Gene Information

Name : smpB (RC0596)
Accession : NP_360233.1
Strain : Rickettsia conorii Malish 7
Genome accession: NC_003103
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 583132 - 583590 bp
Length : 459 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGACTGAATATAAGAAAGTTATTGCACAAAATAAGAAAGCCCTTTTTAATTATTTTATTGAAGAAAGATTAGAAGCGGG
TATTGTATTAAAGGGTAGTGAAGTACGGTCTCTGCGTCAGGGCAAAGCTTCTATAGAAGAAAGTCATGCGGCAGATACCA
GACATGAGGTATTTTTGTATAACTGCCATATTGCAGAATATGAAAAAGCGAATAGATTTAATCATGCTACTCGTAGACCG
CGTAAATTATTGTTGCATACTAAAGAGATAAAGAAAATTATCGGTAGAATTAGAATAAAAGGCTATACGCTAGTAGCTCT
TTCTATGTATTTTAATAAAAAAAATAAAGTGAAAGTTGAACTTGGTATTGCTAAAGGTAAGAAATTACATGATAAAAGAG
AGTCAATTAAAGAAAAAGACTGGAAAAGAGATCAGAGCAGATTAATAAGACAGAAGTAA

Protein sequence :
MTEYKKVIAQNKKALFNYFIEERLEAGIVLKGSEVRSLRQGKASIEESHAADTRHEVFLYNCHIAEYEKANRFNHATRRP
RKLLLHTKEIKKIIGRIRIKGYTLVALSMYFNKKNKVKVELGIAKGKKLHDKRESIKEKDWKRDQSRLIRQK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 3e-23 48
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 1e-19 47
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 3e-18 47