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Name : ermC (NMB0066) Accession : NP_273130.1 Strain : Neisseria meningitidis MC58 Genome accession: NC_003112 Putative virulence/resistance : Resistance Product : rRNA adenine N-6-methyltransferase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0030 EC number : 2.1.1.48 Position : 75694 - 76428 bp Length : 735 bp Strand : + Note : identified by similarity to EGAD:8424; match to protein family HMM PF00398 DNA sequence : ATGAACGAGAAAAATATAAAACACAGTCAAAACTTTATTACTTCAAAACATAATATAGATAAAATAATGACAAATATAAG ATTAAATGAACATGATAATATCTTTGAAATCGGCTCAGGAAAAGGGCATTTTACCCTTGAATTAGTACAGAGGTGTAATT TCGTAACTGCCATTGAAATAGACCATAAATTATGCAAAACTACAGAAAATAAACTTGTTGATCACGATAATTTCCAAGTT TTAAACAAGGATATATTGCAGTTTAAATTTCCTAAAAACCAATCCTATAAAATATTTGGTAATATACCTTATAACATAAG TACGGATATAATACGCAAAATTGTTTTTGATAGTATAGCTGATGAGATTTATTTAATCGTGGAATACGGGTTTGCTAAAA GATTATTAAATACAAAACGCTCATTGGCATTATTTTTAATGGCAGAAGTTGATATTTCTATATTAAGTATGGTTCCAAGA GAATATTTTCATCCTAAACCTAAAGTGAATAGCTCACTTATCAGATTAAATAGAAAAAAATCAAGAATATCACACAAAGA TAAACAGAAGTATAATTATTTCGTTATGAAATGGGTTAACAAAGAATACAAGAAAATATTTACAAAAAATCAATTTAACA ATTCCTTAAAACATGCAGGAATTGACGATTTAAACAATATTAGCTTTGAACAATTCTTATCTCTTTTCAATAGCTATAAA TTATTTAATAAGTAA Protein sequence : MNEKNIKHSQNFITSKHNIDKIMTNIRLNEHDNIFEIGSGKGHFTLELVQRCNFVTAIEIDHKLCKTTENKLVDHDNFQV LNKDILQFKFPKNQSYKIFGNIPYNISTDIIRKIVFDSIADEIYLIVEYGFAKRLLNTKRSLALFLMAEVDISILSMVPR EYFHPKPKVNSSLIRLNRKKSRISHKDKQKYNYFVMKWVNKEYKKIFTKNQFNNSLKHAGIDDLNNISFEQFLSLFNSYK LFNK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| ermC | NP_273130.1 | rRNA adenine N-6-methyltransferase | Not tested | IHT-A | Protein | 1e-110 | 100 |
| unnamed | BAB47663.1 | rRNA adenine N-6-methyltransferase | Not tested | Type-III SCCmec | Protein | 2e-62 | 57 |
| unnamed | BAC53825.1 | rRNA adenine N-6-methyltransferase | Not tested | SRImec-III and SCCmec-III region | Protein | 2e-62 | 57 |
| ermA | BAC57474.1 | rRNA methylase | Not tested | Type-IIIinv SCCmec | Protein | 7e-63 | 57 |
| ermA | BAA82205.1 | rRNA adenine N-6-methyltransferase | Not tested | Type-II SCCmec | Protein | 7e-63 | 57 |
| ermA1 | YP_039522.1 | rRNA adenine N-6-methyltransferase 1 | Not tested | Type-II SCCmec | Protein | 1e-62 | 57 |
| ermA | NP_370576.1 | rRNA methylase | Not tested | Type-II SCCmec | Protein | 1e-62 | 57 |
| ermA | NP_373288.1 | rRNA methylase | Not tested | Type-II SCCmec | Protein | 1e-62 | 57 |
| ermA-3 | YP_190052.1 | rRNA adenine N-6-methyltransferase | Not tested | Type-II SCCmec | Protein | 1e-62 | 57 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| ermC | NP_273130.1 | rRNA adenine N-6-methyltransferase | NC_010686.6295746.p0 | Protein | 5e-111 | 100 |
| ermC | NP_273130.1 | rRNA adenine N-6-methyltransferase | NC_010685.6295744.p0 | Protein | 5e-111 | 100 |
| ermC | NP_273130.1 | rRNA adenine N-6-methyltransferase | NC_007209.3523503.p0 | Protein | 7e-111 | 99 |
| ermC | NP_273130.1 | rRNA adenine N-6-methyltransferase | NC_007792.3912746.p0 | Protein | 3e-110 | 99 |
| ermC | NP_273130.1 | rRNA adenine N-6-methyltransferase | V01278.gene.p01 | Protein | 2e-109 | 98 |
| ermC | NP_273130.1 | rRNA adenine N-6-methyltransferase | M64090.gene.p01 | Protein | 4e-88 | 78 |
| ermC | NP_273130.1 | rRNA adenine N-6-methyltransferase | AJ313523.1.orf0.gene | Protein | 1e-81 | 75 |
| ermC | NP_273130.1 | rRNA adenine N-6-methyltransferase | M15332.gene.p01 | Protein | 5e-82 | 72 |
| ermC | NP_273130.1 | rRNA adenine N-6-methyltransferase | NC_002745.1124852.p0 | Protein | 5e-63 | 57 |
| ermC | NP_273130.1 | rRNA adenine N-6-methyltransferase | NC_009782.5559229.p0 | Protein | 5e-63 | 57 |
| ermC | NP_273130.1 | rRNA adenine N-6-methyltransferase | NC_002758.1120012.p0 | Protein | 5e-63 | 57 |
| ermC | NP_273130.1 | rRNA adenine N-6-methyltransferase | NC_002952.2859614.p0 | Protein | 5e-63 | 57 |
| ermC | NP_273130.1 | rRNA adenine N-6-methyltransferase | NC_002745.1122822.p0 | Protein | 5e-63 | 57 |
| ermC | NP_273130.1 | rRNA adenine N-6-methyltransferase | NC_002745.1124324.p0 | Protein | 5e-63 | 57 |
| ermC | NP_273130.1 | rRNA adenine N-6-methyltransferase | NC_002745.1125313.p0 | Protein | 5e-63 | 57 |
| ermC | NP_273130.1 | rRNA adenine N-6-methyltransferase | NC_009782.5559087.p0 | Protein | 5e-63 | 57 |
| ermC | NP_273130.1 | rRNA adenine N-6-methyltransferase | NC_002758.1121630.p0 | Protein | 5e-63 | 57 |
| ermC | NP_273130.1 | rRNA adenine N-6-methyltransferase | NC_002952.2859615.p0 | Protein | 5e-63 | 57 |
| ermC | NP_273130.1 | rRNA adenine N-6-methyltransferase | NC_002745.1123579.p0 | Protein | 5e-63 | 57 |
| ermC | NP_273130.1 | rRNA adenine N-6-methyltransferase | AM410044.gene14.p01 | Protein | 3e-57 | 51 |
| ermC | NP_273130.1 | rRNA adenine N-6-methyltransferase | AM903082.gene3.p01 | Protein | 3e-57 | 51 |
| ermC | NP_273130.1 | rRNA adenine N-6-methyltransferase | AM180355.1.gene2254. | Protein | 6e-57 | 50 |
| ermC | NP_273130.1 | rRNA adenine N-6-methyltransferase | AM180355.1.gene2259. | Protein | 6e-57 | 50 |
