Gene Information

Name : pdp (spr0744)
Accession : NP_358338.1
Strain : Streptococcus pneumoniae R6
Genome accession: NC_003098
Putative virulence/resistance : Unknown
Product : pyrimidine-nucleoside phosphorylase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0213
EC number : 2.4.2.2
Position : 740471 - 741748 bp
Length : 1278 bp
Strand : +
Note : Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway

DNA sequence :
ATGAGAGCAGTTGATTTAATACAAAAAAAACGAGACGGTCAAGAACTGACTTCAAGTGAAATTGAATGGCTGGTAGAAGG
CTATGTGTCAGGAACTGTTCCTGATTATCAGATGTCTGCCTTTGCTATGGCTGTTTATTTTAAAGGAATGACGACTCGAG
AAATCTCTGATTTAACGATGAATATGGTTAAGACTGGGCAAGAGTTTGACCTGTCAGCCATTGATGGTGTGAAAGTTAAC
AAGCATTCTACTGGTGGTGTCGGCGATAAGGTAACCTTGATTTTAGTTCCTCTTGTTGCTAGCTTCGGTGTGCCTGTAGC
AAAAATGAGTGGTCGTGGTCTTGGCCATACAGGCGGAACAATTGATAAATTGGAGTCCATTAAGGGCTATCAAGTAGAAC
GTAGTCAAGAGGATTTTATTCGTCAGGTTCAGGATATTGGAGTATCTGTCATTGGGCAATCAGACCAGCTGGTCAAAGCA
GATAAGCTTCTCTATGCCCTTCGTGATGTGACCGCAACTGTCGACACGATTCCTTTGATTGCGAGTTCGGTGATGAGCAA
GAAAATTGCGGCAGGGGCGGATGCTATTTTGCTAGACGTGACTGTCGGTGAGGGTGCCTTCATGAAGACGGTTGATGAGG
CGCGTGAGTTGGCTCAAACTATGGTAGATCTTGGTAAGGTTGTTGGACGGAAGACAGTAGCAGTGATTACGGATATGAGC
CAGCCTTTGGGACGAGCGATTGGAAATCGTCTGGAAATCCTTGAAGCATTGGAGATTTTGCAAGGTCAAGGACGTCAGGA
TATTACCCACTTTATTTGTGAATTGGCTCAAATTATGCTTGGTTTGGCAAATGTTAACAAAACTGTTGAAGAAGTTCGCC
AACATCTTGAGAATGGTCAAGCACTGGCTAAGTTTGAGGAAATGGTGCAAGCCCAAGGTGGAGACTTGGAAGACCTCTAT
CGTCCTGTAAATGTAGCTCATGTGGTGGAAATCCCTGCTCAGGAAACGGGTGTCATTTCAGCTCTTCCAGCTATGGACTT
TGGTCTTTATGCCATGAGGCTGGGTGCTGGTCGTGCAGTTAAGTCTGATGCCTTGGACTATGAAACAGGAATTGTTTTTG
AAAAGAAGATTGGAGACTCCGTTCAAAAGGGTGAAATTGTTGCAAAAGTATACACAAATGAAAAAATTCCACCTCAACTA
GTTACAGATTTCCAAAAATGTGTTAAAATAAGTGATGAAGTAAAAAAAATCCGTGAAATTGTAGAAATCATCTCCTAA

Protein sequence :
MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMAVYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVN
KHSTGGVGDKVTLILVPLVASFGVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELAQTMVDLGKVVGRKTVAVITDMS
QPLGRAIGNRLEILEALEILQGQGRQDITHFICELAQIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLY
RPVNVAHVVEIPAQETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYTNEKIPPQL
VTDFQKCVKISDEVKKIREIVEIIS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
deoA YP_005163381.1 Thymidine phosphorylase Not tested Not named Protein 9e-87 49