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Name : tktA (spr1841) Accession : NP_359433.1 Strain : Streptococcus pneumoniae R6 Genome accession: NC_003098 Putative virulence/resistance : Unknown Product : transketolase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0021 EC number : 2.2.1.1 Position : 1815951 - 1817927 bp Length : 1977 bp Strand : - Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo DNA sequence : ATGTCAAATCTATCTGTTAATGCAATTCGTTTTCTAGGTATTGACGCCATTAATAAAGCCAACTCAGGTCATCCAGGTGT GGTTATGGGAGCGGCTCCGATGGCTTACAGCCTCTTTACAAAACAACTTCATATCAATCCAGCTCAACCAAACTGGATTA ACCGCGACCGCTTTATTCTTTCAGCAGGTCATGGTTCAATGCTCCTTTATGCTCTTCTTCACCTTTCTGGTTTTGAAGAT GTCAGCATGGATGAGATTAAGAGTTTCCGTCAATGGGGTTCAAAAACACCAGGTCACCCAGAATTTGGTCATACGGCAGG GATTGATGCTACGACAGGTCCTCTAGGGCAAGGGATTTCAACTGCTACTGGTTTTGCCCAAGCAGAACGTTTCTTGGCAG CCAAATATAACCGTGAAGGCTACAATATCTTTGACCACTATACTTACGTTATCTGTGGAGACGGAGACTTGATGGAAGGT GTCTCAAGCGAGGCAGCTTCATACGCAGGTTTGCAAAAACTTGATAAGTTGGTTGTTCTTTATGATTCAAATGATATCAA CTTGGATGGTGAGACAAAGGATTCCTTTACAGAAAGTGTTCGTGACCGTTACAATGCCTACGGTTGGCATACTGCCTTGG TTGAAAATGGAACAGACTTGGAAGCCATCCATGCTGCTATCGAAACAGCAAAAGCTTCAGGCAAGCCATCTTTAATTGAA GTGAAGACGGTTATTGGATACGGTTCTCCAAACAAACAAGGAACTAATGCTGTACACGGCGCCCCTCTTGGAGCAGATGA AACTGCATCAACTCGCCAAGCCCTCGGTTGGGACTACGAACCATTTGAAATTCCAGAACAAGTATATGCTGATTTCAAAG AACATGTTGCAGACCGTGGCGCATCAGCTTATCAAGCTTGGACTAAATTAGTTGCAGATTATAAAGAAGCTCATCCAGAA CTGGCTGCAGAAGTAGAAGCCATCATCGACGGACGTGATCCAGTCGAAGTGACTCCAGCAGACTTCCCAGCTTTAGAAAA TGGTTTTTCTCAAGCAACTCGTAATTCAAGTCAAGATGCCTTGAATGTTGTGGCAGCTAAATTACCAACCTTCCTAGGTG GATCAGCTGACCTTGCTCACTCAAACATGACTTATATCAAGACAGATGGACTTCAAGACGATGCCAATCGCTTGAATCGT AACATTCAGTTTGGTGTTCGTGAATTTGCAATGGGAACAATCTTGAACGGGATGGCCCTTCATGGTGGACTTCGTGTATA CGGTGGAACTTTCTTCGTCTTCTCTGACTATGTGAAGGCAGCTGTCCGCTTGTCAGCCTTACAAGGACTTCCTGTGACTT ATGTCTTTACCCATGATTCAATCGCAGTTGGGGAAGATGGTCCGACTCACGAACCAGTTGAGCATTTAGCAGGTCTTCGT GCTATGCCAAATCTAAATGTTTTCCGTCCAGCAGATGCGCGTGAAACGCAAGCAGCTTGGTACCTTGCAGTGACAAGTGA GAAAACACCAACTGCCCTTGTCTTGACACGTCAAAACTTGACTGTTGAAGATGGAACAGACTTCGACAAGGTTGCTAAAG GTGCTTATGTTGTATATGAAAATGCAGCCGACTTTGATACCATCTTGATTGCGACAGGTTCAGAGGTTAATCTTGCTGTC TCAGCTGCTAAAGAATTGGCTAGTCAAGGCGAAAAAATCCGCGTAGTCAGCATGCCATCTACAGATGTCTTTGATAAACA AGATGCAGCTTACAAGGAAGAGATTCTTCCAAATGCAGTCCGCCGTCGTGTTGCAGTCGAAATGGGTGCAAGTCAAAACT GGTACAAATATGTTGGTCTCGATGGTGCCGTTCTAGGTATTGATACCTTCGGAGCCTCTGCCCCAGCACCAAAAGTATTG GCAGAATATGGCTTTACTGTAGAAAATCTTGTAAAAATTGTTCGAAACTTGAAATAA Protein sequence : MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLHINPAQPNWINRDRFILSAGHGSMLLYALLHLSGFED VSMDEIKSFRQWGSKTPGHPEFGHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGTDLEAIHAAIETAKASGKPSLIE VKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALGWDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPE LAAEVEAIIDGRDPVEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQDDANRLNR NIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGLPVTYVFTHDSIAVGEDGPTHEPVEHLAGLR AMPNLNVFRPADARETQAAWYLAVTSEKTPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAV SAAKELASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAVLGIDTFGASAPAPKVL AEYGFTVENLVKIVRNLK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| tktA | AAO17218.1 | TktA | Not tested | tcd island | Protein | 1e-154 | 50 |
| APECO1_2641 | YP_859417.1 | transketolase | Not tested | Not named | Protein | 1e-147 | 48 |
