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Name : NMA2179 (NMA2179) Accession : YP_002343426.1 Strain : Neisseria meningitidis Z2491 Genome accession: NC_003116 Putative virulence/resistance : Resistance Product : dihydrofolate reductase Function : - COG functional category : H : Coenzyme transport and metabolism COG ID : COG0262 EC number : 1.5.1.3 Position : 2126278 - 2126766 bp Length : 489 bp Strand : - Note : NMA2179, folA, dihydrofolate reductase, len: 162aa; similar to many eg. SW:P12833 (DYR3_SALTY) dhfrIII,dihydrofolate reductase type III from Salmonella typhimurium (162 aa) fasta scores; E(): 2.1e-26, 50.7% identity in 152 aa overlap. Contains Pfam match DNA sequence : ATGCTCAAAATAACCCTAATTGCGGCGTGTGCGGAAAACCTGTGCATCGGGGCGGGCAATGCTATGCCTTGGCACATCCC CGAAGATTTCGCATTTTTCAAAGCCTATACCTTGGGCAAACCCGTCATTATGGGGCGGAAAACGTGGGAATCCCTGCCCG TCAAACCCCTGCCTGGACGGAGGAACATCGTCATCAGCCGGCAGGCGGATTATTGCGCGGCAGGCGCGGAAACGGCGGCA AGTTTGGAGGCGGCATTGGCATTGTGCGCAGGCGCGGAAGAAGCCGTCATTATGGGCGGCGCGCAGATATACGGACAAGC GATGCCATTGGCGACCGATTTGCGGATAACCGAAGTGGATTTGTCTGTGGAAGGAGATGCATTTTTCCCCGCAATAGACC GGACGCATTGGAAAGAAGCAGAGCGGACGGAACGCCGTGTCAGCAGCAAAGGCACGAGCTATGCTTTTGTGCATTATTTG AGATATTGA Protein sequence : MLKITLIAACAENLCIGAGNAMPWHIPEDFAFFKAYTLGKPVIMGRKTWESLPVKPLPGRRNIVISRQADYCAAGAETAA SLEAALALCAGAEEAVIMGGAQIYGQAMPLATDLRITEVDLSVEGDAFFPAIDRTHWKEAERTERRVSSKGTSYAFVHYL RY |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| dfrA12 | ACF06156.1 | dihydrofolate reductase | Not tested | Tn5036-like | Protein | 1e-15 | 44 |
