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Name : secA (spr1544) Accession : NP_359137.1 Strain : Streptococcus pneumoniae R6 Genome accession: NC_003098 Putative virulence/resistance : Unknown Product : preprotein translocase subunit SecA Function : - COG functional category : U : Intracellular trafficking, secretion and vesicular transport COG ID : COG0653 EC number : - Position : 1526391 - 1528904 bp Length : 2514 bp Strand : - Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap DNA sequence : ATGGCTAATATTTTAAAAACAATTATCGAAAATGATAAAGGAGAAATCCGTCGTCTGGAAAAGATGGCTGACAAGGTTTT CAAATACGAAGACCAAATGGCTGCTTTGACTGACGACCAACTAAAAGCAAAAACAGTTGAATTTAAGGAACGTTATCAAA ATGGAGAATCACTGGATTCATTGCTTTACGAAGCATTTGCGGTTGTCCGTGAAGGTGCCAAACGTGTCCTAGGTCTCTTC CCTTATAAGGTTCAGGTCATGGGGGGGATTGTTCTTCACCATGGTGACGTGCCAGAGATGCGTACAGGGGAAGGGAAAAC CTTGACTGCGACCATGCCGGTATACCTCAATGCCCTTTCAGGTAAAGGGGTTCACGTAGTTACGGTTAATGAATACCTGT CAGAACGTGACGCGACTGAGATGGGTGAATTGTACTCTTGGCTTGGTTTGTCAGTAGGGATTAACTTGGCTACCAAATCT CCAATGGAGAAAAAAGAAGCCTATGAGTGTGATATTACTTACTCAACTAACTCAGAAATCGGATTTGACTACCTTCGTGA CAATATGGTCGTTCGCGCTGAAAATATGGTACAACGTCCGCTTAACTATGCCTTGGTCGATGAGGTTGACTCTATCTTGA TTGACGAGGCTCGTACACCTTTGATTGTATCAGGTGCCAATGCGGTTGAAACCAGTCAGTTGTATCACATGGCAGACCAC TATGTAAAATCTTTGAACAAAGATGACTACATCATCGATGTGCAGTCTAAGACTATTGGTTTGTCTGATTCAGGGATTGA CAGGGCTGAAAGCTACTTCAAACTTGAAAACCTCTATGACATCGAAAACGTGGCTTTGACTCACTTTATCGATAACGCCC TTCGTGCCAACTACATCATGCTTCTCGATATTGACTATGTGGTGAGCGAAGAGCAAGAAATCTTGATTGTCGACCAATTT ACAGGTCGTACCATGGAAGGTCGTCGTTATTCTGATGGATTGCACCAAGCTATTGAAGCCAAAGAAGGTGTGCCAATCCA GGATGAAACCAAGACATCTGCCTCAATCACGTACCAAAACCTTTTCCGTATGTACAAAAAATTGTCTGGTATGACGGGTA CAGGTAAGACTGAGGAAGAAGAATTTCGTGAAATCTACAACATTCGTGTTATTCCAATCCCAACAAACCGTCCTGTTCAA CGTATTGACCACTCAGACCTTCTTTATGCAAGTATCGAATCTAAGTTTAAAGCGGTTGTCGAAGACGTTAAGGCTCGTTA CCAAAAGGGTCAACCTGTCTTGGTTGGTACAGTAGCGGTTGAAACTAGTGACTACATTTCTAAGAAATTGGTTGCAGCTG GTGTTCCTCACGAAGTCTTGAATGCCAAAAACCACTATAGAGAAGCCCAAATCATCATGAATGCTGGTCAACGTGGTGCC GTTACCATCGCAACCAACATGGCGGGTCGTGGTACCGACATCAAGCTTGGTGAAGGTGTTCGTGAACTTGGAGGACTTTG TGTTATTGGTACAGAACGTCATGAAAGTCGTCGTATCGATAACCAGCTTCGTGGACGTTCAGGTCGTCAAGGAGATCCAG GTGAGTCACAATTCTACCTATCTCTTGAAGATGATTTGATGAAACGTTTTGGTTCTGAACGCTTGAAGGGAATCTTTGAA CGTCTCAACATGTCTGAAGAGGCCATTGAGTCTCGCATGTTGACGCGTCAGGTTGAAGCAGCTCAGAAACGTGTCGAAGG AAATAACCACGATACCCGTAAACAAGTCCTTCAATACGATGATGTCATGCGTGAACAACGTGAGATTATCTATGCTCAAC GTTACGATGTCATCACTGCAGATCGTGACTTGGCACCTGAAATTCAGGCTATGATCAAACGCACGATTGAACGTGTCGTT GATGGTCATGCGCGTGCCAAACAAGATGAAAAACTAGAGGCAATTTTGAACTTTGCTAAGTATAACTTGCTTCCAGAAGA TTCTATTACGATGGAAGACTTGTCAGGCTTGTCTGATAAGGCCATCAAGGAAGAGCTTTTCCAACGTGCCTTGAAGGTTT ACGATAGTCAGGTTTCAAAACTACGCGATGAAGAAGCAGTTAAAGAATTCCAAAAAGTTTTGATTCTACGAGTGGTGGAT AACAAGTGGACAGATCATATCGATGCCCTTGATCAATTGCGTAACGCGGTTGGACTTCGTGGCTATGCTCAGAACAACCC TGTTGTTGAGTATCAGGCAGAAGGTTTCCGTATGTTTAATGATATGATTGGTTCGATTGAGTTTGATGTGACACGCTTGA TGATGAAAGCACAAATTCATGAACAAGAAAGACCACAGGCAGAACGTCATATCAGTACAACAGCGACTCGCAATATCGCT GCTCACCAAGCAAGTATGCCAGAAGATTTGGATTTGAACCAGATTGGACGCAATGAACTTTGCCCATGTGGTTCTGGTAA GAAATTTAAAAACTGTCACGGTAAAAGACAATAA Protein sequence : MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAKTVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLF PYKVQVMGGIVLHHGDVPEMRTGEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEARTPLIVSGANAVETSQLYHMADH YVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLENLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQF TGRTMEGRRYSDGLHQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIPIPTNRPVQ RIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKLVAAGVPHEVLNAKNHYREAQIIMNAGQRGA VTIATNMAGRGTDIKLGEGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFE RLNMSEEAIESRMLTRQVEAAQKRVEGNNHDTRKQVLQYDDVMREQREIIYAQRYDVITADRDLAPEIQAMIKRTIERVV DGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAIKEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVD NKWTDHIDALDQLRNAVGLRGYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRNIA AHQASMPEDLDLNQIGRNELCPCGSGKKFKNCHGKRQ |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| secA2 | YP_006310687.1 | preprotein translocase subunit SecA2 | Not tested | FWisland_3 | Protein | 3e-141 | 42 |
