Gene Information

Name : metB (NMB0802)
Accession : NP_273844.1
Strain : Neisseria meningitidis MC58
Genome accession: NC_003112
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 828295 - 829452 bp
Length : 1158 bp
Strand : -
Note : identified by similarity to EGAD:109991; match to protein family HMM PF01053

DNA sequence :
ATGAAATTCGCCACGAAAGCCATTCATTCCAGCTACGATTGCGACGAACACAACCGCGCGCTGATGCCGCCGATTTATCA
AAACAGTATGTTTGCGTTGCACGAGATTGGCGAAAATGTGCCTTACCGTTATTCGCGCCTGAGCAACCCGACCCGTCAGA
TTTTAGAAGACACCGTTGCCGATTTGGAACACGGTGCGGCAGGTTTTGCGTTTTCCAGCGGTATGGCGGGAATTGATGCC
GTATGGCGCACTTTCCTGCGCCCGGGCGATACCATTGTCGCCGTCGCCGATATTTACGGCGGCGCTTATGATTTATTGGT
CGATGTTTATCAAAAATGGGGGGTGAACGTTGTTTTTGCCGATTTAGGCAATCCGGATAATTTGGACGAACTGCTTAAAG
CGCACAAGGTCAAACTGGTTTGGCTGGAAACGCCGTCCAATCCACTTTTACGCTTGGTAGACATCAAAGTCCTTGCCGCA
AAAGCCAAAGCAGCCGGTGCGCTGGTCGGTATCGACAACACTTTTGCCACGCCGTATCTGCAACAGCCGTTGGATATGGG
TTGCGATTTTGTATTCCATTCCGCTACCAAATATTTGTGCGGCCATTCCGACGTGTTGATGGGCATCGTCGTTGCCAAAA
CCAAAGAACTGGCGCAGCCTTTGCACGATATGATGGTGCATACCGGCGCGGTTGCCGGCCCGCTGGACTGCTGGCTGGTG
TTGCGCGGCATCAAAACACTGGCTCTGCGCATGAACGCCCATTGCCAAAACGCACTCGAAATCGCGCGCCGTTTGGAAGC
CCATCCTGCCATTGAAAAAGTGTTCCATCCCGGCCTGCCGTCTCACGAACATTACGAACTGGCGAAAACACAAATGCCCA
AAGGCATCGGCGGCGTGGTTACGGTTTATCTCAAAAACGACACGCGTGAAGCGGCAAACAGCGTGATTAAAAACATGAAA
CTGGTCAAAATGGCTTCCAGCCTCGGCGGTGTGGAAAGTTTGGTCAACCATTGCTATTCCCAGTCCCACAGCGGCGTACC
GCATGATGTGAAAATGGAAATGGGCATCAAAGTCGGTCTGCTGCGTTTCTCCATCGGCATCGAAGACGCGGACGATATTT
GGAACGATATTTCCGCCGCACTCGATACAACTTTGTAA

Protein sequence :
MKFATKAIHSSYDCDEHNRALMPPIYQNSMFALHEIGENVPYRYSRLSNPTRQILEDTVADLEHGAAGFAFSSGMAGIDA
VWRTFLRPGDTIVAVADIYGGAYDLLVDVYQKWGVNVVFADLGNPDNLDELLKAHKVKLVWLETPSNPLLRLVDIKVLAA
KAKAAGALVGIDNTFATPYLQQPLDMGCDFVFHSATKYLCGHSDVLMGIVVAKTKELAQPLHDMMVHTGAVAGPLDCWLV
LRGIKTLALRMNAHCQNALEIARRLEAHPAIEKVFHPGLPSHEHYELAKTQMPKGIGGVVTVYLKNDTREAANSVIKNMK
LVKMASSLGGVESLVNHCYSQSHSGVPHDVKMEMGIKVGLLRFSIGIEDADDIWNDISAALDTTL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-61 44
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 9e-63 44