Gene Information

Name : NMA1012 (NMA1012)
Accession : YP_002342432.1
Strain : Neisseria meningitidis Z2491
Genome accession: NC_003116
Putative virulence/resistance : Unknown
Product : carbon-sulfur lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.-
Position : 975578 - 976735 bp
Length : 1158 bp
Strand : -
Note : NMA1012, probable carbon-sulphur lyase, len: 385 aa; similar to many members of the pyridoxal-phosphate dependent cysteine and methionine metabolism family e.g. SW:MEGL_PSEPU (EMBL:D88554), mdeA, Pseudomonas putida methionine gamma-lyase (EC 4.4.1.11) (39

DNA sequence :
ATGAAATTCGCCACGAAAGCCATTCATTCCAGCTACGATTGCGACGAACACAACCGCGCGCTGATGCCGCCGATTTATCA
AAACAGTATGTTCGCGTTGCACGAGATTGGCGAAAATGTGCCTTACCGCTACTCGCGCCTGAGCAACCCGACCCGTCAGA
TTTTAGAAGACACCGTTGCCGATTTGGAACACGGTGCGGCAGGTTTTGCGTTTTCCAGCGGTATGGCGGGGATTGATGCC
GTGTGGCGTACCTTCCTACAACCGGGCGATACCATCGTCGCGGTCGCCGATATTTACGGCGGCGCGTATGATTTATTGGT
CGATGTTTATCAAAAATGGGGGGTGAACGTTGTTTTTGCCGATTTGGGCAATCCGGATAATTTGGACGAATTGCTCAAAG
CGCACAAGGTCAAACTGGTTTGGCTGGAAACGCCGTCCAATCCGCTTTTGCGCTTGGTAGACATCAAAGCGCTTGCCGCG
AAAGCCAAAGCGGCCGGCGCACTGGTCGGTATCGACAACACCTTTGCCACGCCGTATCTGCAACAGCCCTTGGATATGGG
TTGCGATTTTGTGTTCCATTCCGCTACCAAATATTTGTGCGGCCATTCCGACGTGTTGATGGGCATCGTCGTTGCCAAAA
CCAAAGAGCTGGCGCAGCCTTTGCACGATATGATGGTGCATACCGGCGCGGTTGCCGGCCCGATGGACTGCTGGCTGGTG
TTGCGCGGCATCAAAACACTGGCTCTGCGCATGAACGCCCATTACCAAAACGCACTCGAAATCGCGCGCCGTTTGGAAGC
CCATCCTGCCATTGAAAAAGTGTTCCATCCCGGCCTGCCGTCTCACGAACATTACGAACTGGCGAAAACACAAATGCCCA
AAGGCATAGGCGGCGTGGTTACGGTTTATCTCAAAAACGACACGCGTGAAGCGGCAAACAGCGTGATTAAAAACATGAAA
CTGGTCAAAATGGCTTCCAGCCTCGGCGGCGTGGAAAGTTTGGTCAACCATTGCTATTCCCAGTCCCACAGCGGCGTGCC
GCATAATGTGAAAATGGAAATGGGCATCAGGGTCGGCCTGCTGCGTTTCTCTGTCGGTATCGAAGATGTAGATGATATTT
GGAATGATATTTCCGCCGCACTCGATACAACTTTGTAA

Protein sequence :
MKFATKAIHSSYDCDEHNRALMPPIYQNSMFALHEIGENVPYRYSRLSNPTRQILEDTVADLEHGAAGFAFSSGMAGIDA
VWRTFLQPGDTIVAVADIYGGAYDLLVDVYQKWGVNVVFADLGNPDNLDELLKAHKVKLVWLETPSNPLLRLVDIKALAA
KAKAAGALVGIDNTFATPYLQQPLDMGCDFVFHSATKYLCGHSDVLMGIVVAKTKELAQPLHDMMVHTGAVAGPMDCWLV
LRGIKTLALRMNAHYQNALEIARRLEAHPAIEKVFHPGLPSHEHYELAKTQMPKGIGGVVTVYLKNDTREAANSVIKNMK
LVKMASSLGGVESLVNHCYSQSHSGVPHNVKMEMGIRVGLLRFSVGIEDVDDIWNDISAALDTTL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-60 44
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-61 44