Gene Information

Name : NMA0185 (NMA0185)
Accession : YP_002341731.1
Strain : Neisseria meningitidis Z2491
Genome accession: NC_003116
Putative virulence/resistance : Virulence
Product : capsule polysaccharide modification protein
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG3562
EC number : -
Position : 167551 - 168810 bp
Length : 1260 bp
Strand : -
Note : NMA0185, lipB, capsule polysaccharide modification protein, len: 419 aa; almost identical to LIPB_NEIME Q05014 capsule polysaccharide modification protein (419 aa), fasta scores; E(): 0, 99.8% identity in 419 aa overlap, and similar to e.g. KSS5_ECOLI P42

DNA sequence :
ATGAAACAGACCGTCCTCAAAAATAACCTGCAAAACCTGCTTGAAAGCGCAGAAAATATCCTGCTGCTTCAAGGCCCTGT
CGGCGATTTTTTTCTGCGCCTTGCCGACTGGCTGACTGCAAACGGCAAAACCGTACATAAATTCAACTTTAATGCAGGCG
ACGACTATTTTTATCCGCCCACTCAAGCGCATACCGTTGTTTTTAACGACAACTACGATGCCTTTCCTGAGTTTTTGCAA
GAATACATCACTCAACATCACATCCAGGCCGTTGTCTGCTTTGGCGACACACGCCCTTATCACGTCATTGCAAAACGCAT
TGCAAACGAAAACCAAGCCAGTTTCTGGGCGTTTGAAGAAGGCTATTTCCGCCCCTACTACATCACCTTAGAAAAAGACG
GCGTCAACGCATTTTCCCCGTTGCCGCGCCGTGCCGACTTTTTTCTTGAACAATTCCCTAAGCTTGCCCAGCAAGAATAT
AAAGCGCCAACGCCGGTACACGGCGGTTTTACGCCCATGGCAAAAAACGCTATCCGTTACTATATCGAGTTGTTCCGCAA
TCTACGCAAATACCCCGACTACATCCACCACCGCGCACCCAATGCCGGCCATTACCTCAAACCGTGGTCGCTCTCCATCC
TCAAGCGTTTGAACTACTATATTGAAGACATCCAAATCGCCAAACGTGTGGAAGCAGGCAAATACGGCAAGTTTTTTATT
GTTCCCTTGCAGGTATTCAACGACAGCCAAGTCCGTATCCATTGCGACTTTCCCAGCGTCCGCAGCTTCCTGCTCCATGT
TTTGAGTTCATTTGCCGAACACGCGCCTGCCGATACCAACATCATCATCAAGCATCATCCTATGGACCGCGGCTTTATCG
ACTACTGGCGCGACATTAAACGCTTTATCAAAGAACACCCCGAACTCAAAGGCCGTGTGATTTATGTCCATGATGTCCCC
CTGCCCGTTTTCCTGCGCCACGGTCTCGGCATGGTTACCATCAACAGCACCAGCGGCCTGTCCGGACTGATTCACAATAT
GCCAGTTAAGGTTCTCGGCCGTGCCTATTATGATATTCCCGGCATTACTGACCAAAATACCTTGGCAGAATTTTGGAATC
ATCCGACACCGCCTGACAAAGAGCTGTTCCATGCCTACCGAATGTACCACCTCAACGTGACCCAAATTAACGGCAACTTC
TACAGTCAGGTCTTTTTTCCTAACAAAAACACATCCGACTCTTCCACACCAACAACCTAA

Protein sequence :
MKQTVLKNNLQNLLESAENILLLQGPVGDFFLRLADWLTANGKTVHKFNFNAGDDYFYPPTQAHTVVFNDNYDAFPEFLQ
EYITQHHIQAVVCFGDTRPYHVIAKRIANENQASFWAFEEGYFRPYYITLEKDGVNAFSPLPRRADFFLEQFPKLAQQEY
KAPTPVHGGFTPMAKNAIRYYIELFRNLRKYPDYIHHRAPNAGHYLKPWSLSILKRLNYYIEDIQIAKRVEAGKYGKFFI
VPLQVFNDSQVRIHCDFPSVRSFLLHVLSSFAEHAPADTNIIIKHHPMDRGFIDYWRDIKRFIKEHPELKGRVIYVHDVP
LPVFLRHGLGMVTINSTSGLSGLIHNMPVKVLGRAYYDIPGITDQNTLAEFWNHPTPPDKELFHAYRMYHLNVTQINGNF
YSQVFFPNKNTSDSSTPTT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lipB NP_273146.1 capsule polysaccharide modification protein Not tested IHT-A Protein 0.0 99

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
NMA0185 YP_002341731.1 capsule polysaccharide modification protein VFG0260 Protein 0.0 99
NMA0185 YP_002341731.1 capsule polysaccharide modification protein VFG0705 Protein 1e-108 55
NMA0185 YP_002341731.1 capsule polysaccharide modification protein VFG0693 Protein 1e-108 55