Gene Information

Name : secA (CA_C2846)
Accession : NP_349450.1
Strain : Clostridium acetobutylicum ATCC 824
Genome accession: NC_003030
Putative virulence/resistance : Unknown
Product : preprotein translocase subunit SecA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG0653
EC number : -
Position : 2977874 - 2980393 bp
Length : 2520 bp
Strand : -
Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap

DNA sequence :
ATGGGACTGTTAGAGAAAATATTTGGTACATATAGTGATAGAGAAGTGAAAAGGATTATTCCTCTTGTTGATAAAATAGA
TGCACTAGATGGATCAATGCAAGCTTTAAGTGAGGATGAACTTAAAGCTAAAACTGCTGAATTTAAGCAGAGGTATGAAA
ATGGGGAAACACTTGATGATTTACTTGTTGAAGCATTTGCGGTGGTAAGAGAAGCTTCATCAAGAATTCTTGGCTTAAAG
CATTTTAGAGAGCAAATTATAGGTGGTATTGTACTTCATCAGGGAAGAATTTCAGAGATGAAAACCGGTGAAGGTAAAAC
ATTAGTTGCAACACTTCCGTCATATTTGAATGCAATTACAGGTAAGGGAGTTCATGTAGTAACAGTAAATGATTACCTTG
CAAAAAGAGATATGGAATGGATGGGACAGCTTTATCAATATCTTGGATTAACTACAGGGGTAATAGTTCATGATCTTGAT
CAAAAACAAAGACAGGAAGCTTATGCAGCAGATATAACCTACGGTACAAATAACGAGTTTGGATTTGATTATTTAAGAGA
TAACATGGTTATATATAAGGAAGAAAGAGTTCAAAGACCACTTCACTTTTGTATAGTTGACGAGGTGGACTCAATCTTAA
TAGATGAGGCAAGAACACCACTTATAATATCCGGAGAAGGAGAAAAATCCACTGAATTTTACAAGGTGGCTGACAACTTC
GCTAAGATGTTAAGGAAAGAAAAAGATTTTACTATTGATGAAAAAACTAATTCAGCAATACTAACAGATGAGGGTGTTGA
AAAGGCAGAAAAATATTATCATATTGACAACTATGCAGATCCACAAAACATGGAAATACAACATCATACATCTCAGGCAT
TAAAGGCAAATTATTTAATGAAACGTGATAAAGATTATATGGTAAAGGAAGATGAAGTAGTAATTGTAGACGAATTTACC
GGAAGACTTATGGAAGGTAGAAGATACAGTGATGGACTTCATCAAGCAATAGAAGCAAAAGAAGGTGTTAAGGTTCAAAA
AGAATCTAAGACACTTGCTACAATAACTTTCCAGAATTATTTTAGAATGTATGAAAAACTTTCTGGTATGACAGGTACTG
CATTAACAGAGGAAGTGGAGTTCAGAGAAATATATGGTCTTGACGTTGTTGTAATACCAACTCACAGACCTATAGCTAGA
ATAGATGCACCGGATATTGTATATAAGACTGAACTAGGAAAGTTTAAGGCAGTAGTTGAAGATATAGTAGAAACAAATAA
AAATGGGCAGCCTGTACTTGTTGGTACTGTAAGTATAGAAAAATCAGAACTTCTGTCATCATTGCTTAAAAAAAGAGGAG
TACGTCATCAGGTTTTAAATGCTAAGTATCATGAGCAAGAAGCAGAAATAATTTCACATGCAGGAGAAAAAGGCATGGTT
ACTATAGCAACTAATATGGCAGGACGTGGTACCGATATAAAGCTTGGAGAAGGAGTTACTGATGTAGGCGGTCTTAAGAT
AATAGGTACTGAAAGACATGAATCAAGACGTATAGATAATCAGCTTAGAGGTCGTGCTGGTCGTCAAGGAGATAAGGGAT
ATTCAAGATTTTATGTTTCACTGGAAGACGATCTTATGAGAATATTTGGTTCCGATAAGCTTAAAAACATGGTTGAAAAA
TTAGGTCTTGGAGACGACGATGCAATAGAAAGTAAGATGGTAAGTTCGGCTATAGAGAATGCTCAAAAGAAGGTTGAAGG
AAACAATTTTGACATAAGAAAAACTCTTATTCAGTACGATGATGTAATGAATAAACAGAGAGAAATCATCTACAAACAGA
GAAGTGAGGTTCTAGAAGGTGAAAACCTAAAGGATCAAATAGAAGGAATGATAAAAGACCTTATTTATAACGCTGTTAAT
TCACACATAAGTGGAGTAGATGAAGAGCTTGAATCAGATATCGAAGCAATTCTAAATTACCTTGATGATATATGTCTTCC
TAGAGGTATAGTTGAGGTTGAAGAACTTGCTACTATGTCAAATGATGAAATTAAAGAAAAGCTTTATTCTTTAGCTAAGG
AAATATATGAAAGAAAAGAAGAAGAGTTTTCTAGCGATCAAATGAGAGAACTTGAAAGAGTAATATTACTTAGAGTGGTT
GATACAAAGTGGATGGATCATATCGATAGTATGGAACACTTGAAACAAGGAATAGGACTTAGAGCATATAAGCAGCAGGA
TCCTACTCAAGCATATCAGATGGAAGGAAGCGATATGTTTGAAGAGATGGTAGAGAACATAAAAGTAGAAACCGTTAGGT
ATCTATTCCATGTTCAAGCTGAAAGAGCTCCTGAAAGACAGAGAGTTGTTAAAGAAACAGAGATAAATTACAGTGGACCA
GATGCTGGAGATACTAAGAAAGAGCCTGTAAGAAGAAAAGAAAAGAAGATAGGAAGAAACGATTTATGTCCTTGTGGCTC
TGGTAAAAAGTATAAGGATTGTTGTGGAAGAAGAGCATAA

Protein sequence :
MGLLEKIFGTYSDREVKRIIPLVDKIDALDGSMQALSEDELKAKTAEFKQRYENGETLDDLLVEAFAVVREASSRILGLK
HFREQIIGGIVLHQGRISEMKTGEGKTLVATLPSYLNAITGKGVHVVTVNDYLAKRDMEWMGQLYQYLGLTTGVIVHDLD
QKQRQEAYAADITYGTNNEFGFDYLRDNMVIYKEERVQRPLHFCIVDEVDSILIDEARTPLIISGEGEKSTEFYKVADNF
AKMLRKEKDFTIDEKTNSAILTDEGVEKAEKYYHIDNYADPQNMEIQHHTSQALKANYLMKRDKDYMVKEDEVVIVDEFT
GRLMEGRRYSDGLHQAIEAKEGVKVQKESKTLATITFQNYFRMYEKLSGMTGTALTEEVEFREIYGLDVVVIPTHRPIAR
IDAPDIVYKTELGKFKAVVEDIVETNKNGQPVLVGTVSIEKSELLSSLLKKRGVRHQVLNAKYHEQEAEIISHAGEKGMV
TIATNMAGRGTDIKLGEGVTDVGGLKIIGTERHESRRIDNQLRGRAGRQGDKGYSRFYVSLEDDLMRIFGSDKLKNMVEK
LGLGDDDAIESKMVSSAIENAQKKVEGNNFDIRKTLIQYDDVMNKQREIIYKQRSEVLEGENLKDQIEGMIKDLIYNAVN
SHISGVDEELESDIEAILNYLDDICLPRGIVEVEELATMSNDEIKEKLYSLAKEIYERKEEEFSSDQMRELERVILLRVV
DTKWMDHIDSMEHLKQGIGLRAYKQQDPTQAYQMEGSDMFEEMVENIKVETVRYLFHVQAERAPERQRVVKETEINYSGP
DAGDTKKEPVRRKEKKIGRNDLCPCGSGKKYKDCCGRRA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
secA2 YP_006310687.1 preprotein translocase subunit SecA2 Not tested FWisland_3 Protein 1e-135 42