Gene Information

Name : kdsB (NMA0875)
Accession : YP_002342308.1
Strain : Neisseria meningitidis Z2491
Genome accession: NC_003116
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 851876 - 852637 bp
Length : 762 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGACCGAATTCGTCGTATTGATTCCGGCGCGGCTGGATTCGTCGCGCCTGCCTGGAAAAGCCTTGGCGGACATCCACGG
CAAACCGATGGTCGTGCGCGTTGCCGAACAGGCGGCAAAAAGTAAAGCCGCGCGCGTCGTCGTCGCCACCGACCATCCCG
ATATTCAGACGGTCTGTCAGGCGCACGGCATCGAAGCGGTTATGACTTCAAACCGGCACGAAAGCGGCACGACGCGCCTT
GCTGAAGCTGCCGCCGCGCTGAAGCTGCCGCCGCATCTGGTGGTTGTCAACGTACAGGGCGACGAGCCGCTGATTGCCCC
CGAACTCATCGACCGCACCGCCGAAGTACTCGTCGAAAACAACGTCCAAATGGCGACCGCCGCCCACGAATTGCACGATT
TCGACGAATTGATGAATCCCAATGCCGTCAAAGTCGTCCTCGACAAAAACCGCAACGCCATCTACTTCAGCCGCGCCCCG
ATTCCCTATCCGCGCGATGCAATGCGTGCCGGAAAACGCGAAATGCCGTCTGAAACCGCCGTCCTGCGCCATATCGGCAT
CTACGCTTACCGCGCCGGCTTCCTGCAACGCTATGCCGAAATGAGCGTTTCGCCGCTGGAAACCATCGAATCGCTGGAAC
AGCTGCGCGTCCTGTGGCACGGTTATCCCATTGCCGTCGAAACCGCCAAAGAAGCCCCCGCCGCCGGTGTGGATACGCAG
GAAGATTTGGACAGGGTCCGCGCCGTATTTCAGACCGTATAA

Protein sequence : 
MTEFVVLIPARLDSSRLPGKALADIHGKPMVVRVAEQAAKSKAARVVVATDHPDIQTVCQAHGIEAVMTSNRHESGTTRL
AEAAAALKLPPHLVVVNVQGDEPLIAPELIDRTAEVLVENNVQMATAAHELHDFDELMNPNAVKVVLDKNRNAIYFSRAP
IPYPRDAMRAGKREMPSETAVLRHIGIYAYRAGFLQRYAEMSVSPLETIESLEQLRVLWHGYPIAVETAKEAPAAGVDTQ
EDLDRVRAVFQTV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 3e-29 43
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 2e-29 43
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 6e-30 43