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Name : tkt (NMA1669) Accession : YP_002342969.1 Strain : Neisseria meningitidis Z2491 Genome accession: NC_003116 Putative virulence/resistance : Unknown Product : transketolase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0021 EC number : 2.2.1.1 Position : 1590031 - 1592010 bp Length : 1980 bp Strand : + Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo DNA sequence : ATGTCTCAACTGGCAAACGCAATCCGCTTCCTCTCGGCCGATGCCGTTCAAAAAGCCAATTCCGGCCACCCCGGCGCGCC TATGGGTATGGCGGAAATGGCGGAAACATTGTGGACGAAATTCCTCAATCACAATCCCGCCAACCCCAAATTCTACAACC GCGACCGCTTCGTCCTCTCCAACGGCCACGCGTCTATGCTGTTGTACAGCCTGCTGCACCTGACCGGCTACAATCTGAGC ATTGAAGACTTGAAAAACTTCCGCCAACTGCACAGCAAAACCCCCGGCCATCCCGAATACGGCTATACCGACGGCGTGGA AACCACGACCGGCCCGTTGGGGCAAGGGATTGCCAACGCGGTGGGCATGGCATTAGCCGAAAAAATCCTTGCCGCCGAAT TTAATAAAGATGGTTTGAACATCGTCGATCATTACACCTACGTCTTTATGGGCGACGGCTGCCTGATGGAAGGCGTATCG CACGAAGCCTGCTCACTCGCCGGCACTTTGGGCTTGGGCAAACTGATTGTTTTATATGATGACAACAATATTTCCATTGA TGGTAAAGTGGACGGCTGGTTTACCGAAAACATCCCGCAACGCTTTGAAAGCTACGGCTGGCACGTCGTTCCTAACGTAA ACGGTCATGACACCGCCGCCATTCAAGCCGCCATCGAAGCCGCACGTGCCGAAACCGGCAAACCGTCCATCATCTGCTGT AAAACCTTAATCGGCAAAGGCAGTGCCAATAAAGAAGGCAGCCACAAAACCCACGGCGCACCTTTGGGCGCGGACGAAAT CGAAGCCACGCGCAAACATTTGGGCTGGACTTACCCTGCCTTTGAAATCCCGCAAGAAATTTACGATGCGTGGAATGCCA AAGAACAAGGCGCGAAACTGGAAGCCGAATGGAACGAACTCTTCGCGCAATATCAAACCAAATATCCTGCCGAAGCCGCA GAATTTGTGCGCCGTATGGATAAAAAGCTGCCGGACAATTTCGATGAATACGTTCAAGCCGCATTGAAAGAAGTGTGCGC CAAAGCCGAAACCATCGCCACCCGCAAAGCCAGCCAAAACAGCATCGAAATCTTGGCAAAAGAGCTGCCCGAACTGGTGG GCGGCTCTGCCGACCTGACCCCGTCCAACCTGACCGACTGGTCAAACAGCGTTTCCGTTACCCGCGACAAAGGCGGCAAC TACATCCACTACGGCGTGCGCGAGTTCGGTATGGGCGCGATTATGAACGGTTTGGTATTGCACGGCGGCGTAAAACCCTT CGGCGCGACTTTCCTGATGTTCAGCGAATACGAGCGCAACGCCCTGCGTATGGCTGCGTTGATGAAAATCAACCCTGTAT TTGTGTTCACCCACGATTCCATCGGTTTGGGCGAAGACGGCCCGACCCACCAGCCGATTGAGCAAACCGCCACCCTGCGC CTGATTCCGAATATGGACGTATGGCGGCCGTGCGACACCGCCGAATCCTTGGTCGCTTGGGCAGAAGCCGTCAAAGCCGC CGATCACCCGTCCTGCCTGATTTTCAGCCGTCAAAACCTGAAATTCCAAGCGCGCAGCGAGCAACAACTGAACGACATCA AACGCGGCGGCTACGTCATCAGCGAAGCACAAGGCAACGCCCAAGCCGTCATCATTGCCACCGGTTCCGAAGTCGAGCTG GCTTTGGAAGCGCAAAAAGCCCTCGCCGCGCAAAACATCGCCGTGCACGTCGTTTCCATGCCGTCCACCAACGTATTCGA CCGCCAAGACACCGCCTATCAAGCCGCCGTCCTGCCCGAAAGCCTGCCGCGCATCGCCGTAGAAGCCGGACACGCCGACG GCTGGTACAAATACGTCGGACTGAACGGCGCAGTCGTCGGCATCAACCGCTTCGGCGAATCCGCCCCTGCCGATTTACTC TTCAAAGCATTCGGCTTTACCGTGGACAATGTGGTCGATACAGTGAAATCAGTGCTGTAA Protein sequence : MSQLANAIRFLSADAVQKANSGHPGAPMGMAEMAETLWTKFLNHNPANPKFYNRDRFVLSNGHASMLLYSLLHLTGYNLS IEDLKNFRQLHSKTPGHPEYGYTDGVETTTGPLGQGIANAVGMALAEKILAAEFNKDGLNIVDHYTYVFMGDGCLMEGVS HEACSLAGTLGLGKLIVLYDDNNISIDGKVDGWFTENIPQRFESYGWHVVPNVNGHDTAAIQAAIEAARAETGKPSIICC KTLIGKGSANKEGSHKTHGAPLGADEIEATRKHLGWTYPAFEIPQEIYDAWNAKEQGAKLEAEWNELFAQYQTKYPAEAA EFVRRMDKKLPDNFDEYVQAALKEVCAKAETIATRKASQNSIEILAKELPELVGGSADLTPSNLTDWSNSVSVTRDKGGN YIHYGVREFGMGAIMNGLVLHGGVKPFGATFLMFSEYERNALRMAALMKINPVFVFTHDSIGLGEDGPTHQPIEQTATLR LIPNMDVWRPCDTAESLVAWAEAVKAADHPSCLIFSRQNLKFQARSEQQLNDIKRGGYVISEAQGNAQAVIIATGSEVEL ALEAQKALAAQNIAVHVVSMPSTNVFDRQDTAYQAAVLPESLPRIAVEAGHADGWYKYVGLNGAVVGINRFGESAPADLL FKAFGFTVDNVVDTVKSVL |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| tktA | AAO17218.1 | TktA | Not tested | tcd island | Protein | 0.0 | 64 |
| APECO1_2641 | YP_859417.1 | transketolase | Not tested | Not named | Protein | 0.0 | 60 |
