Gene Information

Name : serS (NMB1684)
Accession : NP_274688.1
Strain : Neisseria meningitidis MC58
Genome accession: NC_003112
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1760633 - 1761928 bp
Length : 1296 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGATATCCAATTGCTCCGCAGCAACACCGCCGCCGTTGCCGAACGGCTTGCACGGCGCGGTTATGACTTTGATAC
CGCACGTTTTGACACACTGGAAGAACGACGCAAGTCCGTTCAGGTGAAAACCGAAGAATTACAGGCCTCGCGCAACAGCA
TTTCCAAACAAATCGGCGCACTGAAAGGTCAGGGCAAACACGAAGAAGCGCAGGCGGCCATGAATCAGGTTGCCCAAATC
AAAACCGATTTGGAACAGGCTGCCGCCGATTTGGATGCCGTTCAAAAAGAATTGGACGCATGGTTGTTGAGCATACCTAA
CCTGCCGCACGAAAGCGTACCTGCCGGTAAAGACGAAACCGAAAACGTCGAAGTCCGCAAAGTCGGCACCCCGCGCGAAT
TTGACTTTGAAATCAAAGACCATGTCGATTTGGGCGAACCTTTGGGTTTGGATTTTGAAGGCGGTGCAAAACTCTCCGGC
GCACGATTTACCGTGATGCGCGGACAAATCGCCCGTCTGCACCGCGCCTTGGCACAGTTCATGCTGGATACGCACACGCT
GCAACACGGCTACACCGAGCATTACACGCCTTATATCGTTGACGATACGACGCTGCAAGGTACGGGCCAACTACCAAAAT
TTGCGGAAGATCTGTTCCACGTTACCCGTGGCGGCGACGAAACCAAAACCACCCAATACCTGATTCCGACAGCCGAAGTT
ACCCTGACCAATACCGTTGCCGACAGCATTATCCCGTCCGAACAACTGCCGCTGAAGCTGACCGCGCATTCGCCCTGTTT
CCGCAGCGAGGCGGGTTCGTACGGCAAAGACACGCGCGGTCTGATTCGCCAGCACCAGTTCGACAAAGTGGAAATGGTTC
AAATCGTTCATCCCGAAAAATCATACGAAACGCTGGAAGAAATGGTCGGCCATGCCGAAAACATCCTGAAGGCTTTGGAA
CTGCCCTACCGCGTGATTACCCTGTGTACCGGCGACATGGGCTTCGGCGCGGCAAAAACGTATGACTTGGAAGTTTGGGT
GCCGGCGCAAAATACCTACCGCGAAATCTCAAGCTGCTCCAACTGCGAAGATTTCCAAGCCCGCCGCCTGAAGGCGCGTT
TCAAAGACGAAAACGGCAAAAACCGCTTGGTACATACTTTGAACGGCTCCGGCTTGGCTGTCGGCAGAACGCTGGTCGCC
GTATTGGAAAACCATCAAAACGCCGACGGCAGCATCAACATCCCTGCCGCACTGCAACCGTATATGGGCGGTGTTGCCAA
GTTGGAAGTCAAATAA

Protein sequence :
MLDIQLLRSNTAAVAERLARRGYDFDTARFDTLEERRKSVQVKTEELQASRNSISKQIGALKGQGKHEEAQAAMNQVAQI
KTDLEQAAADLDAVQKELDAWLLSIPNLPHESVPAGKDETENVEVRKVGTPREFDFEIKDHVDLGEPLGLDFEGGAKLSG
ARFTVMRGQIARLHRALAQFMLDTHTLQHGYTEHYTPYIVDDTTLQGTGQLPKFAEDLFHVTRGGDETKTTQYLIPTAEV
TLTNTVADSIIPSEQLPLKLTAHSPCFRSEAGSYGKDTRGLIRQHQFDKVEMVQIVHPEKSYETLEEMVGHAENILKALE
LPYRVITLCTGDMGFGAAKTYDLEVWVPAQNTYREISSCSNCEDFQARRLKARFKDENGKNRLVHTLNGSGLAVGRTLVA
VLENHQNADGSINIPAALQPYMGGVAKLEVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 3e-102 55