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Name : nrdF (spr1066) Accession : NP_358660.1 Strain : Streptococcus pneumoniae R6 Genome accession: NC_003098 Putative virulence/resistance : Unknown Product : ribonucleotide-diphosphate reductase subunit beta Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0208 EC number : 1.17.4.1 Position : 1064634 - 1065596 bp Length : 963 bp Strand : + Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE DNA sequence : ATGGAAACTTACTACAAAGCCATTAACTGGAATGCCATCGAAGATGTCATCGACAAATCAACTTGGGAAAAACTGACGGA GCAATTTTGGCTCGATACACGTATTCCCTTATCAAACGACTTGGATGACTGGAGAAAGCTATCTAACAAAGAGAAAGACT TGGTCGGAAAAGTTTTTGGTGGTTTAACCCTTCTTGACACTATGCAATCTGAAACTGGGGTTCAAGCCCTTCGCGCAGAC ATCCGTACACCACATGAGGAAGCTGTTTTCAATAACATCCAATTTATGGAATCTGTCCACGCTAAATCTTACTCATCAAT CTTTTCTACCTTGAATACTAAGGCTGAGATTGAAGAAATTTTCGAATGGACCAATACCAATCCTTACCTACAAAAGAAGG CTGAGATTGTCAACGAAATCTACCTAAACGGCAGCCCACTTGAAAAGAAAGTTGCCAGCGTCTTCCTCGAAACCTTCCTC TTCTACTCTGGTTTCTTCACTCCCCTCTACTATCTCGGTAACAACAAACTAGCCAACGTTGCAGAAATCATTAAATTGAT TATTCGTGACGAGTCTGTTCACGGAACCTACATTGGTTACAAATTCCAACTTGGTTTCAATGAATTGCCTGAAGAAGAGC AAGAAAAACTCAAAGAATGGATGTACGACCTACTCTATACTCTTTATGAAAATGAAGAAGGCTACACAGAGAGTCTTTAT GACGGTGTTGGTTGGACTGAAGAGGTTAAAACCTTCCTTCGCTACAATGCCAATAAAGCTCTCATGAACATGGGACAAGA TCCACTTTTCCCAGATTCAGCTGAAGATGTCAACCCAATCGTTATGAACGGTATTTCAACAGGAACTTCCAACCATGACT TCTTCTCTCAAGTCGGAAATGGTTACCTTCTTGGCGAAGTTGAAGCCATGCAAGACGATGACTATAACTACGGTTTAGAC TAA Protein sequence : METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDWRKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRAD IRTPHEEAVFNNIQFMESVHAKSYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLKEWMYDLLYTLYENEEGYTESLY DGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAEDVNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| cur_1479 | YP_001800873.1 | ribonucleoside-diphosphate reductase subunit beta | Not tested | Not named | Protein | 8e-72 | 50 |
