Gene Information

Name : NMB1762 (NMB1762)
Accession : NP_274762.1
Strain : Neisseria meningitidis MC58
Genome accession: NC_003112
Putative virulence/resistance : Unknown
Product : hemolysin activation protein HecB
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG2831
EC number : -
Position : 1841413 - 1843200 bp
Length : 1788 bp
Strand : -
Note : identified by similarity to EGAD:149243; match to protein family HMM PF03865

DNA sequence :
ATGAAACTTCCTTTATCCTATTTGCCTAATATTCGCTTTTTGTCTTGGTGCTGCTTATTGGCAGGTATCATTGCTCCTGC
TACTTTGTTGGCCTCCCCCAACCCTGCCGAAATCCGTATGCAGCAAGATATTCAGCAACGCCAACGCGAAGAGCAGTTGC
GCCAAACCATGCAGCCTGAAAGCGATGTGCGTTTGCATCAAAAAAACACGGGGGAAACGGTTAATCAGTTGATGGGCGAT
GACAGCAGCCAACCGTGTTTTGCCATTAACGAAGTGGTGTTGGAAGGCGAACACCATGCTCGGTTTCAGTTTGCCCTAAA
ACGTGCCTTGCGCGAAACGGGTTTTCAGGCTGGCAAGTGTCTGCATGCGGGCAACATTAATCAAATCATGTCCTTAGCAC
AAAATGCTTTGATCGGCAGGGGATATACCACGACCCGTATCTTGGCTGCGCCACAGGATTTGAATAGTGGCAAGCTTCAA
TTAACCCTGATACCGAGCTATCTGCGCTCCATACGAATCGATCGGTCTAACGATGATCAAACCCATGCAGGACGTATTGC
AGCATTCCAGAACAAATTTCCCACCCGCTCGAACGATCTGTTGAATCTGCGTGATTTGGAACAAGGACTGGAAAATCTCA
AACGTCTCCCGACTGCGGAAGCCGATCTCCAAATCGTTCCCGTAGAGGGAGAACCAAACCAAAGTGATGTCGTGGTGCAA
TGGCGGCAACGTCTGCTGCCCTACCGTGTGAGTGTGGGGATGGATAATTCGGGTAGTGAGGCGACAGGAAAATACCAAGG
AAATATCACTTTCTCTGCCGACAATCCTTTGGGACTGAGTGATATGTTCTATGTAAATTATGGACGTTCGATTGGCGGTA
CGCCCGATGAGGAAAGTTTTGACGGCCATCGCAAAGAAGGCGGATCAAACAATTACGCCGTACATTATTCAGCCCCTTTC
GGTAAATGGACATGGGCATTCAATCACAATGGCTACCGTTACCATCAGGCAGTTTCCGGATTATCGGAAGTCTATGACTA
TAATGGAAAAAGTTACAATACTGATTTCGGCTTCAACCGCCTGTTGTATCGTGATGCCAAACGCAAAACCTATCTCGGTG
TAAAACTGTGGATGAGGGAAACAAAAAGTTACATTGATGATGCCGAACTGACTGTACAACGGCGTAAAACTGCGGGTTGG
TTGGCAGAACTTTCCCACAAAGAATATATCGGTCGCAGTACGGCAGATTTTAAGTTGAAATATAAACGCGGCACCGGCAT
GAAAGATGCTCTGCGCGCGCCTGAAGAAGCCTTTGGCGAAGGCACGTCACGTATGAAAATTTGGACGGCATCGGCTGATG
TAAATACTCCTTTTCAAATCGGTAAACAGCTATTTGCCTATGACACATCCGTTCATGCACAATGGAACAAAACCCCGCTA
ACATCGCAAGACAAACTGGCTATCGGCGGACACCACACCGTACGTGGCTTCGACGGTGAAATGAGTTTGTCTGCCGAGCG
GGGATGGTATTGGCGCAACGATTTGAGCTGGCAATTTAAACCAGGCCATCAGCTTTATCTTGGGGCTGATGTAGGACATG
TTTCAGGACAATCCGCCAAATGGTTATCGGGCCAAACTCTAGTCGGCACAGCAATTGGGATACGCGGGCAGATAAAGCTT
GGCGGCAACCTGCATTACGATATATTTACCGGCCGCGCATTGAAAAAGCCCGAATTTTTCCAATCAAGGAAATGGGCAAG
CGGTTTTCAGGTAGGCTATACGTTTTAA

Protein sequence :
MKLPLSYLPNIRFLSWCCLLAGIIAPATLLASPNPAEIRMQQDIQQRQREEQLRQTMQPESDVRLHQKNTGETVNQLMGD
DSSQPCFAINEVVLEGEHHARFQFALKRALRETGFQAGKCLHAGNINQIMSLAQNALIGRGYTTTRILAAPQDLNSGKLQ
LTLIPSYLRSIRIDRSNDDQTHAGRIAAFQNKFPTRSNDLLNLRDLEQGLENLKRLPTAEADLQIVPVEGEPNQSDVVVQ
WRQRLLPYRVSVGMDNSGSEATGKYQGNITFSADNPLGLSDMFYVNYGRSIGGTPDEESFDGHRKEGGSNNYAVHYSAPF
GKWTWAFNHNGYRYHQAVSGLSEVYDYNGKSYNTDFGFNRLLYRDAKRKTYLGVKLWMRETKSYIDDAELTVQRRKTAGW
LAELSHKEYIGRSTADFKLKYKRGTGMKDALRAPEEAFGEGTSRMKIWTASADVNTPFQIGKQLFAYDTSVHAQWNKTPL
TSQDKLAIGGHHTVRGFDGEMSLSAERGWYWRNDLSWQFKPGHQLYLGADVGHVSGQSAKWLSGQTLVGTAIGIRGQIKL
GGNLHYDIFTGRALKKPEFFQSRKWASGFQVGYTF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
NMB1762 NP_274762.1 hemolysin activation protein HecB Not tested IHT-C Protein 0.0 100
S1 AAQ19124.1 putative hemolysin activator HlyB Not tested PAI I CL3 Protein 1e-83 41