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Name : pykF (spr0797) Accession : NP_358391.1 Strain : Streptococcus pneumoniae R6 Genome accession: NC_003098 Putative virulence/resistance : Virulence Product : pyruvate kinase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0469 EC number : 2.7.1.40 Position : 800243 - 801748 bp Length : 1506 bp Strand : + Note : catalyzes the formation of phosphoenolpyruvate from pyruvate DNA sequence : ATGAACAAACGTGTAAAAATCGTTGCAACTTTGGGTCCTGCGGTAGAAATCCGTGGTGGTAAAAAATTCGGTGAGGACGG ATACTGGGGTGAAAAACTTGATGTTGAAGCTTCAGCTAAAAACATTGCTAAATTGATTGAAGCTGGTGCTAACACATTCC GATTCAACTTCTCACACGGCGACCACCAAGAACAAGGTGAGCGTATGGCAACTGTTAAACTTGCGGAAAAAATTGCAGGT AAAAAAGTTGGTTTCCTTCTTGATACAAAAGGACCTGAAATCCGTACAGAATTGTTCGAAGGTGAAGCTAAAGAATATTC ATACAAAACTGGTGAAAAAATTCGTGTTGCAACTAAACAAGGAATCAAATCAACTCGTGAAGTGATTGCGTTGAACGTTG CTGGTGCTCTTGATATCTATGATGATGTTGAAGTTGGTCGTCAAGTTTTGGTTGACGATGGTAAACTTGGTCTTCGTGTG GTTGCTAAAGATGATGCAACTCGTGAATTTGAAGTTGAAGTTGAAAACGATGGTATCATCGCTAAACAAAAAGGTGTGAA CATCCCTAACACTAAAATTCCTTTCCCAGCTCTTGCTGAACGCGATAACGACGATATCCGTTTCGGTCTTGAACAAGGTA TCAACTTCATCGCAATTTCATTCGTACGTACTGCAAAAGATGTGAACGAAGTTCGTGCAATCTGTGAAGAAACTGGAAAC GGACATGTTCAATTGTTCGCTAAAATCGAAAACCAACAAGGTATCGATAACTTAGACGAAATCATCGAAGCAGCTGATGG TATTATGATTGCTCGTGGTGATATGGGTATCGAAGTACCGTTCGAAATGGTTCCAGTTTATCAAAAAATGATTATCAAGA AAGTCAATGCTGCAGGTAAAGTTGTTATCACTGCAACAAACATGCTTGAAACAATGACTGAAAAACCACGTGCAACTCGT TCAGAAGTATCAGACGTATTCAACGCTGTTATCGACGGAACTGACGCTACAATGCTGTCAGGCGAGTCTGCAAACGGTAA ATACCCACTCGAGTCAGTAACTACAATGGCTACAATCGACAAGAACGCTCAAGCTCTTCTTAATGAATACGGACGTCTTG ATTCAGATTCATTTGAGCGTAACTCTAAGACAGAAGTAATGGCTTCTGCTGTTAAAGATGCTACTAGCTCAATGGATATC AAATTGGTTGTAACTCTTACTAAGACAGGTCATACTGCACGTTTGATTTCTAAATACCGTCCAAATGCTGACATCTTAGC ATTGACATTTGACGAATTGACAGAACGTGGCTTGATGTTGAACTGGGGTGTTATCCCAATGTTGACAGATGCTCCATCTT CAACTGACGATATGTTCGAAATCGCTGAACGTAAAGCGGTAGAAGCAGGTCTCGTTGAGTCAGGCGATGATATCGTTATC GTTGCTGGTGTGCCAGTAGGAGAAGCTGTTCGCACAAACACAATGCGTATCCGCACAGTACGTTAA Protein sequence : MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAKLIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAG KKVGFLLDTKGPEIRTELFEGEAKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIAISFVRTAKDVNEVRAICEETGN GHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMGIEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATR SEVSDVFNAVIDGTDATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVKDATSSMDI KLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTDAPSSTDDMFEIAERKAVEAGLVESGDDIVI VAGVPVGEAVRTNTMRIRTVR |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| STY1744 | NP_456147.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 3e-80 | 45 |
| pykF | YP_216386.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 1e-80 | 45 |
| pykF | NP_805051.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 1e-80 | 45 |
| pykF | CAA68205.1 | pyruvate kinase like protein | Not tested | SPI-2 | Protein | 8e-81 | 45 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| pykF | NP_358391.1 | pyruvate kinase | VFG0479 | Protein | 6e-81 | 45 |
