Gene Information

Name : serS (CA_C0021)
Accession : NP_346668.1
Strain : Clostridium acetobutylicum ATCC 824
Genome accession: NC_003030
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 30670 - 31944 bp
Length : 1275 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGATTTAAAAAGAATAAGAACTAATCCAGAAGAAATAAAAAAGGCACTAACAAACAGAGGAGAAGATTTCGATAT
TTCTGTCATAGATGAGCTTGTATCTCTTGACGAAGAAAGAAGAAAAAATCTTGTAGAGGTAGAAAATTTAAAAAGTAAAA
GAAATAAAGATTCTGGCGAGATAGCTAAGCTTAAAAAGTCAGGACAAAATGCGGATGAATTACTTGCTGAAATGAAGAAG
ATTTCAGATGATATAAAAGGAATAGATGCTAAGGTATCAGAAATAGATGAAAAAATGCAGTACATAATGCTTAGAATACC
TAATATACCACATCCTAGCGTTCCAGAAGGTAAGTCAGATGAGGAAAATGTAGAAATAAGAAAATGGGGAGAGCCTAGAA
AATTCGACTTTGAGTTTAAAGCACACTGGGATATAGGAACAGATTTAGGGCTTCTTGATTTTGAAAGAGGAGGAAAAGTC
GCAGGTTCTAGATTTACATTCTATAAGGGACTTGGTGCAAGACTTGAAAGAGCAGTTATAAACTATTTCCTTGATACTCA
TGTAGAAAAACACGGATATACTGAAATCCTCCCACCATACATGGTTAATAGAGTTAGTATGACTGGTACTGGACAGTTGC
CTAAATTTGAAGAGGATGCTTTTAAAGTAGATAATGGATTCTTTTTAATTCCTACAGCTGAAGTTCCTGTTACTAATATG
TTCAGAGACGAAATATTAAAAGCAGAAGATTTACCATATAAGTTTGCTGCATACAGTGCATGCTTTAGATCAGAAGCAGG
CTCAGCAGGAAGAGATACAAGAGGACTTGTTCGTCAGCATCAATTTAATAAGGTAGAGCTTGTTAAGTTTGCCAAACCAG
AAGAATCTTATGATGAACTTGAAAAATTAACTCATGATGCAGAGGAAATTTTACAAATATTAAATATTCCTTATAGAGTG
GTTAGAATATGTAAGGGAGATTTAGGCTTTACAGCAGCTTTAAAGTACGATATAGAAGTATGGATGCCTAGCTACGGAAG
ATATGTTGAAATTTCAAGCTGTAGTAACTTCGAGGATTTCCAAGCAAGACGTGCAAACATTAAATTTAGAAGAGATCCAA
AGGCTAAACCTGAATTTGTTCACACTCTTAATGGATCAGGTCTTGCTGTTGGAAGAACAGTTGCAGCAATACTAGAAAAT
TATCAAAATGAAGATGGAAGTGTAAATGTTCCAGAAGCGTTAAAGAAATATATAGGAAAAGACGTTATAAGATAA

Protein sequence :
MLDLKRIRTNPEEIKKALTNRGEDFDISVIDELVSLDEERRKNLVEVENLKSKRNKDSGEIAKLKKSGQNADELLAEMKK
ISDDIKGIDAKVSEIDEKMQYIMLRIPNIPHPSVPEGKSDEENVEIRKWGEPRKFDFEFKAHWDIGTDLGLLDFERGGKV
AGSRFTFYKGLGARLERAVINYFLDTHVEKHGYTEILPPYMVNRVSMTGTGQLPKFEEDAFKVDNGFFLIPTAEVPVTNM
FRDEILKAEDLPYKFAAYSACFRSEAGSAGRDTRGLVRQHQFNKVELVKFAKPEESYDELEKLTHDAEEILQILNIPYRV
VRICKGDLGFTAALKYDIEVWMPSYGRYVEISSCSNFEDFQARRANIKFRRDPKAKPEFVHTLNGSGLAVGRTVAAILEN
YQNEDGSVNVPEALKKYIGKDVIR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 4e-122 61