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Name : thyA (NMB1709) Accession : NP_274712.1 Strain : Neisseria meningitidis MC58 Genome accession: NC_003112 Putative virulence/resistance : Unknown Product : thymidylate synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0207 EC number : 2.1.1.45 Position : 1784892 - 1785686 bp Length : 795 bp Strand : - Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived DNA sequence : ATGAAAGCCTATTTGGACTTGATGCGCCACGTCCTCGACAACGGTACGGACAAATCAGACCGCACCGGTACGGGTACGCG CTCCGTATTCGGTTATCAGATGCGTTTTGACTTGGGCAAAGGTTTTCCGCTGCTGACGACCAAAAAGCTGCATCTGCGTT CGATTATCCACGAGCTGCTTTGGTTTCTCAAAGGCGATACCAATATCAAATACCTAAAGGACAACAATGTTTCCATTTGG GACGAGTGGGCGGACGAAAACGGCGACTTAGGCCCGGTTTACGGCTACCAGTGGCGTAACTGGCCCGCGCCCGACGGCAG GCATATCGACCAAATCGCCAATGTGCTGGAACAAATCAAGAAGAATCCCGACTCGCGCCGCCTGATTGTATCGGCGTGGA ATCCGGCTTTGGTCGATGAAATGGCCTTGCCGCCCTGCCACGCGCTGTTTCAGTTTTACGTTGCCGACGGCAAACTGTCC TGCCAGCTTTACCAGCGTAGTGCAGATATTTTCCTTGGTGTGCCGTTTAATATTGCCAGCTACGCATTGTTGACCATGAT GATGGCGCAAGTGTGCGGATTGGAGGCGGGCGAGTTTGTCCATACGTTTGGCGACGCGCATTTGTACCGCAACCATTTCG AGCAGGCCGCATTGCAGTTGGAACGCGAACCGCGCGCCTTGCCAGTGATGAAAATCAATCCTGAAGTCAAAGATTTGTTT TCCTTCAAGTTTGAAGATTTCGAGTTGGAAGGTTACGACCCTCATCCGCATATCAAGGCGGCAGTGTCGGTTTAG Protein sequence : MKAYLDLMRHVLDNGTDKSDRTGTGTRSVFGYQMRFDLGKGFPLLTTKKLHLRSIIHELLWFLKGDTNIKYLKDNNVSIW DEWADENGDLGPVYGYQWRNWPAPDGRHIDQIANVLEQIKKNPDSRRLIVSAWNPALVDEMALPPCHALFQFYVADGKLS CQLYQRSADIFLGVPFNIASYALLTMMMAQVCGLEAGEFVHTFGDAHLYRNHFEQAALQLEREPRALPVMKINPEVKDLF SFKFEDFELEGYDPHPHIKAAVSV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| thyA | YP_001800914.1 | thymidylate synthase | Not tested | Not named | Protein | 6e-83 | 65 |
