Gene Information

Name : NMA2128 (NMA2128)
Accession : YP_002343377.1
Strain : Neisseria meningitidis Z2491
Genome accession: NC_003116
Putative virulence/resistance : Virulence
Product : glutamine synthetase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0174
EC number : 6.3.1.2
Position : 2077423 - 2078841 bp
Length : 1419 bp
Strand : -
Note : NMA2128, glnA, glutamine synthetase, len: 472aa; strongly similar to many eg. TR:P95395 (EMBL:U82856) glnA,glutamine synthetase from Neisseria meningitidis strain M470 (468 aa) fasta scores; E(): 0, 99.6% identity in 468 aa overlap. Contains Pfam match to

DNA sequence :
ATGTCTATTAAAAACGCCGTAAAATTGATTGAAGAAAGCGAAGCCCGCTTTGTCGATTTGCGCTTTACCGATACCAAAGG
CAAGCAGCACCACTTTACCGTGCCTGCGCGCATCGTGTTGGAAGACCCCGAAGAGTGGTTTGAAAACGGTCAGGCGTTTG
ACGGTTCGTCTATCGGCGGCTGGAAAGGCATTCAGGCTTCCGATATGCAGTTGCGTCCCGATGCGTCTACGGCCTTCGTC
GATCCTTTTTATGATGATGCGACTGTTGTGTTGACTTGCGACGTTATCGATCCCGCCGACGGTCAGGGTTACGACCGCGA
CCCGCGCTCCATCGCACGCCGCGCCGAGGCCTATTTGAAATCTTCCGGTATCGGCGACACGGCATACTTCGGCCCCGAGC
CTGAATTCTTCGTCTTCGACGGCGTAGAATTTGAAACCGACATGCACAAAACCCGTTACGAAATCACGTCCGAAAGCGGC
GCATGGGCAAGCGGCCTGCACATGGACGGTCAAAACACCGGCCACCGCCCTGCCGTTAAAGGCGGTTACGCGCCCGTTGC
TCCGATTGACGCGGGACAAGACCTGCGCTCCGCGATGGTAAACATTTTGGAAGAACTCGGCATCGAAGTCGAAGTCCACC
ACAGTGAAGTCGGTACCGGCAGCCAAATGGAAATCGGCACGCGTTTCGCCACCTTGGTCAAACGCGCCGACCAAACCCAA
GACATGAAATATGTGATTCAAAACGTTGCCCACAACTTCGGCAAAACCGCCACTTTCATGCCCAAACCCATTATGGGCGA
CAACGGCAGCGGTATGCACGTTCACCAATCCATCTGGAAAGACGGTCAAAACCTGTTCGCCGGCGACGGCTATGCCGGTT
TGAGCGACACCGCCCTTTATTACATCGGCGGCATCATCAAACACGCCAAAGCCCTGAACGCGATTACCAATCCGTCCACC
AACTCCTACAAACGCCTCGTGCCGCACTTTGAAGCGCCGACCAAACTCGCCTACTCCGCCAAAAACCGTTCCGCTTCCAT
CCGCATTCCGTCCGTGAACAGCAGCAAGGCGCGCCGCATCGAAGCGCGTTTCCCCGATCCGACCGCCAACCCATACTTGG
CGTTCGCCGCTTTGTTGATGGCCGGTTTGGACGGTATTCAAAACAAAATCCATCCGGGCGATCCTGCCGATAAAAACCTC
TACGATCTGCCGCCGGAAGAAGATACATTGGTGCCGACCGTTTGCGCTTCTTTGGAAGAAGCACTCGCCGCCCTCAAGGC
CGACCACGAATTCCTCCTGCGCGGCGGCGTGTTCAGCAAAGACTGGATCGACAGCTACATCGCTTTCAAAGAAGAAGACG
TACGCCGCATCCGCATGGCACCTCACCCGCTGGAATTTGAAATGTATTACAGCCTGTAA

Protein sequence :
MSIKNAVKLIEESEARFVDLRFTDTKGKQHHFTVPARIVLEDPEEWFENGQAFDGSSIGGWKGIQASDMQLRPDASTAFV
DPFYDDATVVLTCDVIDPADGQGYDRDPRSIARRAEAYLKSSGIGDTAYFGPEPEFFVFDGVEFETDMHKTRYEITSESG
AWASGLHMDGQNTGHRPAVKGGYAPVAPIDAGQDLRSAMVNILEELGIEVEVHHSEVGTGSQMEIGTRFATLVKRADQTQ
DMKYVIQNVAHNFGKTATFMPKPIMGDNGSGMHVHQSIWKDGQNLFAGDGYAGLSDTALYYIGGIIKHAKALNAITNPST
NSYKRLVPHFEAPTKLAYSAKNRSASIRIPSVNSSKARRIEARFPDPTANPYLAFAALLMAGLDGIQNKIHPGDPADKNL
YDLPPEEDTLVPTVCASLEEALAALKADHEFLLRGGVFSKDWIDSYIAFKEEDVRRIRMAPHPLEFEMYYSL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
glnA YP_003728749.1 glutamine synthetase Not tested cag PAI Protein 2e-96 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
NMA2128 YP_002343377.1 glutamine synthetase VFG1399 Protein 9e-102 50