Gene Information

Name : kdsB (SMc02898)
Accession : NP_384329.1
Strain : Sinorhizobium meliloti 1021
Genome accession: NC_003047
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 255204 - 255956 bp
Length : 753 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAATCGTGAACAATCGGGCAAAACCCTCGTACTCATTCCGGCGCGCATGGCGTCGACGCGCCTTCCCGGCAAGCCGCT
TGCCGATATTTGCGGCCTGCCGATGATCGTGCAGGTGGCAAGGCGGGCGGCGGAAGCCGAGGTCGGGCGGATCGTGGTGG
CGGTCGATCATCCCGATGTCTTCGCGGCCGTGACCGGCGCCGGCTTCGAGGCGATCATGACGCGTGTCGATCACCAGTCC
GGCTCCGACCGGATTCACGAGGCGCTCCTGAAGGCCGATCCGCATGGCGAAGCGGAAATCGTCATCAACGTGCAGGGCGA
TCTTCCGACCATCGAGCCCGGTCCGATTCGTGCCGCGCTGAAGCCGCTGGAAAATCCCGCGACCGACATCGCCACACTGA
CCGTGGCGATCACCGACGAACACGAAAAGACCAATCCCAACGTCGTCAAGGTCGTCGGCTCCCCGCTTTCCGACAGCCGC
TTTCGCGCGCTCTATTTCACCCGCGCCACCGCGCCCTATGGCGAAGGGCCCCTCTATCACCACATCGGGCTTTATGCCTA
TCGTCGCAAGGCGCTGGAGACTTTCGTTTCGCTGAAGCCGTCGACGCTCGAGAAGCGCGAATCGCTGGAGCAATTGCGGG
CGCTCGAAGCGGGCATGCGCATCGATGTCGAGGTCGTGGACTCAGTGCCGCTCGGGGTCGACACGCCGGCCGATCTCGAC
AAGGCCCGCCGCATCCTTTCCGCCCGCGTCTGA

Protein sequence :
MNREQSGKTLVLIPARMASTRLPGKPLADICGLPMIVQVARRAAEAEVGRIVVAVDHPDVFAAVTGAGFEAIMTRVDHQS
GSDRIHEALLKADPHGEAEIVINVQGDLPTIEPGPIRAALKPLENPATDIATLTVAITDEHEKTNPNVVKVVGSPLSDSR
FRALYFTRATAPYGEGPLYHHIGLYAYRRKALETFVSLKPSTLEKRESLEQLRALEAGMRIDVEVVDSVPLGVDTPADLD
KARRILSARV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 9e-30 46
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 9e-29 45
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 7e-29 45