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Name : hsdM (NMB0829) Accession : NP_273871.1 Strain : Neisseria meningitidis MC58 Genome accession: NC_003112 Putative virulence/resistance : Unknown Product : type I restriction enzyme EcoR124II M protein Function : - COG functional category : V : Defense mechanisms COG ID : COG0286 EC number : 2.1.1.72 Position : 852367 - 853911 bp Length : 1545 bp Strand : + Note : identified by similarity to GP:450688; match to protein family HMM PF02384; match to protein family HMM PF02506; match to protein family HMM TIGR00497 DNA sequence : ATGATGACCGAAATGCAACAACGCGCCCAACTGCACCGCCAAATTTGGAAAATTGCCGACGAAGTACGCGGCGCGGTGGA TGGCTGGGACTTTAAACAATACGTTCTCGGCACACTTTTCTACCGCTTTATCAGCGAAAACTTCACCGACTATATGCAGG CAGGCGACAGCAGTATTGATTACGCCGCTATGCCGGACAGCATCATCACGCCCGAAATCAAAGACGATGCCGTCAAAGTT AAAGGCTATTTCATCTACCCCGGCCAGCTTTTTTGCAATATTGCCGCCGAAGCCCATCAAAACGAAGAGCTCAACACCAA GCTGAAAGAAATTTTTACCGCGATTGAAAGCTCCGCCTCCGGCTATCCGTCCGAACAGGACATCAAAGGCCTGTTTGACG ACTTCGACACCACCAGCAGCCGGCTCGGCAGCACTGTTGCCGACAAGAACAAACGCCTTGCCGCCGTCCTCAAAGGCGTG GCGGAACTCGATTTCGGCAATTTTGAAAACCACCACATCGACCTTTTCGGCGATGCCTACGAATACCTGATTTCCAACTA CGCTGCCAACGCAGGCAAATCCGGCGGCGAATTTTTCACCCCGCAAAGCGTATCCAAGCTGATTGCGCGGCTGGCGGTGC ACGGACAGGAGAAAGTCAACAAAATCTACGACCCAGCTTGCGGCTCGGGCAGTCTGCTCTTGCAGGCGAAAAAACAGTTT GACGAGCACATCATCGAAGAAGGCTTCTTCGGGCAGGAAATCAACCACACCACCTACAACCTCGCCCGCATGAACATGTT CCTGCACAACGTCAATTACAACCAATTCCACATCGAATTGGGCGACACACTGACCAACCCAAAGCTCAAAGACAGCAAAC CCTTTGATGCCATCGTTTCCAATCCGCCTTATTCCATCAACTGGATAGGCAGCGACGACCCCACCTTAATCAACGACGAC CGCTTTGCCCCCGCAGGCGTACTTGCCCCGAAATCCAAAGCCGATTTTGCCTTCATCCTGCACGCACTGAACTACCTTTC CGGCAGAGGCCGCGCCGCCATCGTCTCATTCCCCGGCATTTTCTATCGCGGCGGCGCAGAACAGAAAATCCGCCAATATC TGGTGGAGGGCAACTACGTGGAAACCGTGATTGCCCTTGCGCCCAATCTCTTTTACGGCACCGGCATCGCCGTCAATATC CTGGTTTTGTCCAAACACAAAGACAATACCGACATCCAATTCATCGACGCAAGCGGCTTCTTTAAAAAAGAAACCAACAA CAACGTCTTAATCGAAGAACACATTGCTGAAATCGTCAAACTCTTCGCCGATAAAGCCGATGTGCCGCATATCGCCCAAA ACGCTGCCCAGCAAACCGTCAAAGACAACGGCTACAACCTCGCCGTCAGCAGCTATGTCGAAGCCGAAGACACACGCGAA ATTATCGACATCAAACAGCTCAACGCCGAAATCGGCGAAACCGTCGCCAAAATCGAACGGCTGCGGCGTGAAATTGACGA AGTGATTGCAGAGATTGAAGCATGA Protein sequence : MMTEMQQRAQLHRQIWKIADEVRGAVDGWDFKQYVLGTLFYRFISENFTDYMQAGDSSIDYAAMPDSIITPEIKDDAVKV KGYFIYPGQLFCNIAAEAHQNEELNTKLKEIFTAIESSASGYPSEQDIKGLFDDFDTTSSRLGSTVADKNKRLAAVLKGV AELDFGNFENHHIDLFGDAYEYLISNYAANAGKSGGEFFTPQSVSKLIARLAVHGQEKVNKIYDPACGSGSLLLQAKKQF DEHIIEEGFFGQEINHTTYNLARMNMFLHNVNYNQFHIELGDTLTNPKLKDSKPFDAIVSNPPYSINWIGSDDPTLINDD RFAPAGVLAPKSKADFAFILHALNYLSGRGRAAIVSFPGIFYRGGAEQKIRQYLVEGNYVETVIALAPNLFYGTGIAVNI LVLSKHKDNTDIQFIDASGFFKKETNNNVLIEEHIAEIVKLFADKADVPHIAQNAAQQTVKDNGYNLAVSSYVEAEDTRE IIDIKQLNAEIGETVAKIERLRREIDEVIAEIEA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SAS1732 | YP_043848.1 | type I restriction enzyme modification protein | Not tested | vSa¥â | Protein | 4e-93 | 41 |
| hsdM | NP_646568.1 | hypothetical protein | Not tested | vSa¥â | Protein | 4e-93 | 41 |
| SAV1808 | NP_372332.1 | type I restriction enzyme EcoR124II M protein | Not tested | vSa¥â | Protein | 4e-93 | 41 |
| SA1626 | NP_374915.1 | hypothetical protein | Not tested | vSa¥â | Protein | 4e-93 | 41 |
| SAMSHR1132_03780 | YP_005324900.1 | putative type I restriction enzyme modification protein | Not tested | vSa¥á | Protein | 2e-92 | 41 |
| hsdM | NP_645209.1 | type I site-specific deoxyribonuclease LldI chain hsdM | Not tested | vSa¥á | Protein | 8e-93 | 41 |
| SAS0394 | YP_042520.1 | restriction enzyme modification protein | Not tested | vSa¥á | Protein | 7e-93 | 41 |
| SAMSHR1132_16570 | YP_005326167.1 | restriction-modification system, M subunit | Not tested | vSa¥â | Protein | 3e-92 | 41 |
