Gene Information

Name : lspA (NMB1832)
Accession : NP_274829.1
Strain : Neisseria meningitidis MC58
Genome accession: NC_003112
Putative virulence/resistance : Unknown
Product : lipoprotein signal peptidase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0597
EC number : 3.4.23.36
Position : 1928781 - 1929308 bp
Length : 528 bp
Strand : -
Note : lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis

DNA sequence :
ATGGTACTCTTTTACCGGCTGTTGAAAAATATGTCTTCATCTGTTTCAAGTAAAACGCGCTATTGGGTATTGGCACTTGC
CGCCATCGTGCTGGACCAGTGGTCGAAGTGGGCGGTGCTGTCGTCGTTTCAGTATCGGGAACGCGTCAATGTCATTCCTT
CCTTTTTCGATCTGACGCTGGTGTACAACCCGGGTGCGGCGTTCAGCTTCCTTGCCGATCAGGGCGGCTGGCAAAAATAC
TTTTTTTTGGTGCTGGCGGTGGCGGTGAGCGCGTATTTGGTACGCGCCATCTTGCGCGATGAGTTTGCAACCCTCGGCAA
AACGGGTGCGGCAATGATTATCGGCGGTGCGTTAGGCAATGTCATCGACCGCCTGATACACGGTCATGTCGTCGATTTCT
TATTGTTTTATTGGCAAAATTGGTTTTATCCCGCCTTTAATATTGCCGACAGCTTTATCTGCGTCGGTGCGGTGTTGGCG
GTGTTGGACAACATCGTCCACCGTAAAACCCAAGAAGAAAAATATTGA

Protein sequence :
MVLFYRLLKNMSSSVSSKTRYWVLALAAIVLDQWSKWAVLSSFQYRERVNVIPSFFDLTLVYNPGAAFSFLADQGGWQKY
FFLVLAVAVSAYLVRAILRDEFATLGKTGAAMIIGGALGNVIDRLIHGHVVDFLLFYWQNWFYPAFNIADSFICVGAVLA
VLDNIVHRKTQEEKY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ACICU_00236 YP_001844895.1 lipoprotein signal peptidase Not tested AbaR20 Protein 3e-16 45
lspA ACN81031.1 lipoprotein signal peptidase Not tested AbaR5 Protein 3e-16 45
lspA CAJ77096.1 Lipoprotein signal poeptidase Not tested AbaR1 Protein 2e-16 45
lspA ADZ05771.1 lipoprotein signal peptidase Not tested AbaR11 Protein 2e-16 45
lspA AGK36655.1 lipoprotein signal peptidase Not tested AbaR26 Protein 2e-16 45
lspA ADI24143.1 lipoprotein signal peptidase Not tested AbaR1 Protein 2e-14 44
lspA CAJ77023.1 lipoprotein signal peptidase Not tested AbaR1 Protein 2e-14 44
lspA ACS32043.1 lipoprotein signal peptidase Not tested AbaR5 Protein 4e-14 44
lspA AAN62189.1 putative lipoprotein signal peptidase LspA Not tested PAGI-2(C) Protein 2e-12 43