Gene Information

Name : mutS (NMB2160)
Accession : NP_275145.1
Strain : Neisseria meningitidis MC58
Genome accession: NC_003112
Putative virulence/resistance : Virulence
Product : DNA mismatch repair protein MutS
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0249
EC number : -
Position : 2269649 - 2272243 bp
Length : 2595 bp
Strand : +
Note : This protein performs the mismatch recognition step during the DNA repair process

DNA sequence :
ATGTCCAAATCCGCCGTTTCCCCAATGATGCAGCAATACCTCGGCATCAAAGCGCAACATACCGACAAACTGGTGTTTTA
CCGTATGGGCGATTTTTACGAGATGTTTTTCGACGATGCGGTAGAAGCGGCAAAACTTTTGGATATTACCCTGACCACGC
GCGGACAGGTGGATGGCGAGCCGGTCAAAATGGCAGGCGTGCCGTTTCACGCCGCCGAACAATATCTGGCGCGCCTGGTC
AAGTTGGGCAAAAGCGTGGCGATTTGCGAACAGGTCGGCGAAGTCGGCGCGGGCAAAGGGCCTGTGGAGCGCAAAGTCGT
GCGCATCGTAACGCCCGGCACGCTGACCGATTCCGCATTGCTGGAAGACAAGGAAACCAACCGCATCGTTGCCGTGTCCC
CCGACAAAAAATACATCGGTTTGGCGTGGGCATCGCTGCAAAGCGGCGAATTCAAAACCAAGCTGACAACTGTGGATAAA
TTGGACGACGAACTGGCGCGCCTGCAGGCGGCGGAAATTCTGTTGCCTGACAGTAAAAACGCACCGCAACTTCAGACGGC
ATCGGGTGTTACGCGCCTGAACGCGTGGCAGTTTGCCGCCGACGCGGGGGAAAAACTGCTGACGGAATATTTCGGCTGCC
AGGATTTGCGCGGCTTCGGTTTGGACGGCAAAGAACACGCCGTTGCGATTGGCGCGGCAGGTGCACTGTTGAACTATATC
CGTCTGACGCAAAACCTGATGCCGCAACATTTGGACGGCCTGTCGCTCGAAACCGACAGCCAATATATCGGTATGGATGC
CGCCACGCGCCGCAATCTCGAAATCACGCAAACCCTCTCCGGCAAAAAATCGCCGACCCTGATGTCCACGCTCGACCTTT
GCGCTACCCATATGGGCAGCCGCCTCTTGGCTCTCTGGCTGCACCACCCTTTACGCAACCGCGCCCACATCCGAGCGCGC
CAAGAAGCCGTTGCCGCGCTGGAAAGCCAATACAAACCCCTCCAGTGCCGTCTGAAAAGCATTGCCGACATCGAACGCAT
CGCCGCCCGTATTGCCGTGGGTAACGCCCGCCCGCGCGACCTCGCCGCCCTGCGCGACAGCCTGTTTGCCCTGTCCGAAA
TCGAATTGTCCGCCGAGTGCAGCAGTCTCTTAGGAACCCTCAAAGCCGTTTTCCCGGAAAACCTATCCACAGCCGAACAG
CTCCGCCAAGCCATTTTGCCCGAACCTTCCGTCTGGCTGAAAGACGGCAATGTCATCAACCACGGTTTTCATCCCGAACT
GGACGAATTGCGCCGCATTCAAAACCATGGCGACGAATTTTTGCTGGATTTGGAAGCCAAGGAACGCGAACGTACCGGTT
TGTCCACACTTAAAGTCGAGTTCAACCGCGTTCACGGCTTTTACATTGAATTGTCCAAAACCCAAGCCGAACAAGCACCT
GCCGACTACCAACGCCGGCAAACCCTTAAAAACGCCGAACGCTTCATCACGCCGGAACTGAAAGCCTTTGAAGACAAAGT
GCTGACTGCTCAAGAGCAAGCCCTCGCCTTAGAAAAACAACTCTTTGACGGCGTATTGAAAAACCTTCAGACGGCATTGC
CGCAGCTTCAAAAAGCCGCCAAAGCCGCCGCCGCGCTGGACGTGTTGTCCACATTTTCAGCCTTGGCAAAAGAGCGGAAC
TTCGTCCGCCCCGAGTTTGCCGACTATCCGGTTATCCACATCGAAAACGGCCGCCATCCCGTTGTCGAACAGCAGGTACG
CCACTTCACCGCCAACCACACCGACCTTGACCACAAACACCGCCTCATGCTGCTCACCGGCCCCAATATGGGCGGCAAAT
CCACCTACATGCGCCAAGTCGCGCTGATTGTTTTATTGGCACACACCGGCTGTTTTGTGCCTGCCGATGCCGCCACAATC
GGGCCCATCGATCAAATCTTCACCCGCATCGGCGCATCGGACGACCTCGCCTCCAACCGCTCCACTTTCATGGTCGAAAT
GAGCGAAACCGCCTACATCCTGCATCACGCCACCGAACAAAGCCTTGTTTTAATGGACGAAGTCGGACGTGGTACTTCCA
CTTTCGACGGCCTCGCCCTCGCGCACGCCGTTGCCGAACACCTGCTGCAAAAAAACAAATCCTTCAGCCTGTTTGCTACC
CACTATTTCGAGCTGACCTACCTGCCCGAAGCCCACACCGCCGCCGTCAATATGCACCTTTCCGCGCTCGAACAGGGACA
GGACATCGTTTTCCTGCACCAAATCCAACCGGGTCCCGCCGGTAAAAGCTACGGCATTGCCGTCGCCAAACTCGCCGGCC
TGCCTGTACGCGCATTGAAATCCGCCCAAAAGCATTTGAACGGACTGGAAAACCAAGCCGCCGCGAACCGTCCCCAACTG
GATATTTTCAGTACCATGCCGTCTGAAAAAGGAGATGAACCGAATGTGGGCAACTTTGTGGATAAAGCAGAGGAAAAACA
TTTTGAAGGTATATTGGCAGCAGCCTTGGAAAAACTCGATCCCGACAGCCTGACCCCGCGCGAAGCATTGTCAGAACTGT
ACCGTCTGAAAGATTTGTGCAAATCCGTATCTTAA

Protein sequence :
MSKSAVSPMMQQYLGIKAQHTDKLVFYRMGDFYEMFFDDAVEAAKLLDITLTTRGQVDGEPVKMAGVPFHAAEQYLARLV
KLGKSVAICEQVGEVGAGKGPVERKVVRIVTPGTLTDSALLEDKETNRIVAVSPDKKYIGLAWASLQSGEFKTKLTTVDK
LDDELARLQAAEILLPDSKNAPQLQTASGVTRLNAWQFAADAGEKLLTEYFGCQDLRGFGLDGKEHAVAIGAAGALLNYI
RLTQNLMPQHLDGLSLETDSQYIGMDAATRRNLEITQTLSGKKSPTLMSTLDLCATHMGSRLLALWLHHPLRNRAHIRAR
QEAVAALESQYKPLQCRLKSIADIERIAARIAVGNARPRDLAALRDSLFALSEIELSAECSSLLGTLKAVFPENLSTAEQ
LRQAILPEPSVWLKDGNVINHGFHPELDELRRIQNHGDEFLLDLEAKERERTGLSTLKVEFNRVHGFYIELSKTQAEQAP
ADYQRRQTLKNAERFITPELKAFEDKVLTAQEQALALEKQLFDGVLKNLQTALPQLQKAAKAAAALDVLSTFSALAKERN
FVRPEFADYPVIHIENGRHPVVEQQVRHFTANHTDLDHKHRLMLLTGPNMGGKSTYMRQVALIVLLAHTGCFVPADAATI
GPIDQIFTRIGASDDLASNRSTFMVEMSETAYILHHATEQSLVLMDEVGRGTSTFDGLALAHAVAEHLLQKNKSFSLFAT
HYFELTYLPEAHTAAVNMHLSALEQGQDIVFLHQIQPGPAGKSYGIAVAKLAGLPVRALKSAQKHLNGLENQAAANRPQL
DIFSTMPSEKGDEPNVGNFVDKAEEKHFEGILAAALEKLDPDSLTPREALSELYRLKDLCKSVS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
mutS AAA80578.1 DNA mismatch repair protein Virulence SPI-1 Protein 6e-167 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mutS NP_275145.1 DNA mismatch repair protein MutS VFG0562 Protein 1e-176 50