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Name : lpdA1 (NMB0957) Accession : NP_273995.1 Strain : Neisseria meningitidis MC58 Genome accession: NC_003112 Putative virulence/resistance : Unknown Product : dihydrolipoamide dehydrogenase Function : - COG functional category : C : Energy production and conversion COG ID : COG1249 EC number : 1.8.1.4 Position : 972139 - 973572 bp Length : 1434 bp Strand : + Note : E3 component of 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide DNA sequence : ATGTCTCAATATGATGTAGTAGTGATTGGTGCAGGCCCGGGTGGATACGTTGCCGCCATCCGTGCCGCGCAACTGGGTTT CAAAACCGCTTGCGTCGATGCAGGCGTTAACAAAGCAGGCAATGCCCCTGCATTGGGCGGTACTTGCTTGAACGTAGGCT GTATCCCTTCTAAAGCCCTGTTGCAATCCAGCGAACATTTCCACGCTGCGCAACACGAGTTTGCCGAACACGGTATCACT GTCGGCGACGTAAAATTCGACGCGGCCAAAATGATTGAGCGCAAAGATGCCATCGTGACCAAGCTGACCGGCGGCGTCAA ATTCCTGTTCCAAAAAAATAAAGTAACCAGCCTGTTCGGTACGGCTTCCTTTGCCGGTAAAAATGGCGATGCTTACCAAA TCGAAGTCGATAACAAAGGCGAGAAAACCGTTATCGAAGCCAAACACGTCATCGTAGCCACCGGTTCCGTACCGCGTCCG CTGCCACAAGTCGCTATCGACAATGTGAACGTATTGGACAACGAAGGTGCATTGAACCTGACCGAAGTACCTGCCAAACT CGGCGTGATCGGTTCCGGCGTGATTGGTTTGGAAATGGGTTCCGTATGGAACCGCGTGGGTGCGGAAGTTACCATTCTTG AAGCCGCGCCGACTTTCCTGGCTGCCGCCGACCAACAAATCGCCAAAGAAGCCTTCAAATACTTCACCAAAGAGCAAGGT CTGAGCATCGAATTGGGCGTGAAAATCGGCGACATCAAGTCTGAAGGCAAAGGTGTTTCCGTTGCTTACGAAACTGCTGC TGGCGAAGCCAAAACCGAAGTATTCGACAAACTGATCGTTGCCATCGGCCGTATTCCAAACACCAAAGGCCTGAACGCGG AAGCCGTAGGCTTGGAAAAAGACGAGCGCGGCTTTATCAAAGTAGATGGCGAATGCCGTACCAACCTGCCTAACGTATGG GCAATCGGCGACGTGGTTCGCGGCCCGATGTTGGCACACAAAGCCAGCGACGAAGGCGTTGCCGTTGCCGAACGCATTGC CGGTCAAAAACCGCATATCGACTTCAACAACGTACCGTTCGTGATTTACACCGATCCTGAAATCGCTTGGGTGGGTAAAA CCGAAGAGCAGCTCAAAGCCGAAGGCGTGGAGTACAAAAAAGGTACTTCAGGTTTTGGTGCGAATGGTCGCGCATTGGCA ATGGGCAAAGCCAAAGGTACGGTTAAAGTGTTGGCAGATGCCAAAACCGACCGCATCTTGGGCGTACACATGATTGGTCC GGTTGTCAGCGAATTGGTTACCGAAGGCGTGACTGCGCTCGAATTCTTCGCCAGCAGCGAAGACATCGCCCGCATTATCC ATGCCCACCCAACCTTGTCCGAAGTGGTTCACGAAGCTGCATTGGCGGCCGACAAACGCGCTTTGCACGGTTGA Protein sequence : MSQYDVVVIGAGPGGYVAAIRAAQLGFKTACVDAGVNKAGNAPALGGTCLNVGCIPSKALLQSSEHFHAAQHEFAEHGIT VGDVKFDAAKMIERKDAIVTKLTGGVKFLFQKNKVTSLFGTASFAGKNGDAYQIEVDNKGEKTVIEAKHVIVATGSVPRP LPQVAIDNVNVLDNEGALNLTEVPAKLGVIGSGVIGLEMGSVWNRVGAEVTILEAAPTFLAAADQQIAKEAFKYFTKEQG LSIELGVKIGDIKSEGKGVSVAYETAAGEAKTEVFDKLIVAIGRIPNTKGLNAEAVGLEKDERGFIKVDGECRTNLPNVW AIGDVVRGPMLAHKASDEGVAVAERIAGQKPHIDFNNVPFVIYTDPEIAWVGKTEEQLKAEGVEYKKGTSGFGANGRALA MGKAKGTVKVLADAKTDRILGVHMIGPVVSELVTEGVTALEFFASSEDIARIIHAHPTLSEVVHEAALAADKRALHG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SE0077 | NP_763632.1 | dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 | Not tested | SCCpbp4 | Protein | 4e-65 | 42 |
