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Name : leuS (CA_C0646) Accession : NP_347283.1 Strain : Clostridium acetobutylicum ATCC 824 Genome accession: NC_003030 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 751312 - 753750 bp Length : 2439 bp Strand : - Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGAGTACTTATAGTACAAAAGTTGATGAAAAATGGCAAAAAAAATGGGAAGAAACAAGTCTGTATAAATTTGATGAAAA TAATCTCGAAAAAAAATTATATGTTTTGGAGATGTTCTCTTATCCTTCTGGCGCAAAGCTTCATGCAGGACACTGGTTTA ACTATGCTCCAGTAGATTCCTGGGCAAGATTTAAAAAAATGACTGGTTATAATGTATTTCAACCAATGGGCTTTGATGCA TTTGGTCTTCCTGCTGAAAACTATGCTATAAAAACAGGAATTCACCCTAAGGACTCCACATTAAAAAATATTGAAACTAT GGAGAAACAGTTAAAATCTATGGGAGCAATGTTCAATTGGGATCATGAGGTAATAACTTGTACGCCTGATTATTATAAAT GGACTCAATGGTTGTTCTTAGAACTTTATAAAAACGGTCTTGCTTATAGAAAAAAAGCTCCTGCAAACTGGTGCCCTAGC TGTAATACGGTTTTAGCAAATGAACAAGTAGTAGATGGCTCTTGTGAGAGATGTGGAACAGAGGTTATAAAAAAAGATTT GACTCAGTGGTTCTTTAAAATAACTAATTATGCCGAAGAACTTCTCCAAAAATTAGATGAGCTTGATTGGCCTGAAAAAA CAAAGGCAATGCAAAAACATTGGATAGGTAAATCCAAAGGTGCTGAGGTAACCTTCAAGGTTGATAACAGTGACTTAAAA TTTGATGTATTTACAACAAGAGTAGACACTCTATGCGGTGTAACCTATGTAGTACTTGCACCTGAAAGCCCTCTAGCTGA TGAGCTTACAAAACCAGAATATAAAGAAAAAGTTGAAGAATATAAACTTCAAGCTCAAAAGCAATCTGAAATTGAAAGAC AATCACTTACAAGAGAAAAAACAGGAGTATTTACAGGCTCTTATGCAATCAATCCTATAAACAACAAGAAAGTACCTATA TGGATTGCGGATTACGTAATATACACTTACGGTACTGGTGCAGTTATGGCTGTCCCTTCACATGATGAAAGAGATTTTGC TTTTGCAACTAAATACGATCTTCCAATTGTGAGAGTTGTTGAAGGCGGTGAAGAGCTTCCTTTCACAGGTTATGGCCCAC TGGTTAACAGCGGTGAATTTGATGGTCTTAAAGGAAACAAAGCAAAGGAAGCTATTGTAAGTAAACTTTCTGAAAATGAT CTTGGAAGATGGAAGGTAAATTACAGACTTCGTGATTGGTTAGTTTCAAGACAAAGATATTGGGGTGCTCCAATACCAGT TGTTTACTGTGAAAAATGTGGAATAGTTCCTGTTCCTGAAAAAGATCTTCCAGTGGAATTGCCTTATAATGTAGAATTTA ATCCTACTGGTAAATCCCCTCTTACAACTTCTGAGGAATTTATGAACACAACTTGCCCTCATTGTGGAGGTCATGCTACA AGGGAATCCGATACTTTAGATACCTTTGTATGTTCATCCTGGTACTATTTGAGATATGCAGATAATGAAAATAGCGATGC ACCTTTTGATAAAGAAAAGATATCTAAAATGCTTCCTGTTGACAAATATGTTGGTGGACCTGAGCACGCATGTATGCATC TATTATATGCTAGATTTATCACAAAAGCATTAAGAGATATTGGATACCTTAATTTTGATGAACCATTTTTATCTTTAAGA CATCAAGGCTTAATTCTAGGTCCTGATGGTCAAAAAATGAGTAAATCTAAAGGAAATACTATTTCACCTGATGATATTAT AGCTGAGCACGGCTCTGATGTATTTAGAATGTATCTAATGTTTGGATTTGACTATGCTGAAGGCGGCGCATGGAGTGATG ACGGAGTTAAAGCCATGTCCAAATTTGTAGACAGATTTTCTAGAATGATTGAAACTGCAAAAGAAGAAATAAATAATCCT AAAAACTCAAAAACAGATATGGGAAAAGAAGAAAAAGAATTAAATTATGTTAGAAATCATTCAATTAAAGCTGTAACAGA AGATATGGATAAATTCCAGTTCAATACATGCATAGCTAGGCTTATGGAATTCACAAATTCTTTATCAAAATATCTAACTG TAGATAATAAAAATATTAAGCTTCTTAAAGACACCACTATTGATATTATAAAGCTGATAGCTCCATTTGCACCTCACTTT GCAGAAGAACAATGGAATATAATTGAGGAAAAATATTCAGTATTTAATGAAAAGTGGCCAGAATTTGATGAAAAAGCTCT TGTAAAAGATGAAGTTGAGATAGCTATTCAGATAAATGGCAAAATTAAAGCTAAAATAAATATTGCAACAAACTTAAGTG AAGATGAAATCAAATCTGCTGCACTAGCTGACGATAAAGTTAAAGCTGCTACTGACGGAAAGAATATAGTTAAGGTTATA GTTATAAAAGGACGTCTTGTAAACATAGTTGTTAAATAA Protein sequence : MSTYSTKVDEKWQKKWEETSLYKFDENNLEKKLYVLEMFSYPSGAKLHAGHWFNYAPVDSWARFKKMTGYNVFQPMGFDA FGLPAENYAIKTGIHPKDSTLKNIETMEKQLKSMGAMFNWDHEVITCTPDYYKWTQWLFLELYKNGLAYRKKAPANWCPS CNTVLANEQVVDGSCERCGTEVIKKDLTQWFFKITNYAEELLQKLDELDWPEKTKAMQKHWIGKSKGAEVTFKVDNSDLK FDVFTTRVDTLCGVTYVVLAPESPLADELTKPEYKEKVEEYKLQAQKQSEIERQSLTREKTGVFTGSYAINPINNKKVPI WIADYVIYTYGTGAVMAVPSHDERDFAFATKYDLPIVRVVEGGEELPFTGYGPLVNSGEFDGLKGNKAKEAIVSKLSEND LGRWKVNYRLRDWLVSRQRYWGAPIPVVYCEKCGIVPVPEKDLPVELPYNVEFNPTGKSPLTTSEEFMNTTCPHCGGHAT RESDTLDTFVCSSWYYLRYADNENSDAPFDKEKISKMLPVDKYVGGPEHACMHLLYARFITKALRDIGYLNFDEPFLSLR HQGLILGPDGQKMSKSKGNTISPDDIIAEHGSDVFRMYLMFGFDYAEGGAWSDDGVKAMSKFVDRFSRMIETAKEEINNP KNSKTDMGKEEKELNYVRNHSIKAVTEDMDKFQFNTCIARLMEFTNSLSKYLTVDNKNIKLLKDTTIDIIKLIAPFAPHF AEEQWNIIEEKYSVFNEKWPEFDEKALVKDEVEIAIQINGKIKAKINIATNLSEDEIKSAALADDKVKAATDGKNIVKVI VIKGRLVNIVVK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 4e-160 | 46 |
