Gene Information

Name : ctrB (NMB0072)
Accession : NP_273136.1
Strain : Neisseria meningitidis MC58
Genome accession: NC_003112
Putative virulence/resistance : Virulence
Product : capsule polysaccharide export inner-membrane protein
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG3524
EC number : -
Position : 81572 - 82735 bp
Length : 1164 bp
Strand : +
Note : identified by similarity to EGAD:20633; match to protein family HMM PF02706; match to protein family HMM TIGR01010

DNA sequence :
ATGTCTGAGCAACTTCCTGTGGCAGTTGCCACTGAAACCAAAGCCGAGCGTAAAAAGCCGAAAAAGAAAAGTTGGATTAA
AAAGCTAAGCCCTTTATTTTGGGTAACGGTGATTATCCCTACGGTAATTTCGTTGGTGTATTTCGGCTTCTTCGCTTCCG
ATCGTTTTACGTCGCAATCGAGCTTTGTGGTGCGCTCGCCTAAAAGCCAATCTTCTCTCAATGGCCTGGGTGCCATTTTG
CAGGGCACAGGTTTTGCCCGTGCGCAAGATGATATTTACACGGTTGGGGAGTATATGCGTTCGCGCTCGTCTTTGGATGA
ACTGCGTAAAATCTTGCCGGTGCGTGAGTTTTATGAAACCAAAGGTGATGCGTTCAGCCGCTTTAATGGGTTTGGGTTCC
GTGGCGAGGAAGAGGCTTTTTATCAATACTATAAAAATCAGGTGATGATCAATTTTGATACGGTTTCGGGTATTTCCACG
TTGAATGTAACTTCCTTTGATGCGCTGGAATCTAAGAAAATCAATGAGGCTTTGTTAAAACAAGGTGAAGCATTGATTAA
CCAGTTGAACGATCGTGCACGTGCTGATACGGTGCGCTATGCGGAAGAAGTAGTGAAAACGGCGGCAGAGCGGGTAAAGG
AAGCCTCTCAGAATCTGACGGATTACCGGATTGCCAATGGCGTTTTTGATTTGAAAGCGCAATCGGAAGTGCAAATGGGG
TTGGTTTCCAAGCTGCAAGATGAATTGATTGTGATTCAAACCCAGCTGGATCAGGTGAAAGCAGTCACTCCGGAGAATCC
GCAGATTCCGGGTTTGCAGGCGCGTGAGCAGAGCTTGCGTAAAGAAATTGACCAACAGTTACGTGCCATTTCGGGCGGTG
GGCATTCTTCGTTGTCTAATCAGGCTGCCGAATATCAGCGTGTGTATTTGGAAAACCAGTTGGCAGAGCAGCAGTTGGCA
GCCGCCATGACTTCTTTGGAAAGTGCCAAGGTTGAAGCAGACCGTCAGCAGCTTTATTTGGAAGTGATCTCGCAACCGAG
CCTGCCGGATTTGGCACATGAGCCTAAACGGTTATACAACATTGTTGCCACTCTGATTATCGGCTTGATGGTTTATGGTA
TTTTGAGCCTGTTGACTGCCAGCATTCGTGAGCATAAAAACTGA

Protein sequence :
MSEQLPVAVATETKAERKKPKKKSWIKKLSPLFWVTVIIPTVISLVYFGFFASDRFTSQSSFVVRSPKSQSSLNGLGAIL
QGTGFARAQDDIYTVGEYMRSRSSLDELRKILPVREFYETKGDAFSRFNGFGFRGEEEAFYQYYKNQVMINFDTVSGIST
LNVTSFDALESKKINEALLKQGEALINQLNDRARADTVRYAEEVVKTAAERVKEASQNLTDYRIANGVFDLKAQSEVQMG
LVSKLQDELIVIQTQLDQVKAVTPENPQIPGLQAREQSLRKEIDQQLRAISGGGHSSLSNQAAEYQRVYLENQLAEQQLA
AAMTSLESAKVEADRQQLYLEVISQPSLPDLAHEPKRLYNIVATLIIGLMVYGILSLLTASIREHKN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ctrB NP_273136.1 capsule polysaccharide export inner-membrane protein Not tested IHT-A Protein 5e-158 100

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ctrB NP_273136.1 capsule polysaccharide export inner-membrane protein VFG0256 Protein 2e-158 100
ctrB NP_273136.1 capsule polysaccharide export inner-membrane protein VFG0686 Protein 5e-101 62
ctrB NP_273136.1 capsule polysaccharide export inner-membrane protein VFG0698 Protein 5e-101 62
ctrB NP_273136.1 capsule polysaccharide export inner-membrane protein VFG2565 Protein 1e-63 43