Gene Information

Name : NMB0496 (NMB0496)
Accession : NP_273542.1
Strain : Neisseria meningitidis MC58
Genome accession: NC_003112
Putative virulence/resistance : Unknown
Product : hemolysin activator-like protein
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG2831
EC number : -
Position : 519142 - 520821 bp
Length : 1680 bp
Strand : +
Note : identified by similarity to EGAD:10212; match to protein family HMM PF03865

DNA sequence :
ATGGAAATTATTAACGATGCAGAACTTATCCGTTCCATGCAGCGTCAGCAGCACATAGATGCTGAATTGTTAACTGATGC
AAATGTCCGTTTCGAGCAACCATTGGAGAAGAACAATTATGTCCTGAGTGAAGATGAAACACCGTGTACTCGGGTAAATT
ACATTAGTTTAGATGATAAGACGGTGCGCAAATTTTCTTTTCTTCCTTCTGTGCTCATGAAAGAAACAGCTTTTAAAACT
GGGATGTGTTTAGGTTCCAATAATTTGAGCAGGCTACAAAAAGCCGCGCAACAGATACTGATCGTGCGTGGCTACCTCAC
TTCCCAAGCTATTATCCAACCACAGAATATGGATTCGGGAATTCTGAAATTACGGGTATCAGCAGGCGAAATAGGGGATA
TCCGCTATGAAGAAAAACGGGATGGGAAGTCTGCCGAGGGCAGTATTAGTGCATTCAATAACAAATTTCCCTTATATAGG
AACAAAATTCTCAATCTTCGCGATGTAGAGCAGGGCTTGGAAAACCTGCGTCGTTTGCCGAGTGTTAAAACAGATATTCA
GATTATACCGTCCGAAGAAGAAGGCAAAAGCGATTTACAGATCAAATGGCAGCAGAATAAACCCATACGGTTCAGTATCG
GTATAGATGATGCGGGCGGCAAAACGACCGGCAAATATCAAGGAAATGTCGCTTTATCGTTCGATAACCCTTTGGGCTTA
AGCGATTTGTTTTATGTTTCATATGGACGCGGTTTGGCGCACAAAACGGACTTGACTGATGCCACCGGTACGGAAACTGA
AAGCGGATCCAGAAGTTACAGCGTGCATTATTCGGTGCCCGTAAAAAAATGGCTGTTTTCTTTTAATCACAATGGACATC
GTTACCACGAAGCAACCGAAGGCTATTCCGTCAATTACGATTACAACGGCAAACAATATCAGAGCAGCCTGGCCGCCGAG
CGCATGCTTTGGCGTAACAGACTTCATAAAACTTCAGTCGGAATGAAATTATGGACACGCCAAACCTATAAATACATCGA
CGATGCCGAAATCGAAGTACAACGCCGCCGCTCTGCAGGCTGGGAAGCCGAATTGCGCCACCGTGCTTACCTCAACCGTT
GGCAGCTTGACGGCAAGTTGTCTTACAAACGCGGGACCGGCATGCGCCAAAGTATGCCTGCACCGGAAGAAAACGGCGGC
GATATTCTTCCAGGTACATCTCGTATGAAAATCATTACTGCCAGTTTGGACGCAGCCGCCCCATTTATTTTAGGCAAACA
GCAGTTTTTCTACGCAACCGCCATTCAAGCTCAATGGAACAAAACGCCGTTGGTTGCCCAAGATAAATTGTCAATCGGCA
GCCGCTACACCGTTCGCGGATTTGATGGGGAGCAGAGTCTTTTCGGAGAGCGAGGTTTCTACTGGCAGAATACTTTAACT
TGGTATTTTCATCCGAACCATCAGTTCTATCTCGGTGCGGACTATGGCCGCGTATCTGGCGAAAGTGCACAATATGTATC
GGGCAAGCAGCTGATGGGTGCAGTGGTCGGCTTCAGAGGAGGGCATAAAGTAGGCGGTATGTTTGCTTATGATCTGTTTG
CCGGCAAGCCGCTTCATAAACCCAAAGGCTTTCAGACGACCAACACCGTTTACGGCTTCAACTTGAATTACAGTTTCTAA

Protein sequence :
MEIINDAELIRSMQRQQHIDAELLTDANVRFEQPLEKNNYVLSEDETPCTRVNYISLDDKTVRKFSFLPSVLMKETAFKT
GMCLGSNNLSRLQKAAQQILIVRGYLTSQAIIQPQNMDSGILKLRVSAGEIGDIRYEEKRDGKSAEGSISAFNNKFPLYR
NKILNLRDVEQGLENLRRLPSVKTDIQIIPSEEEGKSDLQIKWQQNKPIRFSIGIDDAGGKTTGKYQGNVALSFDNPLGL
SDLFYVSYGRGLAHKTDLTDATGTETESGSRSYSVHYSVPVKKWLFSFNHNGHRYHEATEGYSVNYDYNGKQYQSSLAAE
RMLWRNRLHKTSVGMKLWTRQTYKYIDDAEIEVQRRRSAGWEAELRHRAYLNRWQLDGKLSYKRGTGMRQSMPAPEENGG
DILPGTSRMKIITASLDAAAPFILGKQQFFYATAIQAQWNKTPLVAQDKLSIGSRYTVRGFDGEQSLFGERGFYWQNTLT
WYFHPNHQFYLGADYGRVSGESAQYVSGKQLMGAVVGFRGGHKVGGMFAYDLFAGKPLHKPKGFQTTNTVYGFNLNYSF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
NMB1762 NP_274762.1 hemolysin activation protein HecB Not tested IHT-C Protein 2e-124 48