Gene Information

Name : lysS (ST2083)
Accession : NP_378073.1
Strain : Sulfolobus tokodaii 7
Genome accession: NC_003106
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 2086679 - 2088013 bp
Length : 1335 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTTTGACATTTCCACTGCTGGAAGAGTAGCAAACATAAGAAGACACGGGAAAATTTCATTTGTTGATATTTTCGATGA
AGGAGAAAAATTACAATTACAGCTAAGAGTAAACGAACTAGGCGAAAAATATGATAAATTTTTTGAGATTGTTGATAGAG
GTGATATAATTGGTGTAAAAGGAGATCTTCTATATACTATAAAGGGCGAATTAACACTTAGGATAAAAGATTATACAATG
CTTGCAAAATCATTAATAGAGCCTCCAGATTGGAGTAAACTGTCTCCAGAGTTTAGGTATGCTCATAGATATGTTGATTT
TCTGTATAACGATAATGCTAGGAAAGCTATGGAGATTAGGTTTTTAATAATTAGACTGATTAGAGAGTACCTCTATTCAA
AAGGATTCATAGAAGTTGAAACACCGATTTTACAGCCAGTTTATGGAGGTGCATTAGCAAAACCTTTTAAGAGTCACGTA
AACTATCTCGAGGAAGATTGGTATTTGAGAATTTCTCTCGAACTATATCTTAAGAGATTTATAGTAGGTGGTTTCAATAA
AGTTTTTGAAATAGGGAAAGTCTTTAGAAATGAGGATATTGATGTAACTCACAACCCTGAATTTACTCTAATGGAGTTAT
ACTGGGCTTATGCAGATTACAACGATATTATGAGATTAACAGAAGATATGCTACAATATGTGGTTAAAAGTATTTTTCAC
GATACTAAAATTAAGTATACCATAAGCGGTAAAGATTATGAAATAGACTTCTCACAATTTAAAAAAGTAACAATTTATGA
TGCTCTTTCAGAAGCTTTAGGCAAAAATGTTGAAAACGTAAGTGATGAGGAGTTAAAGAATTTGATGGATAAATATGGTC
TGAAACCTAGGGGTAACATGTATATTAGGGGTTTAATGATAGAGAAACTATTTGATAAATTAGTTGAGCCTAACTTAATA
CAACCAACGTTCATTTTAGATTATCCCATAGAGACTACACCATTATGTAAACCACATAGGAGTAAACCAGGTTTAGTTGA
AAGATTTGAGTTATTTATAGCTGGAATGGAGCTTGCAAATGCCTATACTGAGTTAAACGACCCTATTCTTCAAGACAAAT
TATTCAAACAGGAACAAGAGATGTTTAGAAGAGGGGATGAAGAGGCTCATCCTTATGATGTGGATTTTGTTAGAGCTTTA
AGCTATGGCATGCCTCCTACTGGAGGACTAGGTATTGGTATTGACAGACTTGTAATGTTGCTCACAAACAATTATAGTAT
AAAAGAAGTTATACCTTTCCCAATGCTTAGTAGTAAAATTATTGAAGAGGATTGA

Protein sequence :
MFDISTAGRVANIRRHGKISFVDIFDEGEKLQLQLRVNELGEKYDKFFEIVDRGDIIGVKGDLLYTIKGELTLRIKDYTM
LAKSLIEPPDWSKLSPEFRYAHRYVDFLYNDNARKAMEIRFLIIRLIREYLYSKGFIEVETPILQPVYGGALAKPFKSHV
NYLEEDWYLRISLELYLKRFIVGGFNKVFEIGKVFRNEDIDVTHNPEFTLMELYWAYADYNDIMRLTEDMLQYVVKSIFH
DTKIKYTISGKDYEIDFSQFKKVTIYDALSEALGKNVENVSDEELKNLMDKYGLKPRGNMYIRGLMIEKLFDKLVEPNLI
QPTFILDYPIETTPLCKPHRSKPGLVERFELFIAGMELANAYTELNDPILQDKLFKQEQEMFRRGDEEAHPYDVDFVRAL
SYGMPPTGGLGIGIDRLVMLLTNNYSIKEVIPFPMLSSKIIEED

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 1e-66 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS NP_378073.1 lysyl-tRNA synthetase VFG1668 Protein 7e-67 42