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Name : guaA (CA_C2700) Accession : NP_349306.1 Strain : Clostridium acetobutylicum ATCC 824 Genome accession: NC_003030 Putative virulence/resistance : Unknown Product : GMP synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0519 EC number : 6.3.5.2 Position : 2821591 - 2823123 bp Length : 1533 bp Strand : - Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway DNA sequence : ATGGATAAACAGTTAGTTTTAGTTATTGATTTTGGTGGACAATATAACCAGCTTATAGCAAGAAGAGTAAGAGAACACAA TGTATATTGTGAAATAGTTCCATACACATATTCTATAGATAAAATAAAGGAAAAGAAGCCTAGTGCAGTAATATTTACTG GTGGACAAAACAGTGTGTATGGAGAAGATTCACCTAGGATGGATAAAGAAATTTTTGATCTTGGAGTTCCTGTTCTTGGA ATATGCTATGGTCATCAGCTTATAACTTATACTTTAGGTGGAGAAGTTATGGGTTCAGAAATAAGAGAATATGGAAAGAC TGATGTAACGCTAGATAGTGTTTGTGAATTATTTGAAGGAATAGATATAGAGAATTCTTGTTGGATGAGTCATACAGATA GAGTTGCAAAAGTTCCAGAGGGCTTTAAGGTGGTTGGTCATACTAATGTTTGTCCAGTGGCTGCAATGGCAAACACAGAG AAGAAGATATATGGAGTTCAGTTCCATCCAGAAGTTTTACATACTCCTTTTGGAGAGCAGCTTTTTTCAAATTTCTTATT TAAGATATGTGGTTTAAAAGAGGATTGGTCAATGTCTTCTTTTGCTAAAGAGAAAATTCAGGAGATTAAAGATATTGTAG GAGATAAAAAAGTTTTATGTGCTTTATCGGGTGGAGTAGATTCATCTGTTGCAGCAGTTTTAGTTCATAAAGCGATTGGT AAACAGCTTACTTGTGTATTTGTTGACCACGGTCTTCTTAGAAAAGATGAAGGTGACCAGGTTGAAAGTATTTTTAGAAA ACAATTTGATATGAATCTTATAAGAGTTAATGCTAAGGATAGATTTCTTGGAAAACTAAAAGGAATTTCTGATCCAGAAA GAAAGAGAAAAATAATAGGAGAAGAGTTCATAAGAGTTTTTGAAGAAGAAGCAAATAAACTTGGACAAATAGATTTCCTA GTTCAAGGAACAATTTATCCAGATGTTGTTGAAAGTGGAACAGATACTTCTGCAACTATAAAGAGCCATCATAATGTTGG TGGACTTCCAGAGGATATGCAGTTTGAACTTATAGAGCCATTAAGAGAGCTTTTTAAAGATGAAGTAAGAGCGGTAGGAG AGGAACTAGGAATTCCTCATAAGCTTGTATGGCGTCAACCATTCCCAGGACCAGGTCTTGGAATAAGAGTTCTTGGAGAA GTAACTGAAGAAAAGCTTGAAATTGTAAGAGAAGCAGATGCTATTTTTAGAGAAGAAATTGCAAATGCAGGACTTGAAGA AAAGATATGGCAGTACTTTGCATGTCTTCCAAACATTCATTCTGTTGGAGTTATGGGTGATGGAAGAACTTACTGCGAAA CTATAGCTTTAAGAGCTGTAACTTCTTCAGATGCTATGACTTCTGATTGGGCGAGAATACCATATGAGGTTTTAGATAAA GTTTCAAGAAGAATAGTAAATGAGGTTAAAGGTGTTAACAGAATAGTTTATGATGTAACTAGTAAGCCACCAGCTACAAT TGAGTGGGAATAA Protein sequence : MDKQLVLVIDFGGQYNQLIARRVREHNVYCEIVPYTYSIDKIKEKKPSAVIFTGGQNSVYGEDSPRMDKEIFDLGVPVLG ICYGHQLITYTLGGEVMGSEIREYGKTDVTLDSVCELFEGIDIENSCWMSHTDRVAKVPEGFKVVGHTNVCPVAAMANTE KKIYGVQFHPEVLHTPFGEQLFSNFLFKICGLKEDWSMSSFAKEKIQEIKDIVGDKKVLCALSGGVDSSVAAVLVHKAIG KQLTCVFVDHGLLRKDEGDQVESIFRKQFDMNLIRVNAKDRFLGKLKGISDPERKRKIIGEEFIRVFEEEANKLGQIDFL VQGTIYPDVVESGTDTSATIKSHHNVGGLPEDMQFELIEPLRELFKDEVRAVGEELGIPHKLVWRQPFPGPGLGIRVLGE VTEEKLEIVREADAIFREEIANAGLEEKIWQYFACLPNIHSVGVMGDGRTYCETIALRAVTSSDAMTSDWARIPYEVLDK VSRRIVNEVKGVNRIVYDVTSKPPATIEWE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| guaA | YP_001331415.1 | GMP synthase | Not tested | vSa¥á | Protein | 2e-160 | 63 |
| SAMSHR1132_03620 | YP_005324884.1 | GMP synthase | Not tested | vSa¥á | Protein | 1e-160 | 63 |
| SAPIG0468 | YP_005733278.1 | GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) | Not tested | SAPI-S0385 | Protein | 9e-161 | 63 |
| guaA | NP_938969.1 | GMP synthase | Not tested | Not named | Protein | 5e-145 | 55 |
