Gene Information

Name : yscN (YPCD1.40)
Accession : NP_395174.1
Strain :
Genome accession: NC_003131
Putative virulence/resistance : Virulence
Product : type III secretion system ATPase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 28186 - 29505 bp
Length : 1320 bp
Strand : +
Note : Yops secretion protein

DNA sequence :
ATGCTCTCACTAGATCAGATACCTCATCATATTCGTCATGGCATTGTAGGTAGCCGCCTAATCCAAATTAGAGGACGTGT
CACTCAAGTGACAGGAACGTTATTAAAAGCGGTAGTGCCAGGTGTGCGCATCGGTGAGTTATGTTACTTACGTAACCCTG
ACAACAGCCTGTCTTTACAGGCTGAAGTCATAGGTTTTGCCCAACATCAAGCATTACTTATTCCACTTGGTGAAATGTAC
GGGATATCTTCTAATACTGAAGTTAGCCCGACAGGGACAATGCATCAGGTTGGGGTGGGTGAACATCTGCTGGGACAGGT
GTTGGATGGTTTAGGGCAGCCTTTCGATGGGGGGCATCTCCCTGAACCGGCGGCTTGGTACCCAGTTTATCAGGATGCCC
CAGCGCCGATGAGCCGAAAACTTATTACCACACCACTTTCTTTGGGGATCCGGGTTATTGACGGTTTGCTTACCTGTGGC
GAGGGGCAAAGAATGGGCATCTTCGCGGCCGCCGGGGGGGGGAAAAGTACACTGCTTGCTTCGCTTATTCGTAGTGCTGA
AGTAGACGTAACCGTGCTGGCGCTTATTGGTGAGCGTGGACGCGAAGTGCGTGAGTTTATTGAGTCTGATTTAGGCGAAG
AGGGGTTACGCAAAGCGGTTCTCGTGGTGGCCACCTCGGATCGGCCCTCAATGGAAAGAGCCAAAGCTGGATTCGTGGCG
ACATCTATTGCTGAATATTTTCGCGATCAAGGGAAACGCGTATTGTTACTTATGGACTCTGTAACACGGTTTGCTCGTGC
TCAGCGTGAAATAGGCTTAGCTGCGGGAGAACCACCGACTCGCCGCGGTTATCCTCCGTCAGTATTTGCCGCTTTACCCC
GTTTGATGGAAAGGGCTGGTCAGTCCAGCAAAGGGTCAATTACGGCTCTCTATACCGTACTGGTCGAAGGGGACGATATG
ACCGAACCCGTGGCCGACGAAACACGTTCGATACTTGATGGTCATATTATTCTGTCACGGAAATTAGCGGCAGCTAATCA
TTATCCTGCCATTGACGTATTACGTTCAGCGAGCAGGGTGATGAATCAAATTGTCAGCAAGGAGCACAAAACCTGGGCGG
GGGACTTACGCCGTTTATTGGCCAAATATGAAGAAGTGGAATTGCTGTTGCAAATCGGGGAGTACCAGAAAGGGCAAGAC
AAAGAGGCCGATCAAGCGATTGAACGCATGGGGGCGATTCGAGGATGGCTCTGCCAGGGGACGCACGAGTTAAGCCATTT
CAATGAGACGCTGAACTTATTGGAGACGCTGACCCAATGA

Protein sequence :
MLSLDQIPHHIRHGIVGSRLIQIRGRVTQVTGTLLKAVVPGVRIGELCYLRNPDNSLSLQAEVIGFAQHQALLIPLGEMY
GISSNTEVSPTGTMHQVGVGEHLLGQVLDGLGQPFDGGHLPEPAAWYPVYQDAPAPMSRKLITTPLSLGIRVIDGLLTCG
EGQRMGIFAAAGGGKSTLLASLIRSAEVDVTVLALIGERGREVREFIESDLGEEGLRKAVLVVATSDRPSMERAKAGFVA
TSIAEYFRDQGKRVLLLMDSVTRFARAQREIGLAAGEPPTRRGYPPSVFAALPRLMERAGQSSKGSITALYTVLVEGDDM
TEPVADETRSILDGHIILSRKLAAANHYPAIDVLRSASRVMNQIVSKEHKTWAGDLRRLLAKYEEVELLLQIGEYQKGQD
KEADQAIERMGAIRGWLCQGTHELSHFNETLNLLETLTQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 6e-176 88
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-114 61
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 4e-115 61
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-114 61
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-114 61
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-114 61
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-115 61
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 3e-114 61
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 2e-114 61
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 4e-115 61
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 6e-100 57
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 3e-100 57
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-100 57
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 2e-100 57
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-100 57
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 4e-100 57
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 2e-86 54
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 8e-93 54
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 1e-88 53
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 1e-91 53
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 8e-92 53
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 5e-92 53
escN YP_003236088.1 translocator EscN Virulence LEE Protein 1e-96 52
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 6e-97 52
escN CAC81862.1 EscN protein Virulence LEE II Protein 5e-97 52
escN YP_003223475.1 translocator EscN Virulence LEE Protein 6e-97 52
escN CAI43874.1 EscN protein Virulence LEE Protein 4e-97 52
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 5e-88 52
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 5e-88 52
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 2e-97 52
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 2e-88 51
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-93 51
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-93 51
unnamed AAL06369.1 EscN Virulence LEE Protein 5e-96 51
escN AAL57542.1 EscN Virulence LEE Protein 1e-96 51
escN AAC38383.1 EscN Virulence LEE Protein 5e-96 51
escN AAC31513.1 L0034 Virulence LEE Protein 4e-96 51
escN NP_290268.1 hypothetical protein Virulence LEE Protein 5e-96 51
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 4e-96 51
ECs4568 NP_312595.1 EscN Virulence LEE Protein 5e-96 51
escN AAK26715.1 EscN Virulence LEE Protein 1e-96 51
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 3e-84 51
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 3e-84 51
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 2e-78 48
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-84 47
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 1e-84 47
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-84 47
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-84 47
invC AAS66861.1 InvC Not tested SSR-2 Protein 4e-82 47
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 3e-82 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
yscN NP_395174.1 type III secretion system ATPase VFG0390 Protein 0.0 100
yscN NP_395174.1 type III secretion system ATPase VFG0192 Protein 4e-169 84
yscN NP_395174.1 type III secretion system ATPase VFG0048 Protein 9e-138 69
yscN NP_395174.1 type III secretion system ATPase VFG0515 Protein 2e-100 57
yscN NP_395174.1 type III secretion system ATPase VFG2144 Protein 8e-110 56
yscN NP_395174.1 type III secretion system ATPase VFG0812 Protein 2e-96 51
yscN NP_395174.1 type III secretion system ATPase VFG0730 Protein 3e-96 51
yscN NP_395174.1 type III secretion system ATPase VFG0555 Protein 5e-85 47
yscN NP_395174.1 type III secretion system ATPase VFG1254 Protein 5e-83 47
yscN NP_395174.1 type III secretion system ATPase VFG2459 Protein 1e-84 46
yscN NP_395174.1 type III secretion system ATPase VFG2331 Protein 4e-74 45
yscN NP_395174.1 type III secretion system ATPase VFG1008 Protein 1e-78 45
yscN NP_395174.1 type III secretion system ATPase VFG1778 Protein 5e-83 45
yscN NP_395174.1 type III secretion system ATPase VFG2499 Protein 2e-75 44