Gene Information

Name : NMA0186 (NMA0186)
Accession : YP_002341732.1
Strain : Neisseria meningitidis Z2491
Genome accession: NC_003116
Putative virulence/resistance : Virulence
Product : capsule polysaccharide modification protein
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG3563
EC number : -
Position : 168947 - 171061 bp
Length : 2115 bp
Strand : -
Note : NMA0186, lipA, capsule polysaccharide modification protein, len: 704 aa; almost identical to, but longer than, LIPA_NEIME Q05013 capsule polysaccharide modification protein (400 aa), fasta scores; E(): 0, 97.1% identity in 383 aa overlap, and similar to e

DNA sequence :
ATGTTCCTCTTTTCAGACGGCCTACAATCTATTAATAACAATAATCGACGAAAACGCATTGTGAAAAACGCCTACATCCC
CTCTCGCGGCATCCGCAAAATCCCCCATCTCTCCACCCTATTGCCCGAGTTTCATATCTACAAAGACGGAAAAGGAGCAG
AGGCTGTTGTCGGCTGGGGTTTGCGCCCGACGACACACAAAGCGCGTGCTTTTGCCACCGAACACCAGCTTCCCTTTATT
GCTTTGGAAGACGGCTTTTTACGCTCGCTCGGACTGGGCGTCTCCGGTTATCCCCCCTACTCCATCGTCTATGACGACAT
CGGCATCTACTACGACACTACCCGCCCTTCTCGTTTGGAACAACTGATTCTTGCCGCCGATACCATGCCGTCTGAAACCT
TGGCTCAGGCGCGGCAGGCGATGGATTTCATCCTGCAACACCATCTGTCCAAATACAACCACGCGCCCGAACTTTCAGAC
GATCATCCTTTACGCTCCCCATCCAAGTCTGAAACCGTCCTCATTATCGACCAAACCTTCGGCGATATGGCTATCCAATA
TGGCGGTGCAGACGCCTCTACGTTTGAATTGATGTTTCAGACGGCCTTAAATGAAAACCCGCAAGCCGATATTTGGGTCA
AAACCCATCCCGATGTTTTGTGCGGCAAAAAACAAGGCTATCTGACCCAGCTTGTGCAGCAACACCGCGTCCATCTTCTG
GCAGAAGACATCAATCCGATTTCTTTGTTGCAAAACGTCGATAAAGTTTATTGCGTTACCTCGCAAATGGGTTTTGAGGC
GCTTTTGTGCGGCAAGCCGCTGACCACTTTCGGCCTGCCGTGGTATGCCGGATGGGGCGTGAGTGACGACCGCCACCCAA
AAATCGGCAGCCTTATTCAAACCCAACGCCGCGCCCCCCGCAACTTGCTGCAACTCTTCGCCGCAGCCTATCTGCAATAC
AGCCGCTACCTCAATCCCAATACCGGCGAAGCAGGCAGCCTCTTTGATGTCATCGACTATCTGGCGACGGTCAAACGTAA
AAACGACAAATTGCGTGGCGAGTTATATTGCGTCGGTATGTCTTTGTGGAAACGCGCGGTTGCCAAACCGTTCTTTAACG
TACCCTCTTGCCGTCTGAAATTTATCTCTTCCACCCAAAAACTGGCAAGGGTCAAACTGTCCGACGATGCACGCATCCTG
GCTTGGGGCAACGGCAAAGAGGCCATCGTCCGCTTTGCCGAACAACACCACATCCCCCTGCTGCGCATGGAAGACGGCTT
TATCCGCTCGGTCGGACTCGGCTCCAACTTAGTGCCGCCGCTGTCGCTCGTTACCGACGATATGAGCATTTATTTCAATG
CCGAAACCCCGTCCCGTCTTGAATACATCCTACAAAACCAAAACTTCGACGATCAAGACTTTCAGACGGCCTTGAAGCTG
CAAAAAATGCTGACCGAAAACCACATCAGTAAATACAACGTCGGCAGCTCAGACTTCACCGCCCCGTCAACCGACAAAAC
CGTGATCCTCGTTCCCGGCCAGGTTGAAGATGATGCGTCTATCCGCTACGGTTCGCCCCAAATCTACCGCAATCTGGATT
TGCTCCGTACCGTACGCGAACGAAACCCCAATGCCTATATCATCTACAAACCGCATCCCGATGTAGTCAGCGGTAACCGC
ATCGGCCATATTTCCCCTGATGATGCTGCACGATATGCCGACCAAACCGCCGAACAAGCCGACATCCTGACCTGTCTCCA
ATACGCAGACGAAATACATACCATGACTTCGCTGACCGGTTTTGAAGCCTTGTTGCGCGGCAAAAAAGTCAGCTGCTACG
GCCTGCCTTTCTATGCAGGTTGGGGGCTTACCCAAGATCTGCTCCCTATTCCGCGCCGCAGCCGCAGGCTTGAGCTTTGG
CAGCTGGTTGCCGGCACGCTCATCTACTATCCCGACTACATCCACCCCAAAACCCATCAGGCCATCAATGCGGAAACTGC
AGCCCAAATCCTGATACGACAAAAAAATATGCAAAAAAACAACAACGGATTACATCGCGGGTGCTTTGCAAAAAAATTAG
GTAAAATCAAACAACTATATCGATCTTTCAAATAA

Protein sequence :
MFLFSDGLQSINNNNRRKRIVKNAYIPSRGIRKIPHLSTLLPEFHIYKDGKGAEAVVGWGLRPTTHKARAFATEHQLPFI
ALEDGFLRSLGLGVSGYPPYSIVYDDIGIYYDTTRPSRLEQLILAADTMPSETLAQARQAMDFILQHHLSKYNHAPELSD
DHPLRSPSKSETVLIIDQTFGDMAIQYGGADASTFELMFQTALNENPQADIWVKTHPDVLCGKKQGYLTQLVQQHRVHLL
AEDINPISLLQNVDKVYCVTSQMGFEALLCGKPLTTFGLPWYAGWGVSDDRHPKIGSLIQTQRRAPRNLLQLFAAAYLQY
SRYLNPNTGEAGSLFDVIDYLATVKRKNDKLRGELYCVGMSLWKRAVAKPFFNVPSCRLKFISSTQKLARVKLSDDARIL
AWGNGKEAIVRFAEQHHIPLLRMEDGFIRSVGLGSNLVPPLSLVTDDMSIYFNAETPSRLEYILQNQNFDDQDFQTALKL
QKMLTENHISKYNVGSSDFTAPSTDKTVILVPGQVEDDASIRYGSPQIYRNLDLLRTVRERNPNAYIIYKPHPDVVSGNR
IGHISPDDAARYADQTAEQADILTCLQYADEIHTMTSLTGFEALLRGKKVSCYGLPFYAGWGLTQDLLPIPRRSRRLELW
QLVAGTLIYYPDYIHPKTHQAINAETAAQILIRQKNMQKNNNGLHRGCFAKKLGKIKQLYRSFK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lipA NP_273145.1 capsule polysaccharide modification protein Not tested IHT-A Protein 0.0 98
kpsC YP_854335.1 capsule polysaccharide export protein KpsC Not tested PAI I APEC-O1 Protein 9e-134 50
kpsC AAZ04470.1 capsule polysaccharide export protein Virulence PAI I APEC-O1 Protein 7e-134 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
NMA0186 YP_002341732.1 capsule polysaccharide modification protein VFG0259 Protein 0.0 98
NMA0186 YP_002341732.1 capsule polysaccharide modification protein VFG0704 Protein 4e-157 58
NMA0186 YP_002341732.1 capsule polysaccharide modification protein VFG0692 Protein 3e-180 58