Gene Information

Name : ctrA (NMB0071)
Accession : NP_273135.1
Strain : Neisseria meningitidis MC58
Genome accession: NC_003112
Putative virulence/resistance : Virulence
Product : capsule polysaccharide export outer membrane protein
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1596
EC number : -
Position : 80382 - 81557 bp
Length : 1176 bp
Strand : +
Note : identified by similarity to EGAD:23947; match to protein family HMM PF02563

DNA sequence :
GTGTTTAAAGTGAAATTTTATATTCGTCACGCAGTATTATTATTGTGTGGAAGTTTAATTGTAGGATGCTCTGCGATTCC
TTCATCAGGCCCCAGCGCAAAAAAAATTGTCTCTTTAGGGCAACAATCTGAAGTTCAAATTCCTGAAGTGGAGCTGATTG
ATGTGAATCATACGGTTGCTCAGTTATTATATAAGGCTCAGATAAATCAGTCATTCACTCAGTTTGGCGATGGTTATGCT
TCGGCTGGTACGCTAAATATTGGTGATGTATTGGATATTATGATTTGGGAAGCGCCGCCGGCAGTATTGTTTGGTGGTGG
CCTTTCTTCGATGGGCTCGGGTAGTGCGCATCAAACTAAGTTGCCAGAGCAGTTGGTCACGGCACGTGGTACGGTTTCTG
TGCCGTTTGTTGGCGATATTTCGGTGGTCGGTAAAACGCCTGGTCAGGTTCAGGAAATTATTAAAGGCCGCCTGAAAAAA
ATGGCCAATCAGCCACAAGTGATGGTGCGTTTGGTGCAGAATAATGCGGCGAATGTGTCGGTGATTCGTGCTGGGAATAG
TGTGCGTATGCCGCTGACGGCAGCCGGTGAGCGTGTGTTGGATGCGGTGGCTGCGGTAGGTGGTTCAACGGCAAATGTGC
AGGATACGAATGTGCAGCTGACACGTGGCAATGTAGTACGAACTGTTGCCTTGGAAGATTTAGTTGCAAATCCGCGACAA
AATATTTTGCTGCGTCGCGGTGATGTGGTTACCATGATTACCAATCCCTATACCTTTACGTCTATGGGTGCGGTGGGGAG
AACACAAGAAATCGGTTTTTCAGCCAGAGGCTTATCGCTTTCTGAAGCCATTGGCCGTATGGGCGGTTTGCAAGATCGCC
GTTCTGATGCGCGTGGTGTGTTTGTGTTCCGCTATACGCCATTGGTGGAATTGCCGGCAGAACGTCAGGATAAATGGATT
GCTCAAGGTTATGGCAGTGAGGCAGAGATTCCAACGGTATATCGTGTGAATATGGCTGATGCGCATTCGCTATTTTCTAT
GCAGCGCTTTCCTGTGAAGAATAAAGATGTATTGTATGTGTCGAATGCGCCGTTGGCTGAAGTGCAGAAATTTTTGTCGT
TTGTGTTCTCGCCGGTTACCAGTGGCGCGAACAGTATTAATAATTTAACTAATTAA

Protein sequence :
MFKVKFYIRHAVLLLCGSLIVGCSAIPSSGPSAKKIVSLGQQSEVQIPEVELIDVNHTVAQLLYKAQINQSFTQFGDGYA
SAGTLNIGDVLDIMIWEAPPAVLFGGGLSSMGSGSAHQTKLPEQLVTARGTVSVPFVGDISVVGKTPGQVQEIIKGRLKK
MANQPQVMVRLVQNNAANVSVIRAGNSVRMPLTAAGERVLDAVAAVGGSTANVQDTNVQLTRGNVVRTVALEDLVANPRQ
NILLRRGDVVTMITNPYTFTSMGAVGRTQEIGFSARGLSLSEAIGRMGGLQDRRSDARGVFVFRYTPLVELPAERQDKWI
AQGYGSEAEIPTVYRVNMADAHSLFSMQRFPVKNKDVLYVSNAPLAEVQKFLSFVFSPVTSGANSINNLTN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ctrA NP_273135.1 capsule polysaccharide export outer membrane protein Not tested IHT-A Protein 4e-177 100

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ctrA NP_273135.1 capsule polysaccharide export outer membrane protein VFG0255 Protein 2e-177 100
ctrA NP_273135.1 capsule polysaccharide export outer membrane protein VFG0699 Protein 2e-100 53
ctrA NP_273135.1 capsule polysaccharide export outer membrane protein VFG0687 Protein 2e-100 53
ctrA NP_273135.1 capsule polysaccharide export outer membrane protein VFG2566 Protein 6e-72 42