Gene Information

Name : rph (NMB1499)
Accession : NP_274507.1
Strain : Neisseria meningitidis MC58
Genome accession: NC_003112
Putative virulence/resistance : Unknown
Product : ribonuclease PH
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0689
EC number : 2.7.7.56
Position : 1549458 - 1550186 bp
Length : 729 bp
Strand : -
Note : RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs

DNA sequence :
ATGCCTGATTACATCCGCATCTCGCGCGCCGCCGACAGCCTGCGCGATATCAAAATCACCCCTCATTTCCTGCCGCATAC
GGACGGTTCGTGCCTTATTGAATGCGGCAATACCAAAGTGATTTGTACCGCTTCCATAGATGAAAACGTCCCGCCGTTTC
TGCGCGGTAAAAACCAAGGCTGGGTAACGGCGGAATACGGGATGCTGCCTGCCTCAACTGCTTCCCGGATGCTCCGCGAA
GCTTCGGCGGGCAAACAGTCCGGGCGCACACAAGAAATCCAACGTTTGATCGGGCGTTCCCTGCGCGCGGTCGTGGATAT
GGAAAAACTCGGTGAACGACAAATCTTGATTGACTGCGATGTGATTCAGGCAGACGGCGGTACGCGCACGGCTTCGATTA
CCGGTGCGTTTGTCGCGCTGCAAATCGCCGTCGGCAAACTGGTTTCAGACGGCATTTTGAGTGAAAACCCCATCCGCGAA
GCCGTTGCCGCTGTGTCAGTAGGCGTAGTGAACGGCGTGCCGCTTTTGGATTTGGATTATCCCGAAGACTCCGGTTGCGA
CAGTGATGTGAATATCGTCATGACCGCATCGGGAAAAATCATCGAAATACAGGGGACGGCGGAAGACGCGCCGTTCAGTT
TGGACGAATTGGGCAAACTGGTTGCACTGGCGCAAAAAGGCATAGGCGAACTGCTGCAACACCAGCAAAATGCGTTGTCC
GCCGCCTGA

Protein sequence :
MPDYIRISRAADSLRDIKITPHFLPHTDGSCLIECGNTKVICTASIDENVPPFLRGKNQGWVTAEYGMLPASTASRMLRE
ASAGKQSGRTQEIQRLIGRSLRAVVDMEKLGERQILIDCDVIQADGGTRTASITGAFVALQIAVGKLVSDGILSENPIRE
AVAAVSVGVVNGVPLLDLDYPEDSGCDSDVNIVMTASGKIIEIQGTAEDAPFSLDELGKLVALAQKGIGELLQHQQNALS
AA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
rph YP_001800860.1 ribonuclease PH Not tested Not named Protein 8e-53 54