTTGGATTTTACCAATATCTATTTTTATACCGTG
GCGTATCACGCGATCCGTGCCTCAAACCAGTTGGCAATAGAACGGGCCAGCCATTTCAAAGGCTTCGATGAATCAGATTA
TGCTTCGGGTGCTTTCTTCAGCAAATATATCGAGCAAAGCTGGCAGCCAAAAACAGCAAGAGTACAGGCACTGTTTGCCG
ATGCCGGTATTGCCATACCAAACCAACAAGATTGGATCGCGCTACGGCAATCCGTTATGGAACACGGTATTTATAATCAG
AACCTACAGGCGGTGCCACCAACAGGCTCTATTTCCTATATCAATCATTCGACATCAAGTATCCACCCGATTGTCTCTCC
GATTGAGATCCGTAAAGAAGGCAAAATAGGCCGTGTTTATTATCCCGCACCCTATATGACCAACGATAACCTTGAATATT
ATCAAGATGCCTACCAGATCGGGCCTGAAAAAATCATCGATACCTATGCCGCAGCGACCCAACATGTTGATCAGGGCCTC
TCTCTGACGCTGTTCTTCCGTGATACCGCTACCACCCGCGATATTAACAAAGCACAGATTTACGCTTGGAAGAAAGGGAT
CAAGACCATTTATTACATCCGGCTACGTCAGATGGCATTAGAGGGAACCGAAGTCGAGGGCTGCGTTTCCTGTTCGCTGT
AA

Protein sequence :
MLNLYDADGRIQFDKDRLAARQYFLQHVNQNTVFFHNLQEKIDYLIEEGYYEKEVLDQYDFSFIKSLFQQAYSKKFRFPT
FLGAFKYYTSYTLKTFDGKRYLERYEDRVCMVALTLATGNQTLARELVEEIISGRFQPATPTFLNCGKKQRGELVSCFLL
RIEDNMESIGRSINSALQLSKRGGGVAFLLSNIREVGAPIKRIENQSSGVIPIMKMLEDAFSYANQLGARQGAGAVYLHA
HHPDILRFLDTKRENADEKVRIKTLSLGVVIPDITFELAKNNEEMYLFSPYDIEQVYGVPMSEISISEKYREMVDNKRIR
KSKIKAREFFQILAEIQFESGYPYMMFEDTVNRANPIKGRINMSNLCSEILQVNAPTEYHEDLSYRRIGKDISCNLGSLN
IAQVMDSPDFGKSIEIAIRGLTAVSEMSNIRSVPSIEKGNQESHAIGLGQMNLHGYLARERLFYGSEEALDFTNIYFYTV
AYHAIRASNQLAIERASHFKGFDESDYASGAFFSKYIEQSWQPKTARVQALFADAGIAIPNQQDWIALRQSVMEHGIYNQ
NLQAVPPTGSISYINHSTSSIHPIVSPIEIRKEGKIGRVYYPAPYMTNDNLEYYQDAYQIGPEKIIDTYAAATQHVDQGL
SLTLFFRDTATTRDINKAQIYAWKKGIKTIYYIRLRQMALEGTEVEGCVSCSL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 0.0 76