Gene Information

Name : SMa2213 (SMa2213)
Accession : NP_436440.1
Strain :
Genome accession: NC_003037
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 1239073 - 1240557 bp
Length : 1485 bp
Strand : -
Note : pfam00171, Aldehyde dehydrogenase; This family of dehydrogenases act on aldehyde substrates; Members use NADP as a cofactor; The family includes the following members: The prototypical members are the aldehyde dehydrogenases EC:1.2.1.3; Succinate-semialde

DNA sequence :
ATGCAAAACCTGCCGAAACTGTCCATGTATATCGACGGCCAATGGGTCGCCCCGGCATCAGGGGAATACATCGAGACGGT
GGATCCCTTCACCGCAAGGCCGTGGGCCCTTGTCCCACGCGGTAATGCGGAAGACGCAGATCGCGCGGTACGTGCGGCCC
ATCGTGCTTTCAGCCAGGGTCCTTGGGGCAAGATGCACCCGACCGAACGCGGACGCATTATCCAGAGGTTCGCCGCCCTG
ATCGAGGAGCACGCCGACGCGCTCGCCGACATCGAGGTGCGTGACAACGGTCGCCTGCTCGCCGAGATGACACATCAGAT
CCGCTACATCCCGCGCTGGTATCACTACTATGCCGGTTTTGCCGACAAGATCGAAGGTACGCTTCACCCCTGTGACAAGC
CTGCGCTGAGCTTTTCTCGTCACGAGCCGCTTGGCGTCTGCGTCGGCATCGTACCGTGGAACGCGCCGCTGCTCCTGTTC
TCCCTTAAGGCTGCCCCCGCCCTGGCGGCGGGTAACACATTGGTGATGAAGCCGGCCGAATTCACGTCCGCTACCGCGCT
CAAGTTGATGGAGCTGGTCGAGAAGGCCGGGTTCCCGACCGGCGTAATCAATGTCGTCACCGGCTACGGCCCTGAGGTCG
GCGAGCCGCTTGTCACGCATCCGCTGACCCGCCACGTGGGTTTCACCGGTTCGACGAAGACGGGCGCCCATCTCTATTCC
CTCGCTGCAAAAGACGTGAAGCGCGTAAGCCTCGAACTGGGCGGCAAATCCCCCAATATCGTCTTTGGCGATGCCGATCT
CGACAATGCGGTGCGCGGCGTTGTAGGGGGGATCTTCGGTGCCGTCGGCCAGACCTGTATTGCCGGCTCGCGTCTTTTGG
TGCACCGCTCAATCCACGACGAGTTCCTGGAGAAGCTGGCCGTCTTCACAAAGACGGCGCGTATCGGCGATCCGCGCAAG
GTCGAAACGCAGATCGGGCCGATCGCCAACAGCATGCAGTTCGAAAAGGTCCTCGGCTATATCGATATCGCTCGCCGGGA
AGGCGCCGAGCTCATCCTCGGCGGTGGGCGCCCCGACCTTGAGGAATGCGGCACCGGCTACTTTATCGAGCCCACCATTT
TCGCCGGCGTGAGCAACGACATGCGCATCGCGCGGGAGGAGGTGTTCGGCCCCGTTCTTTCGGCCATCGTGTTCGATGAA
CCCGAAGAAGCCCTCGCAATCGCCAATGACAGCGAGTTCGGTCTTGGTGCCGGCGTCTGGACCTCGGACATGCGCCTTGC
GCTGAAGATGTCGGAGCGCCTCGAGGCCGGTAGCGTCTGGGTCAATACCTATCGTGACATTTCCTACACAACGCCTTTTG
GCGGCTACAAGAAAAGCGGCATCGGACGCGAGAACGGCGTGGCCGGGATCTACGAATATCTGCAGACCAAAGCGGTCTGG
CTGTCGACCGCCGAAGAGATCGCAAATCCATTTGTAATCGGCTGA

Protein sequence :
MQNLPKLSMYIDGQWVAPASGEYIETVDPFTARPWALVPRGNAEDADRAVRAAHRAFSQGPWGKMHPTERGRIIQRFAAL
IEEHADALADIEVRDNGRLLAEMTHQIRYIPRWYHYYAGFADKIEGTLHPCDKPALSFSRHEPLGVCVGIVPWNAPLLLF
SLKAAPALAAGNTLVMKPAEFTSATALKLMELVEKAGFPTGVINVVTGYGPEVGEPLVTHPLTRHVGFTGSTKTGAHLYS
LAAKDVKRVSLELGGKSPNIVFGDADLDNAVRGVVGGIFGAVGQTCIAGSRLLVHRSIHDEFLEKLAVFTKTARIGDPRK
VETQIGPIANSMQFEKVLGYIDIARREGAELILGGGRPDLEECGTGYFIEPTIFAGVSNDMRIAREEVFGPVLSAIVFDE
PEEALAIANDSEFGLGAGVWTSDMRLALKMSERLEAGSVWVNTYRDISYTTPFGGYKKSGIGRENGVAGIYEYLQTKAVW
LSTAEEIANPFVIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 2e-74 44
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 7e-75 42
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 7e-75 42
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 7e-75 42
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-74 42
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 4e-71 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SMa2213 NP_436440.1 aldehyde dehydrogenase VFG0082 Protein 2e-71 41