Gene Information

Name : siaC (NMB0068)
Accession : NP_273132.1
Strain : Neisseria meningitidis MC58
Genome accession: NC_003112
Putative virulence/resistance : Virulence
Product : polysialic acid capsule biosynthesis protein SiaC
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG2089
EC number : -
Position : 77374 - 78423 bp
Length : 1050 bp
Strand : -
Note : identified by similarity to EGAD:19609; match to protein family HMM PF01354; match to protein family HMM PF03102

DNA sequence : 
ATGCAAAACAACAACGAATTTAAAATTGGTAATCGTTCAGTAGGTTACAACCACGAACCATTGATTATCTGTGAAATCGG
CATCAATCATGAAGGCTCTTTAAAAACAGCTTTTGAAATGGTTGATGCTGCCTATAATGCAGGCGCTGAAGTTGTTAAAC
ATCAAACACACATCGTTGAAGACGAAATGTCTGATGAGGCCAAACAAGTCATTCCAGGCAATGCAGATGTCTCTATTTAT
GAAATTATGGAACGTTGCGCCCTGAATGAAGAAGATGAGATTAAATTAAAAGAATACGTAGAGAGTAAGGGTATGATTTT
TATCAGTACTCCTTTCTCTCGTGCAGCTGCTTTACGATTACAACGTATGGATATTCCAGCATATAAAATCGGCTCTGGCG
AATGTAATAACTACCCATTAATTAAACTGGTGGCCTCTTTTGGTAAGCCTATTATTCTCTCTACCGGCATGAATTCTATT
GAAAGCATCAAAAAGTCGGTAGAAATTATTCGAGAAGCAGGGGTACCTTATGCTTTGCTTCACTGTACCAACATCTACCC
AACCCCTTACGAAGATGTTCGATTGGGTGGTATGAACGATTTATCTGAAGCCTTTCCAGACGCAATCATTGGCCTGTCTG
ACCATACCTTAGATAACTATGCTTGCTTAGGAGCAGTAGCTTTAGGCGGTTCGATTTTAGAGCGTCACTTTACTGACCGC
ATGGATCGCCCAGGTCCGGATATTGTATGCTCTATGAATCCGGATACTTTTAAAGAGCTCAAGCAAGGCGCTCATGCTTT
AAAATTGGCACGCGGCGGCAAAAAAGACACGATTATCGCGGGAGAAAAGCCAACTAAAGATTTCGCCTTTGCATCTGTCG
TAGCAGATAAAGACATTAAAAAAGGAGAACTGTTGTCCGGAGATAACCTATGGGTTAAACGCCCAGGCAATGGAGACTTC
AGCGTCAACGAATATGAAACATTATTTGGTAAGGTCGCTGCTTGCAATATTCGCAAAGGTGCTCAAATCAAAAAAACTGA
TATTGAATAA

Protein sequence : 
MQNNNEFKIGNRSVGYNHEPLIICEIGINHEGSLKTAFEMVDAAYNAGAEVVKHQTHIVEDEMSDEAKQVIPGNADVSIY
EIMERCALNEEDEIKLKEYVESKGMIFISTPFSRAAALRLQRMDIPAYKIGSGECNNYPLIKLVASFGKPIILSTGMNSI
ESIKKSVEIIREAGVPYALLHCTNIYPTPYEDVRLGGMNDLSEAFPDAIIGLSDHTLDNYACLGAVALGGSILERHFTDR
MDRPGPDIVCSMNPDTFKELKQGAHALKLARGGKKDTIIAGEKPTKDFAFASVVADKDIKKGELLSGDNLWVKRPGNGDF
SVNEYETLFGKVAACNIRKGAQIKKTDIE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
siaC NP_273132.1 polysialic acid capsule biosynthesis protein SiaC Not tested IHT-A Protein 7e-158 100

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
siaC NP_273132.1 polysialic acid capsule biosynthesis protein SiaC VFG0252 Protein 3e-158 100