Gene Information

Name : purA (NMB0815)
Accession : NP_273857.1
Strain : Neisseria meningitidis MC58
Genome accession: NC_003112
Putative virulence/resistance : Unknown
Product : adenylosuccinate synthetase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0104
EC number : 6.3.4.4
Position : 840201 - 841505 bp
Length : 1305 bp
Strand : +
Note : catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis

DNA sequence :
ATGGCTATGGCTAAAAATGTTGTAGTAATCGGCGCACAGTGGGGCGACGAGGGTAAAGGTAAAATCGTTGACTGGCTGGC
GGAAGAAGCCGGCGGCGTGGTGCGCTTCCAAGGCGGCCACAATGCGGGCCATACCTTGGTTGTCGGCGGCAAAAAAACCA
TTTTGCGCCTGATTCCGAGCGGCATCCTGCATGAAAGTTTGGACTGCTTCATCGGTTCGGGCGTTGTCGTCTCCCCCGAA
GCCCTGTTGGGCGAAATCGACGAGTTGAACGCGGCAGGCGTGAAAAACGTCGAAGGCCGTCTGAAAATCGCGCCGACCTG
CCCGCTGATCCTGCCTTACCACATCGCGCTCGACCAAGCCCGCGAAGCATCGCGCGGCAAAGGCAAAATCGGCACGACCG
GCCGCGGCATCGGCCCTGCCTACGAAGACAAAGTGGCACGCCGCGCCATTCGCGCCGCCGATTTGCTGCATCCTGAAAAA
CTGCGTGAAAAACTGGATGCCGTCCTTGCCTATTACAATGTCCAACTGCAACATCTGCACAATGCCGAGCCGGTTAAAGC
GGAAGACGTGATGGCGGTTATCGAAAAAGTCGCGCCGCGCATTGCGCCGATGATTACCGACGTGTCCCGCGTGTTGAACG
AGAAAAACAAAAACGGCGAAAAACTGCTGTTTGAAGGCGCGCAAGGTGCGTTGTTGGACATCGACTACGGCACTTATCCC
TTCGTTACCTCGTCCAACTGTCTGGCGGGCGCAGCTTCGGCAGGCGCGGGCGTAGGTCCTCAAATGCTGGATTATGTTTT
GGGCATCGTCAAAGCCTATACCACGCGCGTCGGTTCGGGCCCGTTCCCGACCGAATTGTTCGACGAAGTAGGCGTAGGTT
TGGCAGAACGCGGACACGAATTCGGTTCGGTAACCGGACGCGCACGCCGCTGCGGCTGGTTTGATGCCGCCGCCCTGAAA
CGCTCCATCCAAATCAACGGCATTTCCGGTATGTGTATTACTAAACTCGATGTAATGGACGGCGTTGAAACCATCAATAT
CTGCGTCGGCTATGAATTGCCCGACGGCGGCAAAACCGACATCCTGCCTTGCGGTTCCGATGCGGTGGAAACCTGCAAGC
CGATTTACGAAACCATGCCCGGCTGGCGCGAATCCACTTTCGGCGTGAAGGACTACGGCGCATTGCCCGAAAACGCCAAA
GCATATTTGAAACGGATTGAAGAAGTCTGCGGCGCGCCGGTCGCCATCGTCTCCACCGGCCCCGACCGAGAAGAAACGAT
TGTGCTGCATCATCCGTTCGCATAA

Protein sequence :
MAMAKNVVVIGAQWGDEGKGKIVDWLAEEAGGVVRFQGGHNAGHTLVVGGKKTILRLIPSGILHESLDCFIGSGVVVSPE
ALLGEIDELNAAGVKNVEGRLKIAPTCPLILPYHIALDQAREASRGKGKIGTTGRGIGPAYEDKVARRAIRAADLLHPEK
LREKLDAVLAYYNVQLQHLHNAEPVKAEDVMAVIEKVAPRIAPMITDVSRVLNEKNKNGEKLLFEGAQGALLDIDYGTYP
FVTSSNCLAGAASAGAGVGPQMLDYVLGIVKAYTTRVGSGPFPTELFDEVGVGLAERGHEFGSVTGRARRCGWFDAAALK
RSIQINGISGMCITKLDVMDGVETINICVGYELPDGGKTDILPCGSDAVETCKPIYETMPGWRESTFGVKDYGALPENAK
AYLKRIEEVCGAPVAIVSTGPDREETIVLHHPFA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
purA YP_281500.1 adenylosuccinate synthetase Not tested Not named Protein 1e-87 48