Gene Information

Name : serS (SMc02064)
Accession : NP_385638.1
Strain : Sinorhizobium meliloti 1021
Genome accession: NC_003047
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1653130 - 1654413 bp
Length : 1284 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTCGATATCAAATGGATCCGTGAGAATGCAGACGCGCTCGATGAAGCCCTGGCGAAACGGGGTGCGGAGCCATTGTC
GGCGTCCCTGATCGCACTTGACGAACGCCGCCGCGCAGTCCTCCAGTCGTTGCAGGACATGCAGTCGCGGCGCAATGCTG
CGTCGAAGGAGATCGGCGCGGCGATGGCCCAGAAGAACAGCGAGCTGGCCGACAGGCTCAAGGCCGAAGTCGCCGACCTC
AAGAATGCGTTGCCGGCGGCCGAAGAGGAAAGCCGCCGGATCGAGGCCGAGCTCTCGGATGCGCTGTCGCGCATCCCCAA
CACGCCGCTCGCCGACGTGCCCGTCGGTGCGGACGAAAGCGCAAATGTCGTGACCCGGGTCGTCGGCGCCAAGCCCGGCT
GGAACCACAAGCCTCTCGAGCATTTCGAGATCGGCGAGGCGCTGGGACTGATGGACTTCGAAGGAGCGGCCCGGATTGCC
GGCTCGCGCTTCACCATCCTGAAGGGCCAGCTTGCACGCCTCGAGCGGGCACTCGGCCAGTTCATGCTTGATCTGCATAC
CGGGGAGCATGGCTACATCGAGGTTCAGCCTCCATTGCTCGTCCGCGACGATGCGATGTACGGCACCGGACAGTTGCCGA
AATTCTCCGACGATCTCTTCCGTACGACCGACGGGCGCTGGCTGATCCCGACCGCGGAAGTCCCGCTGACGAACATGGTG
CGGGAGCAGATTCTCGACGGTGAAAAACTACCGTTGCGCTTCACTGCGCTGACCCCGTGCTTCCGCTCCGAGGCCGGTTC
CGCAGGTCGTGACACCCGCGGCATGTTGCGCCAGCATCAGTTCAACAAGGTCGAACTGGTGTCGATCACCGACGCCGAAA
GTTCGATAGACGAGCACGAGCGGATGACCGCTTGTGCCGAGGAGGTGCTGAAGCGCCTCGGCCTGCACTACCGCGTCATG
ACGCTCTGCACCGGCGATATGGGGTTCGGCGCGCGCAAGACCTATGATCTCGAGGTCTGGCTGCCGGGCCAGGACGCCTA
TCGCGAAATTTCCTCCTGCTCCGTCTGCGGCGATTTCCAGGCCCGCCGGATGAACGCACGTTACCGCGGGAAAGAAGAGA
AGGGGACGAAGTTCGTCCACACGCTCAACGGATCCGGCGTCGCCCTCGGCCGGGCGCTGATTGCCGTGATCGAGAATTAC
CTGAATGATGACGGCTCGATCACGGTGCCGGACGTCCTTGTGCCCTATATGGGCGGCCTGCGGCGGATCGAGAAATCGGC
CTAA

Protein sequence :
MLDIKWIRENADALDEALAKRGAEPLSASLIALDERRRAVLQSLQDMQSRRNAASKEIGAAMAQKNSELADRLKAEVADL
KNALPAAEEESRRIEAELSDALSRIPNTPLADVPVGADESANVVTRVVGAKPGWNHKPLEHFEIGEALGLMDFEGAARIA
GSRFTILKGQLARLERALGQFMLDLHTGEHGYIEVQPPLLVRDDAMYGTGQLPKFSDDLFRTTDGRWLIPTAEVPLTNMV
REQILDGEKLPLRFTALTPCFRSEAGSAGRDTRGMLRQHQFNKVELVSITDAESSIDEHERMTACAEEVLKRLGLHYRVM
TLCTGDMGFGARKTYDLEVWLPGQDAYREISSCSVCGDFQARRMNARYRGKEEKGTKFVHTLNGSGVALGRALIAVIENY
LNDDGSITVPDVLVPYMGGLRRIEKSA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-94 51