Gene Information

Name : thyA (SMc01444)
Accession : NP_386233.1
Strain : Sinorhizobium meliloti 1021
Genome accession: NC_003047
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 2288124 - 2288918 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGCGACAATATCTCGATCTCCTCGAACATGTGATCACAACGGGTACCGACCGGGGCGACCGTACGGGTACGGGCACGCG
CTCGGTGTTCGGCTACCAGATGCGCTTCGACCTGTCGCAGGGTTTCCCGGTGCTGACCACCAAGAAGCTGCATCTGCGTT
CGATCATTCACGAGCTTCTGTGGTTCCTCAGGGGCGACACGAACGTCGCCTATCTCAAGGACAACGGGGTGAGCATCTGG
GACGAATGGGCGGACGAAAACGGCGAGCTCGGACCGGTCTACGGCTACCAATGGCGCTCCTGGCCGACGCCCGATGGCCG
ACATATCGACCAGATCGCGGCGCTGGTCGAAGGCCTGAAGACCAATCCGAATTCCCGCCGCCACATCGTTTCGGCCTGGA
ACCCGGCGCTTGTGGACGAAATGGCGCTGCCGCCATGCCACTGTCTGTTCCAGTTCTACGTGGCGGACGGGAAGCTCTCC
TGCCAGCTCTACCAGCGCTCGGCCGATATCTTTCTCGGCGTACCCTTCAATATCGCTTCCTACGCTCTGCTGACGATGAT
GGTGGCGCAGGTGACTGGGCTCGAAGCCGGCGATTTCGTTCATACGCTTGGTGACGCGCATATCTACCGCAACCACTTCG
AGCAGGCGCAGCTGCAGCTGACGAGAACGCCGAAGCCGCTGCCCAAAATGGAAATAAATCCGGCGGTGAAGGATATATTT
TCGTTTAGATTCGAAGACTTTGAGCTCGTCGGCTACGAAGCCGATTCACATATCAAGGCGCCGGTCGCGGTCTAG

Protein sequence :
MRQYLDLLEHVITTGTDRGDRTGTGTRSVFGYQMRFDLSQGFPVLTTKKLHLRSIIHELLWFLRGDTNVAYLKDNGVSIW
DEWADENGELGPVYGYQWRSWPTPDGRHIDQIAALVEGLKTNPNSRRHIVSAWNPALVDEMALPPCHCLFQFYVADGKLS
CQLYQRSADIFLGVPFNIASYALLTMMVAQVTGLEAGDFVHTLGDAHIYRNHFEQAQLQLTRTPKPLPKMEINPAVKDIF
SFRFEDFELVGYEADSHIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 2e-76 65