Gene Information

Name : nadC (spr1829)
Accession : NP_359421.1
Strain : Streptococcus pneumoniae R6
Genome accession: NC_003098
Putative virulence/resistance : Unknown
Product : nicotinate-nucleotide pyrophosphorylase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0157
EC number : 2.4.2.19
Position : 1803124 - 1804023 bp
Length : 900 bp
Strand : -
Note : catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide

DNA sequence :
GTGATATTAAAAATAGAGGACTTAGTGATGTCAATCATTTCAACTGATTTAACCCCTTTTCAAATAGATGATACATTGAA
AGCAGCCTTGCGAGAAGATGTTCATTCCGAAGATTACAGTACCAATGCCATTTTTGATCATCATGGCCAAGCCAAGGTGT
CGCTTTTTGCCAAGGAAGCTGGTGTTTTAGCGGGACTAACCGTTTTTCAAAGGGTTTTTACCCTATTTGATGCCGAGGTG
ACCTTCCAGAATCCTCATCAATTTAAGGATGGGGATCGTTTGACTAGTGGCGATTTGGTTTTAGAAATCATAGGCTCGGT
GAGAAGTCTCTTAACATGTGAACGCGTTGCCTTGAATTTTTTACAACATTTATCAGGGATTGCTTCGATGACAGCTGCTT
ATGTAGAAGCCTTAGGCGATGATTGCATTAAGGTATTTGATACTCGAAAAACTACTCCTAATTTACGTCTTTTTGAGAAA
TATGCCGTGAGAGTTGGCGGTGGCTATAATCATCGCTTTAATTTATCAGATGCTATCATGCTAAAAGACAATCACATTGC
GGCAGTAGGTAGTGTTCAAAAGGCAATTGCTCAAGCGCGTGCCTATGCCCCTTTTGTGAAAATGGTCGAGGTGGAAGTGG
AAAGCCTTGCTGCTGCCGAAGAAGCTGCGGCGGCGGGTGCTGATATTATCATGTTGGATAATATGTCATTGGAACAGATT
GAACAGGCCATTACCCTAATTGCAGGACGTTCTCGGATTGAATGTTCTGGAAATATTGATATGACCACTATTAGCCGTTT
TCGTGGTTTAGCGATTGATTACGTCTCCAGTGGTAGTTTAACCCATAGTGCTAAGAGTCTTGATTTTTCCATGAAGGGGT
TAACCTACCTTGATGTCTAA

Protein sequence :
MILKIEDLVMSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKVSLFAKEAGVLAGLTVFQRVFTLFDAEV
TFQNPHQFKDGDRLTSGDLVLEIIGSVRSLLTCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEK
YAVRVGGGYNHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGADIIMLDNMSLEQI
EQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAKSLDFSMKGLTYLDV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nadC YP_281534.1 nicotinate-nucleotide pyrophosphorylase Not tested Not named Protein 2e-121 99