Gene Information

Name : hom (NMA1395)
Accession : YP_002342742.1
Strain : Neisseria meningitidis Z2491
Genome accession: NC_003116
Putative virulence/resistance : Unknown
Product : homoserine dehydrogenase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0460
EC number : 1.1.1.3
Position : 1294192 - 1295499 bp
Length : 1308 bp
Strand : +
Note : catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine

DNA sequence :
ATGAAGCCAGTAAACATCGGTCTTTTAGGTTTGGGTACGGTCGGCGGCGGTACGGCTGCCGTGTTGCGGGACAACGCGGA
GGAAATTTCCCGTCGCTTGGGGCGCGAAATCCGTATTTCTGCCGTGTGCGATTTGAGTGAAGAAAAAGCCCGACAAACCT
GCCCGTCCGCAGCCTTTGTCAAAGATCCGTTCGAACTGGTCGCACGTGAAGACGTCGATGTCGTCGTCGAATTGTTCGGC
GGTACCGGCATTGCCAAAGATGCGGTGTTGAAAGCCATTGAAAACGGCAAACACATCGTTACCGCCAACAAAAAACTGCT
CGCCGAATACGGCAACGAAATCTTCCCGCTGGCGGAAAAACAAAACGTCATCGTCCAATTTGAAGCGGCAGTAGCGGGCG
GTATCCCAATCATCAAAGCCCTGCGCGAAGGTTTGGCGGCAAACAGGATTAAATCCATCGCCGGCATTATTAACGGCACC
AGCAACTTCATCCTCTCCGAAATGCGCGAAAAAGGCAGCGCGTTTGCCGATGTACTGAAAGAAGCGCAGGCATTGGGTTA
TGCCGAAGCCGATCCGACCTTCGACATCGAAGGCAACGATGCGGGCCATAAAATCACCATCATGAGCGCACTGGCATTCG
GCACGCCGATGAACTTTTCCGCCTGCTACCTCGAAGGCATCAGCAAACTCGACAGCCGCGACATCAAATACGCCGAAGAA
CTTGGCTATCGCATCAAACTGTTGGGCATTACCCGCAAAACCGGCAAAGGCATCGAGCTGCGCGTCCACCCTACCCTGAT
TCCCGAAAGCCGCCTCTTGGCAAACGTCAACGGCGTGATGAACGCCGTGCGCGTCAACGCCGATATGGTTGGCGAAACCT
TATATTACGGCGCGGGCGCGGGCGCATTGCCGACCGCTTCCGCCGTGGTTGCCGATATCATCGACATCGCCCGCCTGGTT
GAAGCCGATACCGCCCACCGCGTACCGCATCTGGCGTTCCAACCCGCGCAAGTCCAAGCGCAAACCATCCTGCCTATGGA
CGAAATTACCAGCAGCTACTACCTGCGCGTCCAAGCCAAAGACGAACCGGGCACGCTGGGGCAAATCGCCGCGCTGTTGG
CACAAGAAAACGTGTCCATCGAAGCACTGATTCAAAAAGGCGTGATTGATCAGACCACTGCCGAAATCGTGATTCTGACC
CACAGCACGGTCGAAAAACACATCAAGTCGGCAATCGCAGCCATCGAAGCACTGGATTGCGTGGAAAAACCGATTACCAT
GATCCGCATGGAAAGCCTGCATGACTGA

Protein sequence :
MKPVNIGLLGLGTVGGGTAAVLRDNAEEISRRLGREIRISAVCDLSEEKARQTCPSAAFVKDPFELVAREDVDVVVELFG
GTGIAKDAVLKAIENGKHIVTANKKLLAEYGNEIFPLAEKQNVIVQFEAAVAGGIPIIKALREGLAANRIKSIAGIINGT
SNFILSEMREKGSAFADVLKEAQALGYAEADPTFDIEGNDAGHKITIMSALAFGTPMNFSACYLEGISKLDSRDIKYAEE
LGYRIKLLGITRKTGKGIELRVHPTLIPESRLLANVNGVMNAVRVNADMVGETLYYGAGAGALPTASAVVADIIDIARLV
EADTAHRVPHLAFQPAQVQAQTILPMDEITSSYYLRVQAKDEPGTLGQIAALLAQENVSIEALIQKGVIDQTTAEIVILT
HSTVEKHIKSAIAAIEALDCVEKPITMIRMESLHD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00309 YP_008211635.1 Homoserine dehydrogenase Not tested AbaR26 Protein 4e-93 55
BJAB07104_00305 YP_008207770.1 Homoserine dehydrogenase Not tested AbaR25 Protein 4e-93 55