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Name : leuS (RC0585) Accession : NP_360222.1 Strain : Rickettsia conorii Malish 7 Genome accession: NC_003103 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 572865 - 575372 bp Length : 2508 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGAACCAAATAGAACAAAAATGGCAGTACATTTGGCAAGAAGAAAAAGCTTTTGAGGTATCAAACGCGAGTAGCAAGCC AAAATATTACGTACTTGAAATGCTGCCTTATCCTTCCGGTAAAATCCATGTAGGTCACGTACGCAACTATTCTATAGGTG ATGTTATTGCAAGGTTTATGACTATGCAAGGTTTTAATGTGCTTCATCCGATGGGCTGGGATGCTTTCGGGCTACCTGCC GAAAATGCCGCAATAAAAAATAATTCTCACCCAAAAAAATGGACATATTCTAATATCAAGAATATGAAAAAGCAGCTAAA ATCTATGGGCTTTTCTTATGATTGGTCTAGAGAGATAAATAGTTGCGATCCTGAGTATTATAAACATGAGCAGAAATTCT TTTTAGAGCTTTATGAACGAAATCTTGCTTATCAAAAAGAATCATTTGTTAATTGGGATCCGGTTGATAATACTGTGCTT GCAAATGAACAAGTTGTAGACGGGCGTGGTTGGCGTTCAGGTGCAATAGTTGTAAAACGTTATTTAAAGCAATGGTTCTT AAAAATTACCGATTATGCTGAAGAATTATTAAACGAAATTCAGAATTTAAAAGAGTGGCCTGAAGCTGTTCGGTCTATGC AAGAGAAATGGATAGGTAAATCGATAGGTGCTAATTTTCATTTCAAAATTAAGGATAATGAAGAGACTACTATAGAAGTA TTCTCAACCAAACCTGAAACCATTTTTGGTGCTAGCTTTATAGGAATTGCCTTTAATCATCCGATAATAGAGCGGTTAGT TTCTAAAACACCTGAAATACTCGCTTTTATAACTCAATGCTCGCATATTACAAGAAGTAGCGAACTAGAAAAGGCTGAAA AGGAAGGTGTATTTACCGGTCTTTTTGTTACTCATCCTTTTGATTCAAATATAGTTTTACCGGTTATTATTACTAATTTT GTGCTAATGGATTATGGAACTGGTGCAATATTTGGTTGCCCTGCTCATGACGAATGTGACCATGAATTAGCTGTCAAAAT GAATTTATCTATTAAACAAGTAATTAAAGCAGATATGGATGTACAAAAGACCGCTTATACGGAAGATGGAATTTTAATTA ATTCGGATTTTCTAAACGGCTTAACTAGTAACGAAGCAAAACAAGAAGTCATCGGAGAATTTGAGAAACTAGGCATAGGT AAACGCAGCGTAAATTATCGTCTAAAAGATTGGGGGATTTCAAGGCAGCGCTTTTGGGGATGTCCTATTCCTATGATTCA CTGCGAAATTTGTGGCATAGTGCCTGTACCTTACAAAGACTTACCCGTTACTTTACCTGATGATGTCAATTTTGACGGTC ACGGTAATCCGCTTGATCATCATCCTAGTTGGAAACATGTTAATTGTCCGAAATGCGATAAGCCGGCTGTGCGTGAAACC GATACTTTTGATACATTTTTTGAATCATCTTGGTATTTTACGAGATATTGCAATAGCAATGCTACAGAGATGACTGATAA AAAAGCTTGTGATTACTGGTTACCGGTCGATAAATATATAGGCGGCATTGAACATGCGGTAATGCATTTATTATATGCAA GGTTTTTCACAAAAGTAATGAACGAACAGAATTACGTAAGCGTTCGAGAGCCTTTTAAAGGGCTATTTACTCAAGGTATG GTGCTGCATGCCACTTACAAAGATGAACATAATAATTGGTTGTATCCTGAAGAAGTAGTTAAAAAGGGTAATGAATTTTT TCATAAAGAAAGCAATAATAGAGTAGTGCAGGGACGCATTGAAAAGATGAGTAAGTCTAAAAAGAATCTCATCGATCTTG AGACAATGCAAGAGCAATATGGGGCAGATGCTATTAGGCTTTTTGTACTGTCCGATAGTCCGCCTGAGAAAGATCTAGAA TGGTCGGCAAGCGGTATTGAAGGCTGCTCACGTTTTATTAATAAGCTTGAGTATATGTTTAAGGCGATAGATTCTTTAAA AGATGATGTGAATAGCGAGGTTAATAAAGAGCTTAATAGGTTAGTACATTTTACAATAAAGCACGTCGCCGAAGATATAA AGCATTTTGCCCTAAACAGAGCAATAGCACGTATGCGCGAGCTTTCTAATGCTATATCTGCTGAAATATCCAAAGATAAA ATTGATGTTAAAACCGTAAGGCATGGCTTTAATGTTTTAGTACAGCTACTAAATCCTTTTATCCCGCATATTACAGAAGA AATTTGGCAAAAGCTTGGCAATAAAGAGCGATTATATAATTTGTCTTTTCCTGCATTTGATGAATCAATGCTAGAGTTAG ATACATATATTATGGCAGTGCAGGTTAACGGCAAACTCCGTGATACCTATGAGTTTAAAACTTCCGTAAGTGAAGATGAA ATAAAGCAAGTTACCGTCAGTCTGCCAAAGGTACAAAAGTTCTTAGAAGGGAAAGAGCCGAAGAAGATTATCCTCGTTCC TCGTAAAATTGTGAATATACTCGTTTAA Protein sequence : MNQIEQKWQYIWQEEKAFEVSNASSKPKYYVLEMLPYPSGKIHVGHVRNYSIGDVIARFMTMQGFNVLHPMGWDAFGLPA ENAAIKNNSHPKKWTYSNIKNMKKQLKSMGFSYDWSREINSCDPEYYKHEQKFFLELYERNLAYQKESFVNWDPVDNTVL ANEQVVDGRGWRSGAIVVKRYLKQWFLKITDYAEELLNEIQNLKEWPEAVRSMQEKWIGKSIGANFHFKIKDNEETTIEV FSTKPETIFGASFIGIAFNHPIIERLVSKTPEILAFITQCSHITRSSELEKAEKEGVFTGLFVTHPFDSNIVLPVIITNF VLMDYGTGAIFGCPAHDECDHELAVKMNLSIKQVIKADMDVQKTAYTEDGILINSDFLNGLTSNEAKQEVIGEFEKLGIG KRSVNYRLKDWGISRQRFWGCPIPMIHCEICGIVPVPYKDLPVTLPDDVNFDGHGNPLDHHPSWKHVNCPKCDKPAVRET DTFDTFFESSWYFTRYCNSNATEMTDKKACDYWLPVDKYIGGIEHAVMHLLYARFFTKVMNEQNYVSVREPFKGLFTQGM VLHATYKDEHNNWLYPEEVVKKGNEFFHKESNNRVVQGRIEKMSKSKKNLIDLETMQEQYGADAIRLFVLSDSPPEKDLE WSASGIEGCSRFINKLEYMFKAIDSLKDDVNSEVNKELNRLVHFTIKHVAEDIKHFALNRAIARMRELSNAISAEISKDK IDVKTVRHGFNVLVQLLNPFIPHITEEIWQKLGNKERLYNLSFPAFDESMLELDTYIMAVQVNGKLRDTYEFKTSVSEDE IKQVTVSLPKVQKFLEGKEPKKIILVPRKIVNILV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 1e-152 | 41 |
