Gene Information

Name : tktA (Atu3736)
Accession : NP_356885.1
Strain :
Genome accession: NC_003063
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 815073 - 817055 bp
Length : 1983 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGATTTCTCGCGACAAACACAACCGGATGGCCAATGCGATCCGCTTTCTTGCCATGGATGCAGTGGAGAAGGCCAACTC
CGGCCATCCCGGACTGCCGATGGGCGCCGCCGATGTCGCCACCGTTCTTTTCACCCGCTACCTGAAATTCGATCCGAAGG
CGCCTCTGTGGGCGGACCGCGACCGCTTCGTGCTGTCTGCCGGCCATGGCTCCATGCTGCTTTACTCGCTGCTTTATTTG
ACGGGCTACGAGGACATGACGATCGACGAGATCAAGCGGTTCCGTCAGTTCGGCTCCAAGACCGCCGGCCATCCTGAATA
TGGCCATGCCACCGGCATCGAAACGACCACCGGTCCGCTCGGCCAGGGCATTGCCAACGCCGTCGGCATGGCAATTGCTG
AGCGCAAGCTGGAAGAGGAGTTCGGCTCCGACCTGCAGAGCCACTTCACCTATGTGCTGTGCGGCGACGGCTGCCTCATG
GAAGGCATCAGCCACGAAGCCATCGCGCTTGCCGGCCATCTGAAGCTCAACAAGCTCGTTCTCTTCTGGGACGACAACAA
CATCACCATCGACGGTGAAGTTGGCCTGTCCGACAGCACCGACCAGATCGCCCGCTTCCAGGCCGTTCACTGGAACACTA
TCCGTGTTGATGGCCATGATCCCGACGCGATTGCTGCCGCCATCGAGGCAGCGCAGAAATCCGACCGCCCGACCTTCATC
GCCTGCAAGACCGTCATCGGTTTCGGCGCCCCCAACAAGCAGGGTACCCACAAGGTGCACGGCAACCCGCTCGGCGCAGA
AGAAATCGCCGCTGCCCGCAAGAGCCTGAACTGGGAAGCCGAAGCCTTCGTCATTCCGGAAGATGTGCTCGATGCATGGC
GCCTCGCCGGCCTGCGCTCCACCAAGACGCGCCAGGACTGGGAAGCCCGTCTCGAAGCCACCGAGACGGCCAAGAAGGCC
GAATTCAAGCGCCGCTTTGCCGGCGACCTGCCCGGCAACTTCGACAGCTCCATCGATGCCTTCAAGAAAAAGATCATCGA
GAACAACCCGACGGTTGCCACCCGCAAGGCCTCGGAAGATTCGCTCGAAGTCATCAACGGCATCCTGCCGGAAATGGTCG
GCGGTTCGGCTGACCTGACGCCGTCCAACAACACCAAGACCAGCCAGATGAAGTCGATCACGCCGACGGACTTCTCCGGC
CGTTACCTGCATTACGGCATCCGCGAGCACGGCATGGCTGCGGCCATGAACGGTATCGCTCTCCACGGCGGTCTCATCCC
CTATGCCGGTGGCTTCCTGATCTTCTCGGATTATTGCCGTCCGTCGATCCGCCTTGCAGCACTGATGGGCATCCGCGTCG
TCCACGTTCTGACGCACGATTCCATCGGCGTCGGTGAAGATGGTCCGACCCACCAGCCGGTCGAGCAGATCGCAGCGTTG
CGCGCCATTCCGAACCTGCTCGTCTTCCGCCCGGCGGATGAAACCGAGACGGCGGAATGCTGGCAGCTGGCTCTCGAGCA
AAAGCACCGTCCGTCCGCACTGGCGCTTACCCGCCAGAATCTCACGCCTTCGCGCAAGGAATATGAAGAGAAGAACCTGT
CCGCTTACGGCGCATACGAACTCGTCTCCGCCAGCGACGCCAAGGTTTCGATCTTCGCTTCCGGTTCGGAAGTCGAAGTG
GCGCTGAAAGCTGCTGCGACGCTGAAGGACAAGGGTGTTTCCGCCCGCGTCGTTTCCGTTCCCTGCTTCGAACTCTTCAA
GGAACAGCCGGAAACCTATCGCAACGCCATCATCGGCAAGGCTCCGGTCAAGATCGCGGTGGAAGCCGCCATCCGCCAGG
GCTGGGATTACTTCATCGGCAATGACGGCGCTTTCGTCGGCATGCACTCCTTTGGAGCCTCTGCACCGGCGAAGGATCTC
TTCAAGCACTTCGGCATCACGGCGGAAGCCGTCGTCGCCGCAGTCGAGGCAAAACTTGCATGA

Protein sequence :
MISRDKHNRMANAIRFLAMDAVEKANSGHPGLPMGAADVATVLFTRYLKFDPKAPLWADRDRFVLSAGHGSMLLYSLLYL
TGYEDMTIDEIKRFRQFGSKTAGHPEYGHATGIETTTGPLGQGIANAVGMAIAERKLEEEFGSDLQSHFTYVLCGDGCLM
EGISHEAIALAGHLKLNKLVLFWDDNNITIDGEVGLSDSTDQIARFQAVHWNTIRVDGHDPDAIAAAIEAAQKSDRPTFI
ACKTVIGFGAPNKQGTHKVHGNPLGAEEIAAARKSLNWEAEAFVIPEDVLDAWRLAGLRSTKTRQDWEARLEATETAKKA
EFKRRFAGDLPGNFDSSIDAFKKKIIENNPTVATRKASEDSLEVINGILPEMVGGSADLTPSNNTKTSQMKSITPTDFSG
RYLHYGIREHGMAAAMNGIALHGGLIPYAGGFLIFSDYCRPSIRLAALMGIRVVHVLTHDSIGVGEDGPTHQPVEQIAAL
RAIPNLLVFRPADETETAECWQLALEQKHRPSALALTRQNLTPSRKEYEEKNLSAYGAYELVSASDAKVSIFASGSEVEV
ALKAAATLKDKGVSARVVSVPCFELFKEQPETYRNAIIGKAPVKIAVEAAIRQGWDYFIGNDGAFVGMHSFGASAPAKDL
FKHFGITAEAVVAAVEAKLA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 7e-152 52
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 2e-145 49