Gene Information

Name : dnaB (NMA1105)
Accession : YP_002342509.1
Strain : Neisseria meningitidis Z2491
Genome accession: NC_003116
Putative virulence/resistance : Unknown
Product : replicative DNA helicase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0305
EC number : 3.6.1.-
Position : 1053058 - 1054464 bp
Length : 1407 bp
Strand : +
Note : unwinds double stranded DNA

DNA sequence :
ATGAACGATTACACAGCTATGCCGTCTGAAGACCGTGAGGTCGGCGCATTGTCGCTGCCTCCACATTCGATGGAGGCGGA
ACAATCCGTTTTGGGCGGGTTGATGCTGGAAAATCCGGCTTGGGACAGGATTGCCGATGTGGTTTCGGGAGAGGATTTCT
ACCGCCACGAACACCGCCTGATTTTCCGATCCATTGCCAAATTAATCAATGAGAGCCGTCCCGCAGATGTGATTACGGTT
CAGGAAGATTTGCAGCGGAACGAAGAATTGGAAGCGGCAGGCGGATTCGAATATCTGATTACGCTGGCGCAAAACACCCC
GTCTGCCGCCAACATCCGCCGCTACGCCGAAATCGTGCGCGAGCGTTCCATTATGCGCCAACTCGCCGAAGTGGGGACGG
AAATCGCCCGCAGCGCCTACAATCCGCAAGGCAGGGACGCGGGGCAGCTTTTGGACGAGGCGGAAAACAAAGTATTCCAA
ATCGCCGAAAGCACGGCCAAATCCAAGCAGGGCTTTTTGGAGATGCCCGATTTGCTGAAAGAAGTCGTACAGCGCATCGA
TATGCTCTACTCGCGCGACAATCCCGATGAAGTTACCGGTGTGTCGACAGGGTTCATCGACCTCGACAAAAAAACCTCGG
GTCTGCAACCCGGCGACCTGATTATCGTTGCCGGTCGTCCGTCTATGGGTAAGACCGCCTTTTCCATCAATATCGCCGAA
CACGTTGCCGTAGAAGGCAAGCTGCCGGTTGCCGTCTTCTCAATGGAGATGGGCGGGGCGCAACTGGTCATGCGTATGCT
CGGCTCGGTCGGACGCTTGGATCAAAGCGTTTTGAAAACCGGCAGGCTCGAAGACGAACACTGGGGTCGTCTGAACGAAG
CAGTCGTCAAACTCTCCGACGCGCCCGTGTACATCGACGAGACCCCGGGTCTGACTGCGCTCGAACTGCGCGCCCGCGCC
CGTCGTCTCGCCCGTCAATTTAACAATAAGCTGGGATTAATCGTCATCGACTACCTGCAACTGATGGCGGGATCCGGCCG
TTCCGACAACCGTGCTTCGGAGCTTGGCGAAATTTCACGTTCGCTCAAAGCGTTGGCGAAAGAATTGCAAGTCCCCATCA
TCGCCCTGTCGCAATTGAGCCGTACCGTCGAATCGCGTACCGACAAACGCCCGATGATGTCCGACCTCCGCGAATCCGGT
GCTATCGAGCAAGATGCCGACCTGATTATGTTCATGTACCGCGACGAATACTACAACCAAGACTCGCCCATGAAAGGCCT
TGCCGAATGTATCATCGGCAAACACCGCAACGGTCCCGTCGGTAAAATCTTCCTCACATGGACGGGGCAATTCACCAAAT
TCGACAATGCTGCCTATATTCCCGAGGAGGCAAAGATAGAGGATTAA

Protein sequence :
MNDYTAMPSEDREVGALSLPPHSMEAEQSVLGGLMLENPAWDRIADVVSGEDFYRHEHRLIFRSIAKLINESRPADVITV
QEDLQRNEELEAAGGFEYLITLAQNTPSAANIRRYAEIVRERSIMRQLAEVGTEIARSAYNPQGRDAGQLLDEAENKVFQ
IAESTAKSKQGFLEMPDLLKEVVQRIDMLYSRDNPDEVTGVSTGFIDLDKKTSGLQPGDLIIVAGRPSMGKTAFSINIAE
HVAVEGKLPVAVFSMEMGGAQLVMRMLGSVGRLDQSVLKTGRLEDEHWGRLNEAVVKLSDAPVYIDETPGLTALELRARA
RRLARQFNNKLGLIVIDYLQLMAGSGRSDNRASELGEISRSLKALAKELQVPIIALSQLSRTVESRTDKRPMMSDLRESG
AIEQDADLIMFMYRDEYYNQDSPMKGLAECIIGKHRNGPVGKIFLTWTGQFTKFDNAAYIPEEAKIED

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed ABR13456.1 replicative DNA helicase Not tested PAGI-5 Protein 7e-90 49
dnaB CAI36044.1 replicative DNA helicase DnaB Not tested PPHGI-1 Protein 5e-81 46
api2 CAF28476.1 putative DNA binding protein with DNA-dependent ATPase activity Not tested YAPI Protein 1e-81 46
dnaB2 YP_001402701.1 replicative DNA helicase Not tested YAPI Protein 3e-81 46
PMI2640 YP_002152342.1 DNA helicase Not tested Not named Protein 1e-80 45
STY4522 NP_458617.1 DNA helicase Not tested SPI-7 Protein 1e-79 45
t4227 NP_807829.1 DNA helicase Not tested SPI-7 Protein 1e-79 45
dnaB2 YP_001007676.1 putative DNA helicase Not tested YAPI Protein 1e-79 44
dnaB1 YP_005176258.1 replicative DNA helicase Not tested ICEPmu1 Protein 3e-66 41