Gene Information

Name : mutS (NMA0247)
Accession : YP_002341781.1
Strain : Neisseria meningitidis Z2491
Genome accession: NC_003116
Putative virulence/resistance : Virulence
Product : DNA mismatch repair protein MutS
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0249
EC number : -
Position : 231216 - 233810 bp
Length : 2595 bp
Strand : +
Note : This protein performs the mismatch recognition step during the DNA repair process

DNA sequence :
ATGTCCAAATCCGCCGTTTCCCCAATGATGCAGCAATACCTCGGCATCAAAGCGCAACATACCGACAAACTGGTGTTTTA
CCGTATGGGCGATTTTTACGAGATGTTTTTCGACGATGCGGTAGAAGCGGCAAAACTTTTGGATATTACCCTGACCACGC
GCGGACAGGTGGATGGCGAGCCGGTCAAAATGGCAGGCGTGCCGTTTCACGCCGCCGAACAATATCTGGCGCGCCTGGTC
AAGTTGGGCAAAAGCGTGGCGATTTGCGAACAGGTCGGCGAAGTCGGCGCGGGCAAAGGGCCTGTGGAGCGCAAAGTCGT
GCGCATCGTAACGCCCGGCACGCTGACCGATTCCGCATTGCTGGAAGACAAGGAAACCAACCGTATCGTTGCCGTGTCCC
CCGACAAAAAATACATCGGTTTGGCGTGGGCATCGCTGCAAAGCGGCGAATTCAAAACCAAGCTGACAACTGTGGATAAA
TTGGACGACGAACTGGCGCGCCTGCAGGCGGCGGAAATTCTGTTGCCGGACAGTAAAAACGCACCGCAACTTCAGACGGC
ATCGGGTGTTACGCGCCTGAACGCGTGGCAGTTTGCCGCCGACGCGGGGGAAAAACTGCTGACGGAATATTTCGGCTGCC
AGGATTTGCGCGGCTTCGGTTTGGACGGCAAAGAACACGCCGTTGCGATTGGCGCGGCAGGTGCACTGTTGAACTATATC
CGTCTGACGCAAAACCTGATGCCGCAACATTTGGACGGCCTGTCGCTCGAAACCGACAGCCAATATATCGGTATGGATGC
TGCCACGCGCCGCAATCTCGAAATCACGCAAACCCTCTCCGGCAAAAAATCGCCGACCCTGATGTCCACGCTCGACCTTT
GCGCTACCCATATGGGCAGCCGCCTCTTGGCTCTCTGGCTGCACCACCCTTTACGCAACCGCGCCCACATCCGAGCGCGC
CAAGAAGCCGTTGCCGCGCTGGAAAGCCAATACAAACCCCTCCAATGCCGTCTGAAAAACATTGCGGACATTGAACGCAT
TGCTGCCCGCATCGCCGTCGGCAACGCCCGCCCGCGCGATTTGGCATCTTTACGCGACAGTCTGTTCGAGTTGGCACAAA
TCGACTTGTCCGCAAACGGCAGCAGCCTGTTGGAAACCCTCAAAGCCGTTTTCCCGGAAAACCTATCCACAGCCGAACAG
CTCCGCCAAGCCATTTTGCCCGAACCTTCCGTCTGGCTGAAAGACGGCAATGTCATCAACCACGGTTTTCATCCCGAACT
GGACGAATTGCGCCGCATTCAAAACCATGGCGACGAATTTTTGCTGGATTTGGAAGCCAAGGAACGCGAACGTACCGGTT
TGTCCACACTCAAAGTCGAGTTCAACCGCGTTCACGGCTTTTACATTGAATTGTCCAAAACCCAAGCCGAACAAGCACCT
GCCGACTACCAACGCCGGCAAACCCTCAAAAACGCCGAACGCTTCATCACGCCGGAACTGAAAGCCTTTGAAGACAAAGT
GCTGACTGCTCAAGAGCAAGCCCTCGCCTTAGAAAAACAACTCTTTGACGGCGTATTGAAAAACCTTCAGACGGCATTGC
CGCAGCTTCAAAAAGCCGCCAAAGCCGCCGCCGCGCTGGACGTATTGTCCACATTTTCAGCCTTGGCAAAAGAGCGGAAC
TTCGTCCGCCCCGAGTTTGCCGACTATCCGGCTATCCACATCGAAAACGGTCGCCATCCCGTTGTCGAACAGCAGGTACG
CCACTTCACCGCCAACCACACCAACCTTGACCACAAACACCGCCTCATGCTGCTCACCGGCCCCAATATGGGCGGCAAAT
CCACCTACATGCGCCAAGTCGCGCTGATTGTTTTATTGGCACACACCGGCTGTTTTGTGCCTGCCGATGCCGCCACAATC
GGGCCCATCGATCAAATCTTCACCCGCATCGGCGCATCGGACGACCTCGCCTCCAACCGCTCCACTTTCATGGTCGAAAT
GAGCGAAACCGCCTACATCCTGCATCACGCCACCGAACAAAGCCTTGTTTTAATGGACGAAGTCGGACGTGGCACTTCCA
CTTTCGACGGCCTCGCCCTCGCGCACGCCGTTGCCGAACACCTGCTGCAAAAAAACAAATCCTTCAGCCTGTTTGCCACC
CACTATTTCGAGCTGACCTACCTGCCCGAAGCCCACGCCGCCGCCGTCAATATGCACCTTTCCGCGCTCGAACAGGGACA
GGACATCGTGTTTCTGCACCAAATCCAACCCGGTCCCGCCGGCAAAAGCTACGGCATCGCCGTTGCCAAACTCGCCGGCC
TGCCTGTACGCGCATTGAAATCCGCCCAAAAGCATTTGAACGGACTGGAAAACCAAGCCGCCGCGAACCGTCCCCAACTG
GATATTTTCAGTACCATGCCGTCTGAAAAAGGAGATGAACCGAATGTGGGCAACTTTGTGGATAAAGCAGAGGAAAAACA
TTTTGAAGGTATATTGGCAGCAGCCTTGGAAAAACTCGATCCCGACAGCCTGACCCCGCGCGAAGCATTGTCAGAACTGT
ACCGTCTGAAAGATTTGTGCAAATCCGTATCTTAA

Protein sequence :
MSKSAVSPMMQQYLGIKAQHTDKLVFYRMGDFYEMFFDDAVEAAKLLDITLTTRGQVDGEPVKMAGVPFHAAEQYLARLV
KLGKSVAICEQVGEVGAGKGPVERKVVRIVTPGTLTDSALLEDKETNRIVAVSPDKKYIGLAWASLQSGEFKTKLTTVDK
LDDELARLQAAEILLPDSKNAPQLQTASGVTRLNAWQFAADAGEKLLTEYFGCQDLRGFGLDGKEHAVAIGAAGALLNYI
RLTQNLMPQHLDGLSLETDSQYIGMDAATRRNLEITQTLSGKKSPTLMSTLDLCATHMGSRLLALWLHHPLRNRAHIRAR
QEAVAALESQYKPLQCRLKNIADIERIAARIAVGNARPRDLASLRDSLFELAQIDLSANGSSLLETLKAVFPENLSTAEQ
LRQAILPEPSVWLKDGNVINHGFHPELDELRRIQNHGDEFLLDLEAKERERTGLSTLKVEFNRVHGFYIELSKTQAEQAP
ADYQRRQTLKNAERFITPELKAFEDKVLTAQEQALALEKQLFDGVLKNLQTALPQLQKAAKAAAALDVLSTFSALAKERN
FVRPEFADYPAIHIENGRHPVVEQQVRHFTANHTNLDHKHRLMLLTGPNMGGKSTYMRQVALIVLLAHTGCFVPADAATI
GPIDQIFTRIGASDDLASNRSTFMVEMSETAYILHHATEQSLVLMDEVGRGTSTFDGLALAHAVAEHLLQKNKSFSLFAT
HYFELTYLPEAHAAAVNMHLSALEQGQDIVFLHQIQPGPAGKSYGIAVAKLAGLPVRALKSAQKHLNGLENQAAANRPQL
DIFSTMPSEKGDEPNVGNFVDKAEEKHFEGILAAALEKLDPDSLTPREALSELYRLKDLCKSVS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
mutS AAA80578.1 DNA mismatch repair protein Virulence SPI-1 Protein 2e-168 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mutS YP_002341781.1 DNA mismatch repair protein MutS VFG0562 Protein 1e-178 50