Gene Information

Name : lpdA3 (SMc03204)
Accession : NP_387041.1
Strain : Sinorhizobium meliloti 1021
Genome accession: NC_003047
Putative virulence/resistance : Unknown
Product : dihydrolipoamide dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : 1.8.1.4
Position : 3168434 - 3169828 bp
Length : 1395 bp
Strand : +
Note : E3 component of the branched-chain alpha-keto acid dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide

DNA sequence :
ATGAAGGAAATCTCCTGCAAGCTCCTGGTTCTCGGCGCCGGACCCGGCGGCTATGTCGCGGCGATCCGCGCCGGCCAGCT
CGGCGTCAACACGGTGATCGTCGAGAAAGCGAAGGCGGGCGGCACCTGCCTGAATGTCGGCTGCATTCCGTCGAAGGCGC
TGATCCATGCGGCGGACGAATATCACAGGCTGCGCGCGGCTGCCTCGGGCAAGGGCCCGCTCGGCCTTTCCTTGAGTGCT
CCGGCGATCGACCTCAGGCGAACGATCGCCTGGAAGGACGGCATCGTCGGACGGCTGAACGGTGGGGTCACGGGGCTCCT
GAAGAAGGCGGGCGTCAAGGCGGTCATCGGCGAAGGGCGATTCGTAGACGGCAAGACGGTGGATGTAGAAACGGAAACCG
GGCTTCAGCGCATTCGGGCGGAAGCAATCGTAATCGCGACCGGTTCGGCGCCGGTCGAGCTTCCCGACCTCCCCTTCGGC
GGAAGCGTCATTTCCTCGACCCAAGCGCTGGCGCTGACGGACGTGCCGCAGACGCTCGCGGTCATCGGCGGCGGCTATAT
CGGTCTCGAACTCGGAACCGCCTTTGCCAAGCTTGGCTCCAAAGTCACCGTGCTCGAAGCGCTGGACCGGATCCTGCCGC
AATACGACGCCGATCTCTCGAAGCCGGTGATGAAGCGGCTCGGCGAACTCGGTGTGGAGGTCTTCACCCGCACCGCGGCC
AAACGGCTCTCCGCCGATCGGCGGGGCTTGCTTGCCGAGGAGAACGGCCGCGCCTTCGAGGTCCCGGCGGAGAAGGTCCT
CGTCACCGTCGGCCGCCGGCCCGTGACGGATGGCTGGGGGTTGGAGGAAATCGACCTCGACCACTCAGGCCGCTTCATCC
GCATCGACGACCAATGCCGCACCTCGATGCGCGGCGTCTATGCGATCGGCGACGTGACCGGCGAGCCGATGCTTGCGCAC
CGGGCGATGGCACAAGGCGAAATGGTCGCGGAAATCGTCGCCGGGCATAAGCGGAGCTGGGACAAGCGCTGCATTCCGGC
GGTCTGCTTCACCGACCCGGAAATCGTCGGCGCCGGCCTCTCGCCGGAAGAGGCGCGCGCCGCCGGCATCGACGTCAAGA
TCGGCCAATTTCCCTTCCAGGCAAACGGCCGCGCCATGACGACGCTCTCCGAGGACGGCTTCGTGCGGGTCATCGCCCGC
GCCGACAATCACCTGGTTCTCGGCATCCAGGCTGTCGGCCATGGCGTTTCGGAACTTTCGGCGACTTTTGCGCTGGCGAT
CGAGATGGGCGCGCGGCTGGAGGACATCGCCGGCACCATACATGCGCATCCGACCCAATCGGAAGCCTTCCAGGAGGCAG
CCCTCAAGACGTTGGGGCACGCTCTGCATATTTGA

Protein sequence :
MKEISCKLLVLGAGPGGYVAAIRAGQLGVNTVIVEKAKAGGTCLNVGCIPSKALIHAADEYHRLRAAASGKGPLGLSLSA
PAIDLRRTIAWKDGIVGRLNGGVTGLLKKAGVKAVIGEGRFVDGKTVDVETETGLQRIRAEAIVIATGSAPVELPDLPFG
GSVISSTQALALTDVPQTLAVIGGGYIGLELGTAFAKLGSKVTVLEALDRILPQYDADLSKPVMKRLGELGVEVFTRTAA
KRLSADRRGLLAEENGRAFEVPAEKVLVTVGRRPVTDGWGLEEIDLDHSGRFIRIDDQCRTSMRGVYAIGDVTGEPMLAH
RAMAQGEMVAEIVAGHKRSWDKRCIPAVCFTDPEIVGAGLSPEEARAAGIDVKIGQFPFQANGRAMTTLSEDGFVRVIAR
ADNHLVLGIQAVGHGVSELSATFALAIEMGARLEDIAGTIHAHPTQSEAFQEAALKTLGHALHI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0077 NP_763632.1 dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 Not tested SCCpbp4 Protein 3e-84 44