Gene Information

Name : NMB1473 (NMB1473)
Accession : NP_274482.1
Strain : Neisseria meningitidis MC58
Genome accession: NC_003112
Putative virulence/resistance : Unknown
Product : aminotransferase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0436
EC number : 2.6.1.2
Position : 1523436 - 1524650 bp
Length : 1215 bp
Strand : -
Note : broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor

DNA sequence :
ATGGATAAATTTCCCAAGTCTGCAAAGCTCGATCACGTCTGTTACGACATACGCGGGCCGGTTCACAAAAAAGCCCTTCA
GTTGGAAGAGGAGGGCAATAAAATCCTTAAACTCAATATCGGCAACCCTGCGCCGTTCGGCTTTGAAGCCCCTGATGAAA
TCTTGGTCGATGTCATCCGCAACCTGCCGACTTCGCAAGGCTATTGCGATTCTAAAGGGCTGTATTCCGCCCGCAAAGCC
ATTGTTCACTACTATCAGACCAAAGGTTTGCGCGATATTACGGTTGATGATGTCTATATCGGCAACGGCGTGTCCGAGCT
GATTACGATGTCTATGCAGGCATTGCTCAACGACGGCGACGAAATCCTGATTCCCGCGCCCGACTATCCCTTGTGGACGG
CGGCGGCAACGCTTGCGGGCGGTACGGTACGCCATTATCTGTGCGACGAAGAAAACGGCTGGTTCCCCAACCTTGCCGAT
ATGGAAGCCAAAATCACGCCCAAAACCAAAGCCATCGTCGTCATCAATCCCAATAATCCGACAGGCGCGGTGTACAGCAG
GGAAATCCTGTTGGAAATCGCCGAACTGGCGCGCAAGCACGGTTTGATTATTTTCGCCGACGAGATTTACGACAAAATCC
TTTATGACGGCGCGGTTCACCACCACATCGCCGCGCTTGCCCCCGACCTTTTGACGGTAACGTTCAACGGTTTGTCCAAA
GCCTACCGTGTAGCCGGATTCCGCCAAGGCTGGATGGTGCTCAACGGGCCGAAACATCATGCAAAAGGTTACATCGAGGG
TTTGGATATGCTCTCGTCTATGCGCCTGTGTGCCAATACGCCGATGCAGCACGCGATTCAGACGGCATTGGGCGGCTATC
AGAGCATCAACGAATTCATTTTGCCCGGCGGACGGCTTTTGGAACAGCGCAACAGGGCGTGGGAACTGGTCAACCAGATT
CCCGGCGTATCCTGCGTCAAACCGATGGGCGCGATGTATATGTTCCCAAAAATCGATACCGAAATGTACCGTATCCGCGA
TGACATGAAATTCGTTTACGATTTGCTGGTGCGCGAAAAAGTCTTGCTGGTGCAGGGAACGGGGTTTAATTGGATCAAGC
CCGACCATTTCCGCATTGTTACGCTGCCTTACGTCCATCAGATTGAAGAGGCGATGGGCAGGCTGGCAAGATTCCTGCAA
ACCTACCGCCAATAA

Protein sequence :
MDKFPKSAKLDHVCYDIRGPVHKKALQLEEEGNKILKLNIGNPAPFGFEAPDEILVDVIRNLPTSQGYCDSKGLYSARKA
IVHYYQTKGLRDITVDDVYIGNGVSELITMSMQALLNDGDEILIPAPDYPLWTAAATLAGGTVRHYLCDEENGWFPNLAD
MEAKITPKTKAIVVINPNNPTGAVYSREILLEIAELARKHGLIIFADEIYDKILYDGAVHHHIAALAPDLLTVTFNGLSK
AYRVAGFRQGWMVLNGPKHHAKGYIEGLDMLSSMRLCANTPMQHAIQTALGGYQSINEFILPGGRLLEQRNRAWELVNQI
PGVSCVKPMGAMYMFPKIDTEMYRIRDDMKFVYDLLVREKVLLVQGTGFNWIKPDHFRIVTLPYVHQIEEAMGRLARFLQ
TYRQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aspC YP_005682179.1 Aminotransferase AlaT Not tested PiCp 7 Protein 2e-122 66
aspC YP_005684271.1 Aminotransferase AlaT Not tested PiCp 7 Protein 2e-122 66
aspC YP_003784329.1 aspartate aminotransferase Not tested PiCp 7 Protein 2e-122 66
aspC YP_005686363.1 Aminotransferase AlaT Not tested PiCp 7 Protein 2e-122 66