Gene Information

Name : argF (NMB1573)
Accession : NP_274579.1
Strain : Neisseria meningitidis MC58
Genome accession: NC_003112
Putative virulence/resistance : Unknown
Product : ornithine carbamoyltransferase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0078
EC number : 2.1.3.3
Position : 1634701 - 1635696 bp
Length : 996 bp
Strand : +
Note : catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway

DNA sequence :
GTGAACCTGAAAAACCGCCATTTTCTGAAACTTTTAGACTTCACGCCGGAAGAAATCACCGCCTACCTCGACCTTGCCGC
CGAATTGAAAGCCGCCAAAAAAGCAGGGCGCGAGATTCAGCGGATGAAAGGGAAAAACATCGCCCTGATTTTTGAAAAAA
CCTCTACTCGGACGCGCTGCGCGTTTGAAGTCGCCGCGCGCGATCAAGGCGCGGGAGTGACTTATTTAGAGCCGTCCGCC
AGCCAAATCGGGCATAAGGAAAGCATCAAAGACACCGCCCGCGTGTTGGGCAGGATGTACGATGCCATCGAATATCGCGG
TTTCGGTCAGGAAGTTGTTGAAGAATTGGCGAAATACGCGGGCGTACCCGTGTTCAACGGGCTGACCAACGAGTTCCATC
CCACACAAATGCTTGCCGACGCACTGACTATGCGCGAACACAGCGGCAAACCTTTGAACCAAACCGCGTTTGCCTACGTC
GGCGACGCGCGTTACAACATGGGCAATTCCCTGCTGATTTTAGGGGCAAAATTGGGGATGGACGTGCGTATCGGCGCACC
GCAAAGCCTGTGGCCGTCTGAAGGCATTATTGCCGCCGCACACGCCGCCGCCAAAGAAACCGGCGCAAAAATTACCCTGA
CCGAAAACGCGCATGAAGCCGTGAAGAATGTTGATTTTATTCATACCGATGTGTGGGTCAGCATGGGCGAGCCGAAAGAA
GTCTGGCAGGAACGCATCGATTTGCTGAAAGATTACCGCGTTACGCCCGAACTGATGGCGGCATCGGGCAATCCGCAAGT
CAAATTCATGCACTGCCTGCCCGCCTTCCACAACCGCGAAACCAAAGTCGGCGAATGGATTTACGAAACCTTCGGGCTGA
ACGGTGTGGAAGTTACAGAAGAAATATTCGAAAGCCCCGCCAGCATCGTGTTCGATCAGGCGGAAAACCGTATGCACACG
ATTAAAGCGGTAATGGTCGCGGCTCTGGGCGACTGA

Protein sequence :
MNLKNRHFLKLLDFTPEEITAYLDLAAELKAAKKAGREIQRMKGKNIALIFEKTSTRTRCAFEVAARDQGAGVTYLEPSA
SQIGHKESIKDTARVLGRMYDAIEYRGFGQEVVEELAKYAGVPVFNGLTNEFHPTQMLADALTMREHSGKPLNQTAFAYV
GDARYNMGNSLLILGAKLGMDVRIGAPQSLWPSEGIIAAAHAAAKETGAKITLTENAHEAVKNVDFIHTDVWVSMGEPKE
VWQERIDLLKDYRVTPELMAASGNPQVKFMHCLPAFHNRETKVGEWIYETFGLNGVEVTEEIFESPASIVFDQAENRMHT
IKAVMVAALGD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0103 NP_763658.1 ornithine carbamoyltransferase Not tested SCCpbp4 Protein 2e-85 60
argF NP_645867.1 ornithine carbamoyltransferase Not tested vSa¥ã Protein 1e-86 58
arcB1 YP_186044.1 ornithine carbamoyltransferase Not tested vSa¥ã Protein 2e-86 57
argF YP_493760.1 ornithine carbamoyltransferase Not tested vSa¥ã Protein 2e-86 57
argF NP_371693.1 ornithine carbamoyltransferase Not tested vSa¥ã Protein 1e-86 57
argF NP_374285.1 ornithine carbamoyltransferase Not tested vSa¥ã Protein 1e-86 57
SAKOR_01090 YP_008491278.1 Ornithine carbamoyltransferase Not tested vSa¥ã Protein 1e-86 57