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Name : tktA (NMB1457) Accession : NP_274468.1 Strain : Neisseria meningitidis MC58 Genome accession: NC_003112 Putative virulence/resistance : Unknown Product : transketolase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0021 EC number : 2.2.1.1 Position : 1504457 - 1506436 bp Length : 1980 bp Strand : + Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo DNA sequence : ATGTCTCAACTGGCAAACGCAATCCGCTTCCTCTCGGCCGATGCCGTTCAAAAAGCCAATTCCGGCCACCCCGGCGCGCC TATGGGTATGGCGGAAATGGCGGAAACATTGTGGACGAAATTCCTCAATCACAACCCCGCCAACCCCAAATTCTACAACC GCGACCGCTTCGTCCTCTCCAACGGCCACGCGTCTATGCTGTTGTACAGCCTGCTGCACCTGACCGGCTACAACCTAAGC ATTGAAGACTTGAAAAACTTCCGCCAACTGCACAGCAAAACCCCCGGCCATCCCGAATACGGCTACACCGACGGCGTGGA AACCACGACCGGCCCGTTGGGGCAAGGGATTGCCAACGCGGTGGGTATGGCATTGGCAGAAAAAATCCTTGCCGCCGAAT TTAATAAAGACGGTTTGAACATCGTCGATCATTACACCTACGTCTTTATGGGCGACGGCTGTCTGATGGAAGGCGTATCG CACGAAGCCTGTTCGCTCGCCGGCACCTTGGGCTTGGGCAAACTGATTGTTTTATATGATGACAACAATATTTCCATTGA TGGTAAAGTGGACGGCTGGTTTACCGAAAACATCCCGCAACGCTTTGAAAGCTACGGCTGGCACGTCGTTCCCAATGTAA ACGGTCATGACACCGCCGCCATTCAAGCCGCCATCGAAGCCGCACGTGCCGAAACCGGCAAACCGTCCATCATCTGCTGC AAAACCTTAATCGGCAAAGGCAGTGCCAACAAAGAAGGCAGCCACAAAACCCACGGCGCACCTTTGGGCGCGGACGAAAT CGAAGCCACGCGCAAACATTTGGGCTGGACTTACCCCGCCTTTGAAATCCCGCAAGAAATTTACGATGCGTGGAATGCCA AAGAACAAGGCGCGAAACTGGAAGCCGACTGGAACGAACTGTTCGCGCAATATCAAGCCAAATATCCTGCCGAAGCCGCA GAATTTGTGCGCCGTATGGATAAAAAGCTGCCGGACAATTTCGATGAATACGTTCAAGCCGCATTGAAAGAAGTGTGCGC CAAAGCCGAAACCATCGCCACCCGCAAAGCCAGCCAAAACAGCATCGAAATCTTGGCAAAAGAGTTGCCTGAATTGGTAG GCGGTTCTGCCGACCTGACCCCGTCCAATCTGACCGACTGGTCAAACAGCGTCTCCGTTACCCGCGACAAAGGCGGCAAC TACATCCACTACGGCGTGCGCGAGTTCGGCATGGGTGCGATTATGAACGGTTTGGTATTGCACGGCGGCGTAAAACCCTT CGGCGCGACTTTCCTGATGTTCAGCGAATACGAGCGCAATGCCCTGCGTATGGCTGCGTTGATGAAAATCAACCCTGTAT TTGTGTTTACCCACGATTCCATCGGTTTGGGCGAAGACGGCCCGACCCATCAACCGATTGAGCAAACCGCCACCCTGCGC CTGATTCCGAATATGGACGTATGGCGGCCGTGCGACACCGCCGAATCCTTGGTGGCTTGGGCAGAAGCCGTCAAAGCCGC CGATCACCCGTCCTGCCTGATTTTCAGCCGTCAAAACCTGAAATTCCAAGCGCGCAGCGAGCAACAACTGAACGACATCA AACGCGGCGGCTACGTCATCAGCGAAGCCCAAGGCAACGCCCAAGCCGTCATCATTGCCACCGGCTCAGAAGTCGAGCTG GCTTTGGAAGCGCAAAAAGCCCTCGCCGCGCAAAACATCGCCGTGCGCGTCGTTTCCATGCCGTCCACCAACGTATTCGA CCGCCAAGACGCCGCCTATCAAGCCGCCGTCCTGCCCGAAGGCCTGCCGCGCATCGCCGTAGAAGCCGGACACGCCGACG GCTGGTACAAATATGTCGGACTGAACGGCGCAGTCGTCGGCATCAACCGCTTCGGCGAATCCGCCCCTGCCGATTTACTC TTCAAAGCATTCGGCTTTACCGTGGACAATGTGGTTGATACGGTGAAATCCGTGCTGTAA Protein sequence : MSQLANAIRFLSADAVQKANSGHPGAPMGMAEMAETLWTKFLNHNPANPKFYNRDRFVLSNGHASMLLYSLLHLTGYNLS IEDLKNFRQLHSKTPGHPEYGYTDGVETTTGPLGQGIANAVGMALAEKILAAEFNKDGLNIVDHYTYVFMGDGCLMEGVS HEACSLAGTLGLGKLIVLYDDNNISIDGKVDGWFTENIPQRFESYGWHVVPNVNGHDTAAIQAAIEAARAETGKPSIICC KTLIGKGSANKEGSHKTHGAPLGADEIEATRKHLGWTYPAFEIPQEIYDAWNAKEQGAKLEADWNELFAQYQAKYPAEAA EFVRRMDKKLPDNFDEYVQAALKEVCAKAETIATRKASQNSIEILAKELPELVGGSADLTPSNLTDWSNSVSVTRDKGGN YIHYGVREFGMGAIMNGLVLHGGVKPFGATFLMFSEYERNALRMAALMKINPVFVFTHDSIGLGEDGPTHQPIEQTATLR LIPNMDVWRPCDTAESLVAWAEAVKAADHPSCLIFSRQNLKFQARSEQQLNDIKRGGYVISEAQGNAQAVIIATGSEVEL ALEAQKALAAQNIAVRVVSMPSTNVFDRQDAAYQAAVLPEGLPRIAVEAGHADGWYKYVGLNGAVVGINRFGESAPADLL FKAFGFTVDNVVDTVKSVL |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| tktA | AAO17218.1 | TktA | Not tested | tcd island | Protein | 0.0 | 64 |
| APECO1_2641 | YP_859417.1 | transketolase | Not tested | Not named | Protein | 0.0 | 61 |
